Immunomodulatory hydrogel neutralizes tumor acidity to augment immune responses for the prevention of post-surgical recurrence of melanoma DOI

Zhiyuan Quan,

Linghui Chen, Beibei Chen

et al.

Science China Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 19, 2024

Language: Английский

Copper-Based Biomaterials for Anti-Tumor Therapy: Recent Advances and Perspectives DOI
Shufang Zhang, Shuping Peng

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

5

An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications DOI Creative Commons

Nazrah Maher,

Anum Mahmood,

Muhammad Amber Fareed

et al.

Journal of Advanced Research, Journal Year: 2024, Volume and Issue: unknown

Published: July 1, 2024

Surface coating of dental implants with a bioactive biomaterial is one the distinguished approaches to improve osseointegration potential, antibacterial properties, durability, and clinical success rate implants. Carbon-based coatings, unique class that possesses excellent mechanical high chemical thermal stability, osteoconductivity, corrosion resistance, biocompatibility, have been utilized successfully for this purpose. This review aims present comprehensive overview structure, techniques, application various carbon-based coatings implant applications particular focus on nanomaterial (CNMs), which an advanced biomaterials. Available articles carbon were reviewed using PubMed, Science Direct, Google Scholar resources. are non-cytotoxic, highly biocompatible, chemically inert, osteoconductive, allows bone cells come into close contact surface prevents bacterial attachment growth. Current research advancements now more focused as emerging advantage both nanotechnology aligns closely ideal material characteristics. Carbon nanotubes, graphene, its derivatives received most attention coating. Various techniques available materials, chosen according substrate type, requirements, desired thickness. Vapor deposition technique, plasma spraying, laser deposition, spraying commonly employed coat structures surface. Longer duration trials monitoring required ascertain role applications.

Language: Английский

Citations

9

Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications DOI Creative Commons
Jun Song,

Minghao Kang,

Shujian Ji

et al.

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(2), P. 81 - 81

Published: Jan. 7, 2025

Fluorescent carbon dots, especially red/near-infrared-emitting CDs, are becoming increasingly important in the field of biomedicine. This article reviews synthesis, fluorescence mechanisms, and biological applications R/NIR-CDs, emphasizing importance source solvent selection controlling their optical properties. The formation process CDs is classified, mechanisms summarized, involving core states, surface molecular cross-linking enhanced emission effects. also highlights R/NIR-CDs bioimaging, biosensing, phototherapy, drug delivery. final section discusses challenges prospects.

Language: Английский

Citations

1

Optimization of Cancer Immunotherapy Through Synergistic Enhancement of Immunogenic Cell Death by Multifunctional Nanobioreactors Combined with Immune Checkpoint Inhibitors DOI
Hui Zhang, Chunyu Qu, Ziqing Yang

et al.

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 28, 2025

Language: Английский

Citations

0

Glucose oxidase/copper‑carbon dots/hyaluronic acid self-assembly for self-supply hydrogen peroxide in a double-enzyme cascade to enhance anti-tumor therapy DOI
Yuting Lu, Xu Zhu,

Yibo Huo

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 310, P. 143286 - 143286

Published: April 17, 2025

Language: Английский

Citations

0

Unveiling the protective role of recombinant snow flea antifreeze protein expressed by Komagataella phaffii in cryopreservation of EA.hy926 cells DOI

Yishan Fu,

Bo Zeng,

Yangyang Li

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143295 - 143295

Published: April 1, 2025

Language: Английский

Citations

0

Liquid metal-based nanocomposite with triple-amplified Fenton-like reaction for tumor chemodynamic/photothermal/immunotherapy DOI
Shuai Wang, Yang Zou, Li Zhang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163326 - 163326

Published: May 1, 2025

Language: Английский

Citations

0

Engineering Cu‐Fe3O4/Polymer Dots Hybrids for Dual‐Mode Detection of Chlortetracycline, Recognition‐Enhanced Water Pollutant Degradation, and Bacterial Disinfection DOI
Tao Zhang, Xia Qü, Siwei Sun

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: May 13, 2025

Abstract Antibiotic residues in medical sewage pose public health risks, necessitating integrated detection‐degradation solutions. Here, a novel Cu‐Fe 3 O 4 /Polymer Dots hybrid (CP), featuring specific recognition of chlortetracycline (CTC), restoration peroxidase (POD)‐like activity, and outstanding fluorescence characteristics, is successfully constructed using nanoparticles (CFO) as the core, with polymer dots (PDs) functionalizing outer layer. Leveraging unique properties CP, multifunctional platform developed for simultaneous fluorescence/colorimetric detection CTC, well photothermal recognition‐enhanced POD activity antibiotic degradation bacterial disinfection. The limit (LOD) CTC by CP are determined to be 1.86 n M 64.2 nM colorimetric detection, respectively. Comprehensive characterization reveals that quenching occurred via dynamic mechanisms, primarily through intermolecular collisions. collision between leads release PDs, thereby exposing active catalytic sites reactivating POD‐like which not only achieves accurate but also facilitates disinfection water bacteria. This work introduces approach design recognition‐functionalized nanozymes offers promising strategy environmental monitoring remediation pollutants.

Language: Английский

Citations

0

Hesperidin Derivatives Contained Hydrogel Dressing for Photothermal Treatment of Melanoma and Postoperative Tissue Regeneration DOI

Jiaqian He,

Zheng Zhou, Wenxiang Zhu

et al.

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Melanoma is a severe malignant skin tumor. It crucial to effectively eliminate melanoma and promote rapid healthy regeneration of postoperative tissue defects. Herein, hesperidin derivatives (HD) have been developed as the bioactive components hydrogels that are capable ablating via photothermal therapy (PTT) promoting regeneration. HD prepared by heating alkaline solution followed dialysis lyophilization, GelMA encapsulating kill cancer cells bacteria under near-infrared (NIR) irradiation. The in vitro test vivo transcriptomic analysis confirmed containing induce immunogenic cell death (ICD) effect tumor significantly upregulating chemokine-related, cytokine-related, apoptosis-related genes, thereby enhancing therapeutic efficacy. In mouse model infected wounds, 808 nm light irradiation promoted wound repair. This was achieved through accelerated closure enhanced regeneration, mediated increased angiogenesis collagen deposition. conclusion, provide new strategy for clinical treatment defect repair following operative resection cancer.

Language: Английский

Citations

0

Multi-functional copper-manganese Nanozyme-Driven integrated platform for Fluorescence/Colorimetric Dual-Mode Detection, catalytic degradation of oxytetracycline and antibacterial disinfection DOI
Tao Zhang,

Zerun Zhang,

Siwei Sun

et al.

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 133751 - 133751

Published: May 1, 2025

Language: Английский

Citations

0