3D bioprinted GelMA scaffolds for clinical applications: promise and challenges DOI
Soumitra Das, Remya Valoor, Jeyapriya Thimukonda Jegadeesan

et al.

Bioprinting, Journal Year: 2024, Volume and Issue: unknown, P. e00365 - e00365

Published: Oct. 1, 2024

Language: Английский

3D Printing of a Self-Healing, Bioactive, and Dual-Cross-Linked Polysaccharide-Based Composite Hydrogel as a Scaffold for Bone Tissue Engineering DOI
Saba Nasiripour, Fatemehsadat Pishbin, S.A. Seyyed Ebrahimi

et al.

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Although 3D printing is becoming a dominant technique for scaffold preparation in bone tissue engineering (TE), developing hydrogel-based ink compositions with bioactive and self-healing properties remains challenge. This research focuses on based composite hydrogel, which maintains its after incorporating glass 3D-printable. The plain hydrogel was synthesized using natural polymers of 1 wt % N-carboxyethyl chitosan, 2 hyaluronic acid aldehyde, 0.3 adipic hydrazide, alginate (ALG) (2, 5, 10 %). Bioactive (BG) (0 5 w/v %) particles were incorporated into the matrix to obtain an osteogenic hydrogel. material characterized via rheology, field emission scanning electron microscopy/energy-dispersive X-ray spectroscopy (FESEM/EDS), Fourier transform infrared (FTIR) spectroscopy, diffraction (XRD), swelling, degradation, bioactivity, vitro cellular assessments. Rheological evaluations confirmed that specimen 0 BG ALG exhibited highest G', G″, viscosity values. All specimens self-healing, provided by two reversible dynamic bonds, namely, imine acylhydrazone. Bioactivity evaluation SBF immersion revealed formation HA hydrogels. MTT cytotoxicity assay MG63 indicated sample containing had cell viability (95 ± 1.02%) culture day 3. developed approach presents promising formulation high potential extrusion-based TE constructs.

Language: Английский

Citations

1
High-strength and excellent biological activity of modified tricalcium silicate/bioglass composite bone cement for biomaterials DOI
Yin Zhang, Zilong Zhang,

Qiuli Fang

et al.

Ceramics International, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Phase-adapted Metal Ion Supply for Spinal Cord Repair with a Mg-Zn Incorporated Chimeric Microsphere DOI
Xiangyu Liu,

Biao Ma,

S L Hu

et al.

Biomaterials, Journal Year: 2025, Volume and Issue: 320, P. 123253 - 123253

Published: March 11, 2025

Language: Английский

Citations

0
Dual Crosslinkable Gelatin Glycidyl Methacrylate-based Hydrogel: Key Insights to Biophysical Properties and Applicability Towards 3D Printing DOI

Garga Mondal,

Sulob Roy Chowdhury,

Priyanka Paul

et al.

Regenerative Engineering and Translational Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

Language: Английский

Citations

0
3D bioprinted GelMA scaffolds for clinical applications: promise and challenges DOI
Soumitra Das, Remya Valoor, Jeyapriya Thimukonda Jegadeesan

et al.

Bioprinting, Journal Year: 2024, Volume and Issue: unknown, P. e00365 - e00365

Published: Oct. 1, 2024

Language: Английский

Citations

2