Multifunctional Ti3C2@PDA/CuO2 Nanoplatform for Synergistic Photothermal, Photodynamic and Photothermal-Enhanced Chemodynamic Antibacterial Therapy DOI

Lianyuan Ge,

Simin Yuan, Xiaohong Wang

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 21, 2024

Language: Английский

Injectable dual-network hydrogel for phototherapy and immunomodulation in the treatment of MRSA-infected and diabetic wound DOI

Shengfei Bao,

Aodi Jiang,

Peng Li

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163026 - 163026

Published: April 1, 2025

Language: Английский

Citations

0
Aptamer-Driven Multifunctional Nanoplatform for Near-Infrared Fluorescence Imaging and Rapid In Situ Inactivation of Salmonella typhimurium DOI

Ning Ding,

Bo Zhang, Eslam M. Hamed

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Salmonella typhimurium (S. typhimurium) is a prominent pathogen responsible for intestinal infections, primarily transmitted through contaminated food and water. This underscores the critical need precise biocompatible technologies enabling early detection intervention of bacterial colonization in vivo. Herein, multifunctional nanoplatform (IR808-Au@ZIF-90-Apt) was designed, utilizing an S. typhimurium-specific aptamer to initiate cascade responses triggered by intracellular ATP GSH. The precisely targets typhimuriumvia recognition, promoting aggregation nanoparticle sedimentation oscillatory system. Furthermore, intelligent significantly enhances sensitivity based on near-infrared (NIR) fluorescence signals, achieving limit as low 2 CFU mL–1. Additionally, situ NIR irradiation applied at 30 min peak detection, rapid irreversible inactivation synergistic effects photothermal photodynamic effects. Importantly, mouse model infection, successfully detected achieved highly efficient without adversely affecting major organs. In conclusion, localized typhimurium, offering valuable insights disease surveillance epidemiological studies, with promising implications safety public health.

Language: Английский

Citations

0
A Targeted Core–Shell ZIF-8/Au@Fe3O4 Platform with Multiple Antibacterial Pathways for Infected Skin Wound Regeneration DOI
Jing Zhang, Xue Yang, Lan Zhang

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Bacterial infections seriously retard skin wound healing. To enhance the antibacterial efficiency and subsequent regeneration, a core-shell structured therapeutic platform, named FZAM, was designed with multiple antimicrobial pathways. FZAM consists of nanosized Fe3O4 as core ZIF-8 loaded Au nanoparticles (NPs) maltodextrin shell. NPs form heterojunction that generates hyperthermia abundant reactive oxide species (ROS) under near-infrared (NIR) irradiation. This also exhibits outstanding peroxidase-like activity. When bacteria invade, plays targeting effect to increase interaction between bacteria, synergistic action NIR-induced ROS well Zn2+ from ZIF-8, kills more than 99% at 200 μg mL-1. Fortunately, is cytocompatible even promotes biofunctions fibroblasts endothelial cells. In infected models, sterilizes NIR irradiation subsequently reduces inflammatory response accelerates regeneration. work provides therapy platform for treating infection assistance helping

Language: Английский

Citations

0
MXenes in microbiology and virology: from pathogen detection to antimicrobial applications DOI
Begüm Sarac, Seydanur Yücer, Fatih Çiftçi

et al.

Nanoscale, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

MXenes, a rapidly emerging class of two-dimensional materials, have demonstrated exceptional versatility and functionality across various domains, including microbiology virology.

Language: Английский

Citations

0
An acidity-triggered aggregation nanoplatform based on degradable mesoporous organosilica nanoparticles for precise drug delivery and phototherapy of focal bacterial infection DOI
Yunhan Huang, Wei Guo, Xinyu Wang

et al.

Dalton Transactions, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

An acidity-triggered aggregation antibacterial nanoplatform based on biodegradable mesoporous organic silica nanoparticles, is reported. It enables precise drug release and spatial accuracy for photodynamic therapy photothermal therapy.

Language: Английский

Citations

1
HAase/GSH dual-responsive mesoporous organosilica nanoparticles for synergistic photodynamic/photothermal/pharmacological antibacterial therapy DOI
Wei Guo, Yunhan Huang, Jane Pei‐Chen Chang

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(46), P. 19462 - 19471

Published: Jan. 1, 2024

A dual-responsive, biodegradable nanoplatform based on mesoporous organosilica nanoparticles, is reported. It enables multimodal synergistic antibacterial therapy of photodynamic/photothermal/pharmacological therapy.

Language: Английский

Citations

0
Multifunctional Ti3C2@PDA/CuO2 Nanoplatform for Synergistic Photothermal, Photodynamic and Photothermal-Enhanced Chemodynamic Antibacterial Therapy DOI

Lianyuan Ge,

Simin Yuan, Xiaohong Wang

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 21, 2024

Language: Английский

Citations

0