Journal of Cleaner Production, Journal Year: 2025, Volume and Issue: unknown, P. 145917 - 145917
Published: June 1, 2025
Language: Английский
Journal of Cleaner Production, Journal Year: 2025, Volume and Issue: unknown, P. 145917 - 145917
Published: June 1, 2025
Language: Английский
Antibiotics, Journal Year: 2025, Volume and Issue: 14(2), P. 207 - 207
Published: Feb. 18, 2025
The rapid rise of antibiotic resistance has become a global health crisis, necessitating the development innovative strategies to combat multidrug-resistant (MDR) pathogens. Nanomaterials have emerged as promising tools in this fight, offering unique physicochemical properties that enhance efficacy, overcome mechanisms, and provide alternative therapeutic approaches. This review explores diverse nanomaterial-based used resistance, focusing on their mechanisms action practical applications. such metal nanoparticles, carbon-based nanomaterials, polymeric nanostructures exhibit antibacterial through various pathways, including generation reactive oxygen species (ROS), disruption bacterial membranes, enhancement delivery. Additionally, ability nanomaterials bypass traditional biofilm formation efflux pumps, been demonstrated numerous studies. also discusses synergistic effects observed when are combined with conventional antibiotics, leading increased susceptibility reduced required dosages. By highlighting recent advancements clinical applications nanomaterial-antibiotic combinations, paper provides comprehensive overview how reshaping future therapies. Future research directions challenges, toxicity scalability, addressed guide safer, more effective treatments.
Language: Английский
Citations
6Nanomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 18
Published: Jan. 31, 2025
Microbial infections are a pressing global health issue, exacerbated by the rise of antibiotic-resistant bacteria due to widespread antibiotic overuse. This resistance diminishes effectiveness current treatments, intensifying need for new antimicrobial agents and innovative drug delivery strategies. Nanotechnology presents promising solutions, leveraging unique properties nanomaterials such as tunable optical electronic characteristics, nanoscale size, high surface-to-volume ratios. These features enhance their versatile systems. minireview classifies into four categories based on mechanisms action: thermal generation, reactive oxygen species gas nanocarrier systems liposomes, polymersomes, metal-organic frameworks. Uniquely, this review integrates comparative analysis these mechanisms, highlighting relative advantages, limitations, applications across diverse microbial targets. Additionally, it identifies emerging trends in field, providing forward-looking perspective how recent advancements nanotechnology can be leveraged address unmet clinical needs. Finally, article discusses future directions opportunities nanotechnology.
Language: Английский
Citations
1BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)
Published: Feb. 3, 2025
Language: Английский
Citations
0Journal of Cleaner Production, Journal Year: 2025, Volume and Issue: unknown, P. 145917 - 145917
Published: June 1, 2025
Language: Английский
Citations
0