Preparation of Antibacterial and Antiadhesive Urinary Catheters with Robust Double-Network Gelatin-Polyacrylamide-Ag Nanoparticle Hydrogel Coatings
Yongwei Cai,
No information about this author
Jianxiang Li,
No information about this author
Ronghua Gu
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et al.
ACS Applied Polymer Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 13, 2025
Urinary
catheter
surfaces
are
susceptible
to
bacterial
contamination,
contributing
catheter-associated
urinary
tract
infections
(CAUTIs).
Although
hydrogel
coatings
have
exhibited
potential
in
preventing
bacteria
adhesion
and
biofilm,
they
frequently
experience
poor
bond
strength
with
substrates
weak
mechanical
properties,
leading
delamination
or
fracture
during
clinical
use.
In
this
paper,
we
developed
a
robust
double
network
gelatin-polyacrylamide
(PAAm)-Ag
nanoparticle
(GPA-0.01)
coating
on
Foley-type
double-lumen
medical
latex
catheters
(UCs).
The
study
revealed
that
the
GPA-0.01
slow
swelling
ratio,
strong
structural
stability,
excellent
rheological
ensuring
durability
of
hydrogel-coated
UCs
even
under
harsh
conditions.
Furthermore,
displayed
exceptional
hydrophilic
lubricating
along
various
substrates.
More
importantly,
demonstrated
significant
antibacterial
effects
against
Gram-negative
Escherichia
coli
both
outer
lumen
(inner)
surfaces,
as
well
antiadhesion
properties
could
potentially
reduce
CAUTIs.
Additionally,
showed
cytocompatibility
blood
compatibility
vitro.
proposed
antibiofouling
property
was
attributed
synergistic
effect
PAAm
gelatin
long-lasting
linked
gradual
release
silver
nanoparticles.
Overall,
demonstrates
addressing
resistance
CAUTIs,
promising
applications
for
sustained
biomedical
devices.
Language: Английский
Bionic sustainable superhydrophobic coating featuring high durability, antifouling, and anticorrosion properties
Progress in Organic Coatings,
Journal Year:
2025,
Volume and Issue:
204, P. 109264 - 109264
Published: April 4, 2025
Language: Английский
Research on underwater air layer retention and antifouling ability of Salvinia-inspired biomimetic materials
Colloids and Surfaces B Biointerfaces,
Journal Year:
2025,
Volume and Issue:
253, P. 114728 - 114728
Published: April 24, 2025
Language: Английский
A Review on Recently Developed Antibacterial Composites of Inorganic Nanoparticles and Non-Hydrogel Polymers for Biomedical Applications
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(21), P. 1753 - 1753
Published: Oct. 31, 2024
Development
of
new
antibacterial
materials
for
solving
biomedical
problems
is
an
extremely
important
and
very
urgent
task.
This
review
aims
to
summarize
recent
articles
(from
the
last
five
mostly
three
years)
on
nanoparticle/polymer
composites
applications.
Articles
polymeric
nanoparticles
(NPs)
hydrogel-based
systems
were
not
reviewed,
since
we
focused
our
attention
matrix
with
at
least
one
inorganic
filler
in
form
NPs.
The
fields
application
newly
developed
NPs/polymer
are
described,
along
their
composition
synthetic
approaches
that
allow
researchers
succeed
preparing
effective
composite
medical
healthcare
purposes.
Language: Английский
Recent Progress in Antibacterial Surfaces for Implant Catheters
Shifang Luan,
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Jia Hu,
No information about this author
Qing Yu
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et al.
BME Frontiers,
Journal Year:
2024,
Volume and Issue:
6
Published: Sept. 9, 2024
Catheter-related
infections
(CRIs)
caused
by
hospital-acquired
microbial
lead
to
the
failure
of
treatment
and
increase
mortality
morbidity.
Surface
modifications
implant
catheters
have
been
demonstrated
be
effective
approaches
improve
largely
reduce
bacterial
colonization
related
complications.
In
this
work,
we
focus
on
last
5-year
progress
in
surface
biomedical
prevent
CRIs.
Their
antibacterial
strategies
used
for
are
further
divided
into
5
classifications
through
antimicrobial
mechanisms,
including
active
surfaces,
passive
combination
stimulus-type
response
other
types.
Each
feature
latest
advances
these
abovementioned
surfaces
highlighted.
Finally,
confronting
challenges
future
prospects
discussed
catheters.
Language: Английский
Innovative Polymeric Coatings with Dual Antifouling and Light-Activated Bactericidal Functions for Urinary Catheter Applications
Po-Hsun Chen,
No information about this author
GuanHua Chen,
No information about this author
Wei‐Bor Tsai
No information about this author
et al.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(21), P. 2974 - 2974
Published: Oct. 24, 2024
Catheter-associated
urinary
tract
infections
(CAUTIs)
present
significant
health
risks
in
medical
settings,
necessitating
innovative
solutions
to
prevent
bacterial
colonization
on
catheter
surfaces.
This
study
introduces
a
novel
polymeric
coating
with
dual
antifouling
and
light-activated
bactericidal
properties
enhance
the
efficacy
of
catheters.
The
coatings
were
synthesized
using
one-step
process
involving
pyrogallol
chemistry
deposit
copolymer
composed
zwitterionic
sulfobetaine
for
sodium
copper
chlorophyllin,
photosensitizer
that
generates
reactive
oxygen
species
under
light
exposure
effectively
kill
bacteria.
We
evaluated
properties,
cytocompatibility,
performance
various
conditions.
results
showed
reductions
adhesion,
activation
further
endowing
effects.
Additionally,
could
be
delivered
through
an
optical
fiber
within
lumen
target
action
offers
promising
approach
preventing
CAUTIs,
representing
potential
breakthrough
developing
safer
more
effective
Language: Английский