Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 271, P. 116987 - 116987
Published: Nov. 29, 2024
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 709 - 709
Published: Jan. 15, 2025
Nanozymes, a kind of nanoparticles with enzyme-mimicking activities, have attracted considerable attention due to their robust catalytic properties, ease preparation, and resistance harsh conditions. By combining nanozymes surface-enhanced Raman spectroscopy (SERS) technology, highly sensitive selective sensors been developed. These are capable detecting wide range analytes, such as foodborne toxins, environmental pollutants, biomedical markers. This review provides an overview recent advancements in the synthesis surface modification nanozymes, highlighting ability mimic multiple enzymes enhance performance. In addition, we explore development applications nanozyme-based SERS food contaminants, The concludes perspectives challenges facing field, involving need for deeper understanding nanozyme principles mechanisms, standardized systems characterization, engineering tailored properties specific applications. Finally, discuss potential integrating various techniques create multi-modal detection platforms, paving way next generation analytical tools fields safety, monitoring, diagnostics.
Language: Английский
Citations
2
Pathogens, Journal Year: 2025, Volume and Issue: 14(2), P. 111 - 111
Published: Jan. 23, 2025
Dental caries is the most common oral disease in world and a chronic infectious disease. The cariogenic microbiome plays an important role process of caries. ecological imbalance microbiota leads to low pH, which causes Therefore, antibacterial materials have always been hot topic. Traditional such as cationic agents, metal ion some natural extract agents good effects. However, they can cause bacterial resistance poor biological safety when used for long-term purposes. Intelligent materials, pH-responsive nanozymes, photoresponsive piezoelectric living are emerging nano-strategies that respond microenvironment or other specific stimuli exert Compared with traditional these less prone resistanceand safety. This review summarizes characteristics materials. These accurately act on microenvironment, showing intelligent effects providing new ideas management.
Language: Английский
Citations
1
Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 26, 2025
Developing sensitive and highly active nanozymes for antioxidant analysis is of the utmost significance in medical diagnosis health monitoring due to their essential roles as free reactive oxygen species scavengers. Here, six metal-organic frameworks (MOFs)-based are developed a dual-mode absorbance/image colorimetric sensor array simultaneous discrimination determination various antioxidants with comparable structural or chemical properties. The catalysts exhibit wide range potent oxidase-like catalytic activities, verified by kinetic parameters, presence dispersed transition metallic bimetallic redox nodes. These efficiently catalyze oxidation colorless 3,3',5,5'-tetramethylbenzidine (TMB) blue TMBox, resulting noticeable absorption RGB color changes at 650 nm. Various demonstrate different reducing capabilities leading generation fingerprint-like spectral patterns. pattern recognition chemometrics methods including principal component (PCA) linear discriminant (LDA) represent well-separated clustering ascorbic acid, dopamine, uric cysteine, glutathione, thiocyanate, tannic gallic acid. assay provides detection (0.1-75 μM) limits low 30 nM. successfully discriminated concentrations, mixtures, interferences. Furthermore, sensor's applicability biologically relevant was validated urine plasma samples. Overall, MOF-based nanozyme offers promising platform discriminating determining potential applications.
Language: Английский
Citations
1
Advanced Sensor and Energy Materials, Journal Year: 2025, Volume and Issue: unknown, P. 100141 - 100141
Published: March 1, 2025
Language: Английский
Citations
0
Phenomics, Journal Year: 2025, Volume and Issue: unknown
Published: March 4, 2025
Language: Английский
Citations
0
Biosensors, Journal Year: 2024, Volume and Issue: 14(4), P. 170 - 170
Published: March 31, 2024
The discrimination and recognition of biological targets, such as proteins, cells, bacteria, are utmost importance in various fields research production. These include areas like medicine, clinical diagnosis, microbiology analysis. In order to efficiently cost-effectively identify a specific target from wide range possibilities, researchers have developed technique called differential sensing. Unlike traditional “lock-and-key” sensors that rely on interactions between receptors analytes, sensing makes use cross-reactive receptors. offer less specificity but can cross-react with analytes produce large amount data. Many pattern strategies been shown promising results identifying complex analytes. To create advanced sensor arrays for higher analysis efficiency larger recognizing range, nanomaterials utilized probes. possess distinct molecular affinities, optical/electrical properties, compatibility, conveniently functionalized. this review, our focus is recently reported optical utilize discriminate bioanalytes, including bacteria.
Language: Английский
Citations
3
Biosensors, Journal Year: 2024, Volume and Issue: 14(7), P. 342 - 342
Published: July 15, 2024
Misusage of tetracycline (TC) antibiotics residue in animal food has posed a significant threat to human health. Therefore, there is an urgent need develop highly sensitive and robust assays for detecting TC. In the current study, gold platinum nanoparticles were deposited on carbon nanotubes (CNTs) through superposition method (Au@Pt/CNTs-s) one-pot (Au@Pt/CNTs-o). Au@Pt/CNTs-s displayed higher enzyme-like activity than Au@Pt/CNTs-o, which utilized development magnetic immunoassays. Under optimized conditions, limits detection (LODs) immunoassays assisted by Au@Pt/CNTs-o against TCs could reach 0.74 ng/mL 1.74 ng/m, respectively, improved 6-fold 2.5-fold comparison with conventional immunoassay. addition, measurement TC-family was implemented this assay, ascribed antibody used that recognize TC, oxytetracycline, chlortetracycline, doxycycline high cross-reactivity. Furthermore, showed good accuracy (recoveries, 92.1-114.5% milk; 88.6-92.4% pork samples), also applied determination targets real samples. This study provides novel insights into rapid based high-performance nanocatalysts.
Language: Английский
Citations
3
Nanoscale, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 6, 2024
This review provides a comprehensive insight into the latest research advancements in developing novel nanoparticle-based synergistic strategies mainly for remineralization of dental hard tissues and inhibition cariogenic biofilms.
Language: Английский
Citations
3
Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: March 27, 2025
Pathogenic Escherichia coli (E. coli) is a widespread and clinically significant foodborne pathogen. Due to its high mutation rates phenotypic diversity, rapid identification of subtypes remains challenging prone false positives when detecting single strains. In this study, we developed plasmonic sensor array with high-dimensional signal readouts (ζ-potential, dynamic light-scattering (DLS), surface-enhanced Raman scattering (SERS), ultraviolet-visible (UV-vis) absorption spectra) for the selective discrimination pathogenic E. coli, integrated bacterial culture methods. The units demonstrated strong encoding capabilities, facilitating differentiation subtle variations among various strains showing excellent anti-interference performance. realized different strains, mixture identification, even quantitative detection. Remarkably, working concentration was notably low, at 104 CFU/mL. Finally, by incorporating isolation culture, designed obtained 100% accuracy in real food samples. These findings highlight array's potential applications safety monitoring clinical diagnostics, offering sensitive, rapid, reliable tool pathogen detection complex
Language: Английский
Citations
0
Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12
Published: Oct. 17, 2024
Nanozymes, synthetic nanomaterials that mimic the catalytic functions of natural enzymes, have emerged as transformative technologies for biosensing, diagnostics, and environmental monitoring. Since their introduction, nanozymes rapidly evolved with significant advancements in design applications, particularly through integration machine learning (ML). Machine (ML) has optimized nanozyme efficiency by predicting ideal size, shape, surface chemistry, reducing experimental time resources. This review explores rapid technology, highlighting role ML improving performance across various bioapplications, including real-time monitoring development chemiluminescent, electrochemical colorimetric sensors. We discuss evolution different types nanozymes, mechanisms, impact on property optimization. Furthermore, this addresses challenges related to data quality, scalability, standardization, while future directions ML-driven development. By examining recent innovations, highlights potential combining drive next-generation diagnostic detection technologies.
Language: Английский
Citations
2