Biosensors, Journal Year: 2024, Volume and Issue: 14(12), P. 580 - 580

Published: Nov. 28, 2024

Point-of-care (POC) immunoassays have become convincing alternatives to traditional immunosensing methods for the sensitive and real-time detection of targets. Immunoassays based on gas-generating reactions were recently developed been used in various fields due their advantages, such as rapid measurement, direct reading, simple operation, low cost. Enzymes or nanoparticles modified with antibodies can effectively catalyze convert immunorecognition events into gas pressure signals, which be easily recorded by multifunctional portable devices. This article summarizes advances gas-generating-reaction-based immunoassays, according different types signal output systems, including distance-based readout, differential, visualized detection, thermal measurement. The review mainly focuses role photothermal materials working principle immunoassays. In addition, challenges prospects future development are briefly discussed.

Language: Английский