Tuning Mn-MOF by Incorporating a Phthalocyanine Derivative as an Enzyme Mimic for Efficient EGFET-based Ascorbic Acid Detection DOI
Mallikarjuna Swamy Shabanur Matada, N. Venkatramaiah,

Surya Velappa Jayaraman

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 28, 2025

In this study, we present the effect of catalytic performance in Mn-MOF upon incorporating varied concentrations phthalocyanine derivative (H2PcP8OH16) for ascorbic acid detection an extended gate field-effect transistor (EGFET) configuration. The fabricated Mn-OM-MOF-2/CP electrode demonstrated notable selectivity toward physiological conditions sweat, with a sensitivity 71.375 μA·mM–1·cm–2, response time less than 6 s, and linear range from 5 to 240 μM. limit (LOD) quantification (LOQ) were found be 0.26 0.78 μM, respectively. Remarkably, prepared electrodes followed Michaelis–Menten kinetics. Among them, highest affinity acid, Km value 0.142 mM. To gain deeper insights into charge transfer mechanism during interaction Mn-OM-MOF-2/CP, employed scanning Kelvin probe (SKP) technique conducted post-FTIR analysis understand sensing mechanism. Additionally, post-UV–visible (UV–vis) measurements performed explore how incorporation enhances affinity. Additional studies using standard artificial sweat have confirmed electrode's good recovery. Overall, results EGFET method suitability rapid, noninvasive, single-use 1× phosphate buffer saline (1× PBS).

Language: Английский

Tuning Mn-MOF by Incorporating a Phthalocyanine Derivative as an Enzyme Mimic for Efficient EGFET-based Ascorbic Acid Detection DOI
Mallikarjuna Swamy Shabanur Matada, N. Venkatramaiah,

Surya Velappa Jayaraman

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 28, 2025

In this study, we present the effect of catalytic performance in Mn-MOF upon incorporating varied concentrations phthalocyanine derivative (H2PcP8OH16) for ascorbic acid detection an extended gate field-effect transistor (EGFET) configuration. The fabricated Mn-OM-MOF-2/CP electrode demonstrated notable selectivity toward physiological conditions sweat, with a sensitivity 71.375 μA·mM–1·cm–2, response time less than 6 s, and linear range from 5 to 240 μM. limit (LOD) quantification (LOQ) were found be 0.26 0.78 μM, respectively. Remarkably, prepared electrodes followed Michaelis–Menten kinetics. Among them, highest affinity acid, Km value 0.142 mM. To gain deeper insights into charge transfer mechanism during interaction Mn-OM-MOF-2/CP, employed scanning Kelvin probe (SKP) technique conducted post-FTIR analysis understand sensing mechanism. Additionally, post-UV–visible (UV–vis) measurements performed explore how incorporation enhances affinity. Additional studies using standard artificial sweat have confirmed electrode's good recovery. Overall, results EGFET method suitability rapid, noninvasive, single-use 1× phosphate buffer saline (1× PBS).

Language: Английский

Citations

0