Gadolinium-doped carbon dots with long-wavelength emission for dual-modal imaging DOI

Arina A. Efimova,

Zilya Badrieva, Ekaterina Brui

et al.

Journal of Optical Technology, Journal Year: 2024, Volume and Issue: 91(6), P. 362 - 362

Published: June 1, 2024

Subject of study . This is focused on luminescent carbon dots derived from o-phenylenediamine and gadolinium chloride or nitrate hexahydrate. Aim study. The aims to fabricate long-wavelength photoluminescent gadolinium-doped that could function as contrast agents for magnetic resonance imaging. Additionally, the investigates impact precursor type used chemical composition optical transitions resulting nanoparticles. Method. Carbon were synthesized using a one-step solvothermal method, their properties analyzed spectroscopy methods. Magnetic imaging was conducted clinical scanner with field strength 1.5 T. Main results. In this study, two types hexahydrate method. Metal doping, at concentration sufficient further investigations, achieved only when used. presence during synthesis leads formation centers within emission 600–720 nm photoluminescence quantum yield 6.3%. contrast, increases nitrogen content o-phenylenediamine-based while inhibiting metal doping. band an maximum 550 7.4% originates derivatives formed such dots. results also show alter relaxation times scanning, calculated relaxivity ( r 1 2 ) values are 6.4 38.6L⋅mmol −1 ⋅s , respectively. Thus, positive scanning. Practical significance. promising nanoprobes luminescence With these nanoparticles can be Consequently, based utilized dual-mode bioimaging.

Language: Английский

Nitrogen-doped carbon dots derived from ellagic acid and L-tyrosine for photothermal anticancer and anti-inflammation DOI

Xueli Ye,

Zhonghuan Qu,

Yuekai Wu

et al.

Biomaterials Advances, Journal Year: 2024, Volume and Issue: 163, P. 213951 - 213951

Published: July 4, 2024

Language: Английский

Citations

2

Microporous Fluorescent Poly(D,L-lactide) Acid–Carbon Nanodot Scaffolds for Bone Tissue Engineering Applications DOI Open Access
Nicolò Mauro, Giovanna Calabrese, Alice Sciortino

et al.

Materials, Journal Year: 2024, Volume and Issue: 17(2), P. 449 - 449

Published: Jan. 17, 2024

In this study, we introduce novel microporous poly(D,L-lactide) acid–carbon nanodot (PLA-CD) nanocomposite scaffolds tailored for potential applications in image-guided bone regeneration. Our primary objective was to investigate concentration-dependent structural variations and their relevance cell growth, crucial aspects The methods employed included comprehensive characterization techniques such as DSC/TGA, FTIR, rheological, degradation assessments, providing insights into the scaffolds’ thermoplastic behavior, microstructure, stability over time. Notably, PLA-CD exhibited distinct self-fluorescence, which persisted after 21 days of incubation, allowing detailed visualization various multicolor modalities. Biocompatibility assessments were conducted by analyzing human adipose-derived stem (hADSC) growth on scaffolds, with results substantiated through viability morphological analyses. hADSCs reached a 125% penetrated throughout scaffold incubation. These findings underscore regeneration fluorescence imaging. multifunctional nature nanocomposite, integrating diagnostic capabilities tunable properties, positions it promising candidate advancing tissue engineering. study not only highlights key investigation but also underscores specific application regeneration, foundation further research optimization critical biomedical field.

Language: Английский

Citations

1

Lanthanides and their complexes/nanoparticles: A review of cancer diagnosis, therapeutics, toxicity considerations, and clinical trials DOI
Tatenda Madanhire, Louis‐Charl C. Coetzee, Adedapo S. Adeyinka

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 106561 - 106561

Published: Dec. 1, 2024

Language: Английский

Citations

1

Blazing Carbon Dots: Unfolding its Luminescence Mechanism to Photoinduced Biomedical Applications DOI

Nirmiti Mate,

Vinita Satwani,

Pranav Tiwari

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract Carbon dots (CDs) are carbon‐based nanomaterials that have garnered immense attention owing to their exceptional photophysical and optoelectronic properties. They been employed extensively for biomedical imaging phototherapy due superb water dispersibility, low toxicity, outstanding biocompatibility, tissue permeability. This review summarizes the structural classification of CDs, CDs according precursor sources, luminescence mechanism CDs. The modification in via various doping routes is comprehensively reviewed, effect such alterations on properties, as absorbance, photoluminescence (PL), reactive oxygen species generation ability, also highlighted. strives summarize role cellular fluorescence lifetime metabolism. Subsequently, recent advancements future potential nanotheranostic agents discussed. Herein, we discussed photothermal, photodynamic, synergistic therapy anticancer, antiviral, antibacterial applications. overall summary highlights prospects CD‐based research bioimaging biomedicine.

Language: Английский

Citations

0

Gadolinium-doped carbon dots with long-wavelength emission for dual-modal imaging DOI

Arina A. Efimova,

Zilya Badrieva, Ekaterina Brui

et al.

Journal of Optical Technology, Journal Year: 2024, Volume and Issue: 91(6), P. 362 - 362

Published: June 1, 2024

Subject of study . This is focused on luminescent carbon dots derived from o-phenylenediamine and gadolinium chloride or nitrate hexahydrate. Aim study. The aims to fabricate long-wavelength photoluminescent gadolinium-doped that could function as contrast agents for magnetic resonance imaging. Additionally, the investigates impact precursor type used chemical composition optical transitions resulting nanoparticles. Method. Carbon were synthesized using a one-step solvothermal method, their properties analyzed spectroscopy methods. Magnetic imaging was conducted clinical scanner with field strength 1.5 T. Main results. In this study, two types hexahydrate method. Metal doping, at concentration sufficient further investigations, achieved only when used. presence during synthesis leads formation centers within emission 600–720 nm photoluminescence quantum yield 6.3%. contrast, increases nitrogen content o-phenylenediamine-based while inhibiting metal doping. band an maximum 550 7.4% originates derivatives formed such dots. results also show alter relaxation times scanning, calculated relaxivity ( r 1 2 ) values are 6.4 38.6L⋅mmol −1 ⋅s , respectively. Thus, positive scanning. Practical significance. promising nanoprobes luminescence With these nanoparticles can be Consequently, based utilized dual-mode bioimaging.

Language: Английский

Citations

0