Rh(iii)-catalyzed selective C2 C–H acyloxylation of indoles DOI
Chaoying Fang, Li Li, Hai‐Tao Yang

et al.

Chemical Communications, Journal Year: 2023, Volume and Issue: 60(2), P. 216 - 219

Published: Dec. 1, 2023

Herein, we present the first highly regio- and chemoselective C2 C-H acyloxylation of indole under rhodium catalysis an N-quinolinyl auxiliary. This strategy accommodates a wide range indoles structurally diverse carboxylic acids with good reaction efficiencies to yield functionalized indoles. The utility this logic was demonstrated by concise synthesis 2-oxindole derivatives. Preliminary mechanistic studies indicate that catalyst turnover RhIII-RhIV/V-RhII/III-RhIII might be involved in catalytic transformation.

Language: Английский

Electrooxidative iridium-catalyzed sp2 C−H activation-annulation leading to cationic π-extended heteroaromatics DOI
Qi‐Liang Yang, Nana Guo,

Shu-Xian Liu

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(17), P. 4849 - 4856

Published: Jan. 1, 2024

An electrochemically driven, Cp*Ir( iii )-catalyzed method for alkenyl and aromatic C(sp 2 )–H activation coupling with alkynes the synthesis of biologically useful quaternary ammonium salts under mild conditions is demonstrated.

Language: Английский

Citations

3
Rh(iii)-catalyzed selective C2 C–H acyloxylation of indoles DOI
Chaoying Fang, Li Li, Hai‐Tao Yang

et al.

Chemical Communications, Journal Year: 2023, Volume and Issue: 60(2), P. 216 - 219

Published: Dec. 1, 2023

Herein, we present the first highly regio- and chemoselective C2 C-H acyloxylation of indole under rhodium catalysis an N-quinolinyl auxiliary. This strategy accommodates a wide range indoles structurally diverse carboxylic acids with good reaction efficiencies to yield functionalized indoles. The utility this logic was demonstrated by concise synthesis 2-oxindole derivatives. Preliminary mechanistic studies indicate that catalyst turnover RhIII-RhIV/V-RhII/III-RhIII might be involved in catalytic transformation.

Language: Английский

Citations

2