Selenium Nanoparticles in Critical Illness—Anti-Inflammatory and Antioxidant Effects DOI Creative Commons
Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira

et al.

Dietetics, Journal Year: 2025, Volume and Issue: 4(1), P. 6 - 6

Published: Feb. 14, 2025

Selenium (Se) has important anti-inflammatory and antioxidant activities, plays an role in the immune system through redox balance, is part of selenoproteins. In patients who are critically ill, Se supplementation causes alterations inflammatory markers such as procalcitonin, leukocyte count, albumin, prealbumin, C-reactive protein (CRP), cytokines, cholesterol. The decrease levels leads to a reduction various selenoenzymes, particular glutathione peroxidase selenoprotein P. These selenoproteins play protective against lipoperoxidation cell membranes also participate process regulating response. Currently, there no conclusive data that allow us affirm existence significant mortality with use intensive care. nanoparticles (SeNPs) can be used dietary supplements or therapeutic agents due their low toxicity better bioavailability compared traditional supplementation. this review, we focus on current state research SeNPs properties therapy for seriously without toxic effects other species.

Language: Английский

Employing Copper-Based Nanomaterials to Combat Multi-Drug-Resistant Bacteria DOI Creative Commons

Yujie Zhai,

Zhiqing Liang, Xijun Liu

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 708 - 708

Published: March 21, 2025

The rise of multi-drug-resistant (MDR) bacteria poses a severe global threat to public health, necessitating the development innovative therapeutic strategies overcome these challenges. Copper-based nanomaterials have emerged as promising agents due their intrinsic antibacterial properties, cost-effectiveness, and adaptability for multifunctional approaches. These materials exhibit exceptional potential in advanced therapies, including chemodynamic therapy (CDT), photothermal (PTT), photodynamic (PDT). Their unique physicochemical such controlled ion release, reactive oxygen species (ROS) generation, tunable catalytic activity, enable them target MDR effectively while minimizing off-target effects. This paper systematically reviews mechanisms through which Cu-based enhance efficiency emphasizes specific performance field. Key factors influencing properties—such electronic interactions, characteristics, size effects, ligand single-atom doping, geometric configurations—are analyzed depth. By uncovering copper-based nanomaterials, this work aims inspire approaches that improve patient outcomes, reduce burden bacterial infections, health initiatives.

Language: Английский

Citations

0
Selenium Nanoparticles in Critical Illness—Anti-Inflammatory and Antioxidant Effects DOI Creative Commons
Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira

et al.

Dietetics, Journal Year: 2025, Volume and Issue: 4(1), P. 6 - 6

Published: Feb. 14, 2025

Selenium (Se) has important anti-inflammatory and antioxidant activities, plays an role in the immune system through redox balance, is part of selenoproteins. In patients who are critically ill, Se supplementation causes alterations inflammatory markers such as procalcitonin, leukocyte count, albumin, prealbumin, C-reactive protein (CRP), cytokines, cholesterol. The decrease levels leads to a reduction various selenoenzymes, particular glutathione peroxidase selenoprotein P. These selenoproteins play protective against lipoperoxidation cell membranes also participate process regulating response. Currently, there no conclusive data that allow us affirm existence significant mortality with use intensive care. nanoparticles (SeNPs) can be used dietary supplements or therapeutic agents due their low toxicity better bioavailability compared traditional supplementation. this review, we focus on current state research SeNPs properties therapy for seriously without toxic effects other species.

Language: Английский

Citations

0