Development of a Microfluidic System for Mitochondrial Extraction, Purification, and Analysis DOI

Rukhsar Ajmal,

Weisen Zhang,

Hui Liu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 4, 2025

Mitochondria, as essential cellular organelles, play a key role in numerous diseases, from neurodegenerative disorders to cancer and rare conditions. The extraction of mitochondria cells has many applications disease diagnosis, pathological research, emerging mitochondrial transplantation therapy (MTT). Recent advancements microfluidic-on-chip systems offer promising improvements by enabling high-throughput processing, precise control, flexibility while facilitating integration with other devices platforms. Despite growing interest microfluidic (MME), there is lack comprehensive reviews on the latest developments this field. This review aims summarize recent well advantages limitations MME, providing deeper insights into microfluidic-based approaches for extraction, purification, analysis.

Language: Английский

Recent advancements in the applications of separation and enrichment strategies towards SERS detection DOI

Dongjie Zhang,

Huandi Li,

Xiao Li

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: 184, P. 118136 - 118136

Published: Jan. 7, 2025

Language: Английский

Citations

3
SERS-based microfluidic sensor for sensitive detection of circulating tumor markers: A critical review DOI
Yeru Wang, Rongke Gao,

Changbiao Zhan

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 523, P. 216289 - 216289

Published: Oct. 23, 2024

Language: Английский

Citations

5
CTCs Detection Methods In Vivo and In Vitro and Their Application in Tumor Immunotherapy DOI Open Access
Xiujie Sui, Jiahao Ji, Hongyi Zhang

et al.

Journal of Surgical Oncology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

ABSTRACT Circulating tumor cells (CTCs) are that detach from the primary site and enter bloodstream. They hold significant value for early detection, diagnosis, treatment of tumors. CTC detection methods can be classified into in vivo vitro techniques. Compared to traditional methods, causes less harm body allows earlier identification malignant tumors, thereby enabling timely improving patient survival rates. In recent years, has been widely used assess effectiveness immunotherapy. Dynamic monitoring CTCs help optimize clinical strategies. This review summarizes latest discusses their applications immunotherapy various common aiming provide better guidance support practice.

Language: Английский

Citations

0
Bio-Inspired AS1411-Functionalized Membrane for Specific and Non-Destructive Capture of Tumor Cells DOI
Yangyang Li,

Riyue Shu,

Cheng Zeng

et al.

Journal of Membrane Science, Journal Year: 2025, Volume and Issue: unknown, P. 123833 - 123833

Published: Feb. 1, 2025

Language: Английский

Citations

0
Development of a Microfluidic System for Mitochondrial Extraction, Purification, and Analysis DOI

Rukhsar Ajmal,

Weisen Zhang,

Hui Liu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 4, 2025

Mitochondria, as essential cellular organelles, play a key role in numerous diseases, from neurodegenerative disorders to cancer and rare conditions. The extraction of mitochondria cells has many applications disease diagnosis, pathological research, emerging mitochondrial transplantation therapy (MTT). Recent advancements microfluidic-on-chip systems offer promising improvements by enabling high-throughput processing, precise control, flexibility while facilitating integration with other devices platforms. Despite growing interest microfluidic (MME), there is lack comprehensive reviews on the latest developments this field. This review aims summarize recent well advantages limitations MME, providing deeper insights into microfluidic-based approaches for extraction, purification, analysis.

Language: Английский

Citations

0