Neuroprotective effects of biogenic silver nanoparticles in Parkinson's disease: In vitro and in vivo study DOI Creative Commons
Siren Zhao,

Jilun Zhang,

Jianbin Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138236 - 138236

Published: Dec. 1, 2024

The study aimed to develop immunomodulatory silver nanoparticles (CHT-PCT/AgNPs) using a green chemistry approach with Umbilicaria esculenta (U.E.) extract protect neurons from Parkinson's disease. synthesized CHT-PCT/AgNPs measured 88.2 ± 33.7 nm in size, zeta potential of approximately 24.5 1.9 mV. In vitro assays demonstrated that the green-synthesized exhibited greater biocompatibility and antioxidant properties compared chemically AgNPs. MTT assay indicated were cytocompatible up 50 μg/mL, but higher concentrations resulted significant toxicity. DPPH revealed dose-dependent activity, although it was lower than ascorbic acid. animal studies MPTP-induced Parkinsonism, count tyrosine hydroxylase (TH)-positive cells varied across groups, healthy controls showing 145.3 11.0 negative control group only 21.6 4.1. Additionally, number DRD1-positive also reflected similar trend. These findings suggest may serve as neuroprotective agent mitigate

Language: Английский

Plant-mimicking biodegradable nanofibers for enhanced PM capturing and AI-assisted high-accuracy respiratory diagnosis DOI
Xinjian He,

Yuyang Chen,

Haoran Sun

et al.

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: 361, P. 131459 - 131459

Published: Jan. 5, 2025

Language: Английский

Citations

6
Large-Scale Fabrication of 3D gradient hierarchical fibrous filter materials with Micro-Submicro-Nanofibers for efficient and Long-Duration air filtration DOI

Xu Zhao,

Yanru Bai,

Gaohui Fan

et al.

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: 362, P. 131867 - 131867

Published: Jan. 30, 2025

Language: Английский

Citations

2
High-efficiency respiratory protection and intelligent monitoring by nanopatterning of electroactive poly(lactic acid) nanofibers DOI

Liang Jiang,

Long Zhang, Xinjian He

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138769 - 138769

Published: Dec. 1, 2024

Language: Английский

Citations

4
Large-Scale Fabrication of 3d Gradient Hierarchical Fibrous Filter Materials with Micro-Submicro-Nanofibers for Efficient and Long-Duration Air Filtration DOI

Xu Zhao,

Yanru Bai,

Gaohui Fan

et al.

Published: Jan. 1, 2025

Atmospheric particulate matter pollution poses significant threats to human health and the environment. Submicron-fiber filtration materials have received widespread attention owing their ultrafine dimensions, high porosity, precise interception capabilities. However, low dust-holding capacity rapid resistance increase during use remain challenges. In this study, a modular helical linear free-surface multi-jet electrospinning device was employed prepare multi-scale fibers (80–800 nm) combine them with melt-blown non-woven fabrics in single-step process, creating three-dimensional gradient hierarchical material (3D-MNFG). The 3D-MNFG exhibits layered structure pore sizes transitioning from 18–32 μm 0.5–2.4 μm, 0.3–0.4 μm. Under an initial pressure decrease of 90 ± 3 Pa, it achieves efficiency (97%) quality factor 0.038 Pa−1, even after electrostatic treatment. Furthermore, novel overcomes limitations existing submicron-fiber membranes by offering dust holding 22.02 g/m2. dynamic tests at air velocities (28 m/s), its increased gradually, reaching lifespan limit (450 Pa) 29 d, significantly outperforming materials, which saturated within 8 d. Simulations validate synergistic mechanism micro/nano-fibers. fabricated shows promising potential for industrial production commercial applications.

Language: Английский

Citations

0
Impact of Stretching Conditions on Microstructure and Filtration Efficiency of ePTFE Membranes DOI Creative Commons
Yogita M. Shirke,

Dae-Hwan Kang,

Gyu Dong Lee

et al.

Chemical Engineering Journal Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100740 - 100740

Published: March 1, 2025

Language: Английский

Citations

0
Fully-biodegradable and self-powered intelligent filter assembled by fibrous cellulose and MOF-functionalized poly(lactic acid) core–shell nanofibers for active PM capturing and passive respiratory sensing DOI

Na Gao,

Yifan Zhang,

Ruizi Chen

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144118 - 144118

Published: May 1, 2025

Language: Английский

Citations

0
Neuroprotective effects of biogenic silver nanoparticles in Parkinson's disease: In vitro and in vivo study DOI Creative Commons
Siren Zhao,

Jilun Zhang,

Jianbin Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138236 - 138236

Published: Dec. 1, 2024

The study aimed to develop immunomodulatory silver nanoparticles (CHT-PCT/AgNPs) using a green chemistry approach with Umbilicaria esculenta (U.E.) extract protect neurons from Parkinson's disease. synthesized CHT-PCT/AgNPs measured 88.2 ± 33.7 nm in size, zeta potential of approximately 24.5 1.9 mV. In vitro assays demonstrated that the green-synthesized exhibited greater biocompatibility and antioxidant properties compared chemically AgNPs. MTT assay indicated were cytocompatible up 50 μg/mL, but higher concentrations resulted significant toxicity. DPPH revealed dose-dependent activity, although it was lower than ascorbic acid. animal studies MPTP-induced Parkinsonism, count tyrosine hydroxylase (TH)-positive cells varied across groups, healthy controls showing 145.3 11.0 negative control group only 21.6 4.1. Additionally, number DRD1-positive also reflected similar trend. These findings suggest may serve as neuroprotective agent mitigate

Language: Английский

Citations

1