Prussian Blue Based Nanomaterials for Bacterial Detection and Killing Application

ACS Materials Letters, Journal Year: 2025, Volume and Issue: unknown, P. 595 - 609

Published: Jan. 16, 2025

The Prussian blue (PB) based nanomaterials have excellent photophysical and chemical properties, including strong photothermal conversion ability, multiple catalytic activities, porous structure, high specific surface area, good stability. Furthermore, as an FDA-approved antidote for heavy metal radioactive element poisoning, PB-based do not provoke significant immune responses or other adverse effects, demonstrating biocompatibility. its analogues (PB/PBAs) possess unique optical allowing the construction of highly sensitive biosensors disease diagnosis phototherapy. With advances in nanotechnology, a variety nanoplatforms on PB/PBAs been developed detection bacterial killing. This review mainly introduces synthesis methods summarizes research progress killing bacteria recent years. Finally, paper further discusses existing challenges adjustment directions related to current research, providing guidance future nanoplatform.

Language: Английский

Nanoscale Prussian Blue and Its Analogues: Design and Applications in Infection Control, Wound Healing and Beyond

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(12), P. 1616 - 1616

Published: Dec. 20, 2024

Prussian blue nanoparticles (PBNPs) have gained significant attraction in the field of nanomedicine due to their excellent biocompatibility, potential for nanoscale production, exceptional photothermal conversion ability, and multi-enzyme mimicking capabilities. PBNPs made considerable advancements application biomedical fields. This review embarks with a comprehensive understanding physicochemical properties chemical profiling PB-based nanoparticles, discussing systematic approaches tune dimensions, shapes, sizes, as well properties. Subsequently, use NPs sector is extensively discussed categorized based on various features modified PBNPs, either combination drugs or analogues. Finally, article highlights existing challenges associated current studies explores latest developments these rapidly evolving nanoplatforms therapeutic potentials. Overall, this aims deepen provide crucial insights into rational design disease treatment.

Language: Английский

Bimodal Visual Sensors Based on Mechanoluminescence and Biosensing for Artificial Intelligence‐Assisted Orthodontics

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Abstract Flexible visual sensors hold great potential for application in wearable electronics and health monitoring. However, the separate acquisition of various signals without mutual interference their functional integration internal biomedical devices remains a significant challenge. Here, material that integrates mechanoluminescent units with biosensing through supramolecular interactions, enabling bimodal non‐interfering detection orthodontic force bacterial infection is presented. The induces fluorescence by facilitating release electrons from trapped energy levels, caused disruption or rearrangement defect structures within strontium aluminate crystals. Meanwhile, seamlessly integrated component can effectively detect lactic acid dose‐dependent manner, underscoring its multifunctional capabilities applications. Moreover, development cloud‐based deep learning server achieve 97.7% accuracy precise decoupling signals, remote monitoring early intervention during treatment. proposed artificial intelligence‐enhanced represent new paradigm monitoring, suitable wide range

Language: Английский