Partitioned Microneedle Patch Based on NO Release and HSP Inhibition for mPTT/GT Combination Treatment of Melanoma
Dihua Yu,
No information about this author
Jiaojiao Tao,
No information about this author
Bingjie Wang
No information about this author
et al.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(37), P. 49104 - 49113
Published: Sept. 5, 2024
Photothermal
therapy
(PTT)
shows
promise
in
cancer
treatments
due
to
its
good
spatiotemporal
selectivity
and
minimal
invasiveness.
However,
PTT
has
some
problems
such
as
excessive
heat
damage
normal
tissues,
tumor
thermo-resistance
caused
by
shock
proteins
(HSPs),
limited
efficacy
of
monotherapy.
Here,
we
construct
a
patch
named
"partitioned
microneedles"
(PMN-SNAP/CuS),
which
separates
the
"catalyst"
bovine
serum
albumin-based
copper
sulfide
nanoparticles
(CuS@BSA
NPs)
"reactant"
Language: Английский
Anti‐Tumor Strategies Targeting Nutritional Deprivation: Challenges and Opportunities
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 2, 2025
Higher
and
richer
nutrient
requirements
are
typical
features
that
distinguish
tumor
cells
from
AU:
cells,
ensuring
adequate
substrates
energy
sources
for
cell
proliferation
migration.
Therefore,
deprivation
strategies
based
on
targeted
technologies
can
induce
impaired
viability
in
which
more
sensitive
than
normal
cells.
In
this
review,
nutrients
required
by
related
metabolic
pathways
introduced,
anti-tumor
developed
to
target
described.
addition
the
nutritional
characteristics
of
other
microenvironment
(including
macrophages,
neutrophils,
natural
killer
T
cancer-associated
fibroblasts)
new
also
summarized.
conclusion,
recent
advances
targeting
blockade
reviewed,
challenges
prospects
these
discussed,
theoretical
significance
optimizing
clinical
application
nutrition
strategies.
Language: Английский
Copper-based metal–organic frameworks for antitumor application
Yangwei Qian,
No information about this author
Chenxi Wang,
No information about this author
Risheng Xu
No information about this author
et al.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: Feb. 22, 2025
It
is
urgent
to
exploit
multifunctional
materials
and
combined
approaches
for
efficient
antitumor
effects.
Copper-based
metal–organic
frameworks
(Cu-MOFs)
have
excellent
performances
in
catalysis,
biocompatibility,
photothermal
conversion,
regulate
metabolism,
which
make
them
attract
more
attention
application.
Therefore,
this
review,
representative
ligands,
synthetic
methods,
mechanism,
applications
of
Cu-MOFs
were
provided.
Special
emphasis
placed
on
the
recent
drug
carriers,
therapy,
tumor
imaging,
theranostic,
are
summarized
with
examples.
Finally,
we
presented
dilemma
faced
by
offered
a
new
perspective
future
Hopefully,
review
may
serve
as
reference
further
development
application
Cu-MOFs.
Language: Английский
Harnessing stimuli-responsive NO nanomaterials for advanced multi-disease therapy
Coordination Chemistry Reviews,
Journal Year:
2025,
Volume and Issue:
533, P. 216540 - 216540
Published: Feb. 27, 2025
Language: Английский
Diversified nanocarrier design to optimize glucose oxidase-mediated anti-tumor therapy: Strategy and progress
Yuhan Fu,
No information about this author
Jialin Sun,
No information about this author
Chunyu Yang
No information about this author
et al.
International Journal of Biological Macromolecules,
Journal Year:
2025,
Volume and Issue:
unknown, P. 141581 - 141581
Published: Feb. 1, 2025
Language: Английский
Pillar[5]arene-based supramolecular nano-photosensitizer enhances cancer therapeutic effectiveness by generating multiple hypertoxic reactive species
Colloids and Surfaces A Physicochemical and Engineering Aspects,
Journal Year:
2024,
Volume and Issue:
700, P. 134781 - 134781
Published: Nov. 1, 2024
Language: Английский