A Review on High Entropy Alloys as Metallic Biomaterials: Fabrication, Properties, Applications, Challenges, and Future Prospects DOI
Jaideep Adhikari,

Prerona Saha,

Pritam Mandal

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

In recent years, designing alloys with diverse elements or high entropy (HEAs) has received significant research interest for biomedical applications, particularly bone repair techniques that use materials excellent strength and biocompatibility. This review paper transitions from the core HEA concept to factors influencing cell-material interactions. The application area Bio-HEA was not only fixed orthopaedic implants; prospects in photothermal, bioimaging, biosensors, therapeutics have also been discussed. Another focus of this is identifying suitable can elucidate reduced toxicity enhanced antimicrobial activity. Critical discussions on lowering elastic modulus bio-HEAs provided mitigate stress-shielding effect-related implant rejection. Further, corrosion wear resistance their impact cellular functions Synthesis as a bulk material nuances nanoparticle discussed along entropy-based other systems applications. further delves into composite fabrication its applicability coating material. Concepts like strength-ductility trade-off, elemental alloy composition physical properties, strengthening mechanism, single-phase stability concepts were connection Bio-HEA. concludes by present challenges limiting clinical translation HEAs exploring future in-depth directions involving computational modelling advanced manufacturing optimize further.

Language: Английский

A new era for applications of multi-principal element alloys in the biomedical field DOI
Ao Wei,

Guijiang Diao,

Ruirui Dai

et al.

Biomaterials Advances, Journal Year: 2025, Volume and Issue: 172, P. 214244 - 214244

Published: Feb. 27, 2025

Language: Английский

Citations

0
A Review on High Entropy Alloys as Metallic Biomaterials: Fabrication, Properties, Applications, Challenges, and Future Prospects DOI
Jaideep Adhikari,

Prerona Saha,

Pritam Mandal

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

In recent years, designing alloys with diverse elements or high entropy (HEAs) has received significant research interest for biomedical applications, particularly bone repair techniques that use materials excellent strength and biocompatibility. This review paper transitions from the core HEA concept to factors influencing cell-material interactions. The application area Bio-HEA was not only fixed orthopaedic implants; prospects in photothermal, bioimaging, biosensors, therapeutics have also been discussed. Another focus of this is identifying suitable can elucidate reduced toxicity enhanced antimicrobial activity. Critical discussions on lowering elastic modulus bio-HEAs provided mitigate stress-shielding effect-related implant rejection. Further, corrosion wear resistance their impact cellular functions Synthesis as a bulk material nuances nanoparticle discussed along entropy-based other systems applications. further delves into composite fabrication its applicability coating material. Concepts like strength-ductility trade-off, elemental alloy composition physical properties, strengthening mechanism, single-phase stability concepts were connection Bio-HEA. concludes by present challenges limiting clinical translation HEAs exploring future in-depth directions involving computational modelling advanced manufacturing optimize further.

Language: Английский

Citations

0