Enzyme-Instructed Interfacial Jamming of Pillar[5]arenes for Macroscopic Signal Amplification

Langmuir, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Enzyme-instructed signal generation at liquid-liquid interfaces presents a novel strategy for controlling and detecting biochemical processes on macroscopic scales. Here, we explore the self-assembly jamming of pillar[5]arene (P[5]A) derivatives oil-water interface via copper-mediated "click" reaction, providing versatile platform generating observable signals. The formation pillar[5]arenes network droplet reduces interfacial tension, allowing droplets to adopt various nonequilibrium shapes based process. By varying concentrations P[5]A ascorbic acid (AA), fine-tune surface coverage droplets, offering control over dynamics. Additionally, introduce amplification mechanism where dephosphorylation dormant reductant by alkaline phosphatase (ALP) triggers reaction interface. This system enables quantification ALP activity through changes with inhibition heavy metals metal chelators reducing coverage. approach represents promising method amplifying molecular signals into detectable outputs potential applications in sensing materials science.

Language: Английский

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Fabrication of imine-based COFs with different linker lengths for HRP and GOx immobilization and colorimetric detection of glucose and H2O2

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: 333, P. 125892 - 125892

Published: Feb. 12, 2025

Language: Английский

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Assembly of T4 Bacteriophages with Β-Galactosidase for Electrochemical Detection of Escherichia Coli K12

Published: Jan. 1, 2025

Language: Английский

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Synthesis innovations for crystallizing covalent organic framework thin films on biological and non-biological substrates

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Thin film technology has emerged as a pivotal field with numerous industrial applications. Depending on their properties-such magnetic characteristics, conductivity, architectural structure, stability, and functional backbones-thin films are widely utilized in optoelectronics, thin-film coatings, solar cells, energy storage devices, semiconductors, separation However, for all these applications, thin must be securely attached to specific substrates, substrate compatibility both the film-growth process is crucial optimal performance. In this review, we emphasize significance of growing films, particularly covalent organic framework (COF) suitable substrates tailored various For technologies, polymer commonly fabricated porous polymeric or metal-based membranes. contrast, metals metal oxides typically deposited conducting serving current collectors devices. Semiconductor other hand, often grown silicon glass transistor Emerging COF tunable properties, well-defined pore channels, versatile backbones, have demonstrated exceptional potential separation, storage, electronic optoelectronic interplay between well growth conditions, remains underexplored. Studies investigating such metals, oxides, glass, silicon, polymers, ITO, FTO provided insights into properties that promote superior growth. The quality formed significantly influences performance Additionally, discuss stabilization biological like peptide-based biomimetic catalysts enzymes, which suffer from instability non-aqueous environments, limiting use. Growing membranes can enhance stability under harsh conditions. We also highlight techniques ensuring preservation structural integrity properties.

Language: Английский

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Conjugated polymer/enzyme/silica hybrid capsules for lactate biosynthesis

Chemical Engineering Science, Journal Year: 2025, Volume and Issue: unknown, P. 121509 - 121509

Published: March 1, 2025

Language: Английский

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Biocatalytic nanofibrous membranes with enhanced self-cleaning properties through an in-situ ZIF-8 anchoring and trypsin incorporation strategy

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132808 - 132808

Published: April 1, 2025

Language: Английский

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Assembly of T4 bacteriophages with β-galactosidase for electrochemical detection of Escherichia coli K12

Food Chemistry, Journal Year: 2025, Volume and Issue: 484, P. 144399 - 144399

Published: April 17, 2025

Language: Английский

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Hierarchical MXene/Enzyme@Covalent Organic Framework Composite by Template Method for Photothermal‐Enhanced Lipase Catalysis

Small, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Abstract Enzyme immobilization has emerged as a promising strategy to facilitate the industrialization of biomolecules. However, immobilized systems are now still facing great challenges such maintaining enzyme activity, large‐scale manufacturing recovery and leaching or conformational changes enzymes. Therefore, advanced techniques (efficient, stable tunable catalysis) currently an important challenge in this field. Here, enzyme@cyclodextrin covalent organic framework films synthesized by template method further constructed three‐dimensional (3D) hydrogen bond‐enhanced efficient MXene/enzyme membrane reactor. This provides spacious microenvironment for release molecules, simpler process, easier‐to‐etch template, more biocompatible carrier. Furthermore, versatile platform interfacial photothermal fast mass‐transfer constructing with MXene. The obtained biocatalysts have excellent reusability, high activity stability, which can be used industrial reactions. reactor is ‘smart capsule ’ enzyme@cyclodextrin‐COF structure. solve challenging problems original previous system. Overall, new idea provided green, efficient, sustainable general catalytic platform.

Language: Английский

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Impact of Postsynthetic Modification on the Covalent Organic Framework (COF) Structures

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 21, 2024

Covalent organic frameworks (COFs) have emerged as a versatile class of materials owing to their well-defined crystalline structures and inherent porosity. In the realm COFs, appeal lies in customizable nature, which can be further enhanced by incorporating diverse functionalities. Postsynthetic modifications (PSMs) emerge potent strategy, facilitating introduction desired functionalities postsynthesis. A significant challenge PSM pertains preserving crystallinity porosity COFs. this study, we aim investigate intricate interplay between strategies resulting porous The investigation delves into methodologies employed PSMs, elucidate distinct influences on Through comprehensive analysis recent advancements case studies, study highlights relationships among parameters, including reaction conditions, precursor selection, functional groups, impact structural features By understanding how fine-tune characteristics researchers harness knowledge design COFs with tailored properties for specific applications, contributing advancement fields. This work not only deepens our but also provides valuable insights broader other solid materials.

Language: Английский

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A novel dual-function biomimetic approach for high throughput organic dye biodegradation and hydrogen peroxide sensing using a nanosized artificial peroxidase with ultra-improved substrate affinity and superb catalytic efficiency

Process Biochemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

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