The
selective
modification
of
unprotected
carbohydrates
for
cross-linking
in
waterborne
coatings.As
you
all
know
we
use
a
lot
plastic
and
polymers.
There
are
big
problems
with
since
they
oil
based
produce
waste.
That
way
contribute
to
the
problem
global
heating
because
their
carbon
footprint.Also
coatings
such
polymers
used
protect
our
metal
wooden
surfaces.
Even
though
do
not
end
up
same
as
waste,
help
footprint.
New
inventions
tried
but
often
expensive
difficult
make.What
if
there
already
was
cheap
green
alternative
“old
oil-based
plastics
polymers”?
Indeed,
it
is
possible
take
plant-based
feedstocks
production
Moreover,
even
organic
waste
feedstocks,
e.g.
from
industry
form
crap
shells.Most
these
have
common,
that
built
large
chains
sugar
molecules,
so-called
polysaccharides.
These
polysaccharides
perfect
starting
materials
alternatives
polymerized
into
consist
number
functionalities.
Functionalities
necessary
perform
further
chemistry
modify
chains’
properties.The
whole
process
modifying
bio-waste
feedstock
only
an
opportunity
also
challenge.
goal
aqueous
solutions
so
no
toxic
solvents
needed.
applies
reagents
modifications.
It
example
catalysts
contain
heavy
metals.This
where
ARC
CBBC
started
its
flagship
project
coatings.
Coatings
general
just
protective
layer
made
plastic.My
part
this
handle
afterwards,
which
can
be
cross-link
onto
each
other.
will
make
water-soluble
material
water-resistant
coating
after
drying
(comparison
between
spaghetti
lasagna).
ACS Catalysis,
Journal Year:
2024,
Volume and Issue:
unknown, P. 17727 - 17738
Published: Nov. 18, 2024
We
demonstrate
an
efficient,
scalable,
and
stereoselective
C-glycosylation
with
thioglycosides
possessing
a
unique
photoactive
tetrafluoropyridin-4-yl
(TFPy)
thio
radical
leaving
group,
affording
editable
medicinally
biologically
essential
C-α-glucogallin
derivatives.
In
the
presence
of
silyl
enol
ether
acceptors,
desulfurative
coupling
reaction
performs
smoothly
under
mild
conditions
upon
exposure
to
blue
light
irradiation.
This
versatile
protocol
permits
synthesis
sugar-drug
chimeras
by
C1
ketonylation
complex
drug-derived
ethers.
The
scale-up
synthesis,
anomeric
epimerization,
post-C-glycosylation
modification
ketone
sugars
showcase
reaction's
potential
utilities.
Furthermore,
could
be
applied
direct
carbohydrate
skeleton
editing
equipping
group
on
nonanomeric
position.
is
viable
for
unprotected
TFPy
thioglycoside,
route
ketonyl
sugars.
concise
six-step
assembly
both
configurated
C-glucogallins
from
commercially
cheap
glucose
pentaacetate
their
antioxidant
reactivity
investigations
underline
promising
medicinal
relevance
our
current
protocols.
mechanism
was
investigated
through
trapping
experiment,
oxocarbenium
fluorescence
quenching
Stern–Volmer
analysis,
confirming
that
major
glycosyl
intermediates
are
generated
thioglycoside
donors,
whose
effectively
quench
excited
Ir(ppy)3
oxidative
process,
complementary
product,
accounting
examples
moderate
selectivities.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(48), P. 6174 - 6177
Published: Jan. 1, 2024
The
electro-generation
of
acyl
radicals
from
both
aromatic
and
aliphatic
aldehydes
is
a
synthetic
challenge.
We
addressed
this
challenge
by
merging
electro-oxidation
quinuclidine-mediated
HAT
strategy.
ChemElectroChem,
Journal Year:
2023,
Volume and Issue:
10(22)
Published: Oct. 19, 2023
Abstract
The
site‐selective
transformation
of
unprotected
sugars
poses
significant
challenges
to
synthetic
chemists
but
comes
with
a
reward
step‐economic
and
energy
efficient
protocols.
By
replacing
stoichiometric
oxidants
electricity,
greener
processes
are
anticipated.
To
date,
mostly
C3‐
C6‐selective
transformations
have
been
developed
urging
for
further
developments.
Herein,
we
call
action
tackle
the
associated
toward
challenging
C2
C4
regioisomers
fueled
by
mild
electroorganic
transformations.
Nachrichten aus der Chemie,
Journal Year:
2024,
Volume and Issue:
72(3), P. 44 - 67
Published: Feb. 29, 2024
Abstract
Unter
anderem
das
hat
die
Organik
im
letzten
Jahr
bewegt:
milde
Oxidation
mit
Elektrochemie,
zu
enantiomerenreinen
Sulfonylverbindungen,
Flüssigkristallphasen
erkennen
maschinellem
Lernen,
CO
2
reagiert
Succinat
und
Carbamaten,
eine
Alternative
Bisphenol
A,
Subporphyrine,
photoschaltbare
Spinmaterialien,
photochemische
Thiophen‐Ringerweiterung,
Peptide
werden
Bor
versehen
cyclisiert.
Die
Zusammenstellung
des
Trendberichts
koordiniert
Martin
Breugst,
Universität
Chemnitz.
ChemSusChem,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 8, 2024
As
an
important
sustainable
method
for
chemical
synthesis,
organic
electrosynthesis
experienced
a
renaissance
in
recent
years
its
excellent
atom
economy.
Although
microchannel
reactors
have
been
proposed
to
advanced
devices
obtain
low
energy
cost
and
high
reaction
performance,
the
complex
multiphasic
flow
electrochemical
microchannels
are
very
less
reported
effects
of
condition
on
reported.
Taking
tetraethyl
thiuram
disulfide
(TETD)
as
typical
case,
we
developed
visualized
reactor
equipped
with
fluorine-doped
tin
oxide
(FTO)
loaded
glass
electrode
investigate
gas-liquid-liquid
triple
phase
pattern
main
factors
influenced
response
current
at
certain
applied
cell
voltage.
The
hybrid
gas
hold-up
liquid
rate
was
found
crucial
preventing
coverage
TETD
electrode,
which
provided
23.1
%
attenuation
ratio
3.0
V
research
not
only
exhibited
evolution
mechanism
current,
but
also
showed
importance
control
balancing
work
efficiency
consumption
process.
ChemCatChem,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 3, 2024
Abstract
The
quinuclidine
(Qu)‐catalyzed
activation
of
acylhydrazines
to
afford
the
corresponding
acyl
radicals
remains
an
unmet
challenge.
To
address
this
challenge,
we
report
a
synergistic
strategy
by
combining
electro‐oxidation
with
Qu‐based
HAT
catalysis.
Enabled
strategy,
electrochemical
Minisci
acylation
N
‐heterocycles
was
realized
for
first
time.
