Mechanisms of C(sp3)–H and C=C selective oxidative heterofunctionalizations by non-heme Fe and Mn mimics of oxygenase enzymes

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 508, P. 215793 - 215793

Published: March 18, 2024

Language: Английский

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Chiral Bis-8-Aryl-isoquinoline Bis-alkylamine Iron Catalysts for Asymmetric Oxidation Reactions

Organic Letters, Journal Year: 2025, Volume and Issue: 27(4), P. 1078 - 1083

Published: Jan. 22, 2025

A novel class of bis-8-aryl-isoquinoline (AriQ) bis-alkylamine iron complexes, FeII(AriQ2dp)(OTf)2 and FeII(AriQ2mc)(OTf)2 (dp = dipyrrolidinyl or mc N,N′-dimethylcyclohexyl-diamine), for asymmetric oxidation reactions is reported. The scalable divergent synthesis 8-aryl-3-formylisoquinolines (8), the key intermediates in preparing these ligands, enables precise structural electronic tuning around metal center. enantioselective epoxidation hydroxy carbonylation conjugated alkenes, mediated by FeII(3,5-di-CF3iQ2dp) catalyst with H2O2 as oxidant, demonstrates potential redox FeII[N4] catalysts inducing face selection oxygen transfer transformations.

Language: Английский

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Highly Position- and Enantioselective Catalytic Epoxidation of Polyolefins Mediated by a Chiral Mn Complex, Including a One-Step Conversion of Squalene to the (S)-2,3-Epoxide, a Precursor of Natural Steroids and Terpenoids

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: 147(2), P. 1448 - 1451

Published: Jan. 6, 2025

Reported herein is the synthesis of a novel chiral dicarboxylic ligand for Mn(II) and application Mn complex to highly enantio- position-selective epoxidation C═C under mild conditions, even with polyolefinic substrates. A stereomechanistic basis asymmetric induction suggested.

Language: Английский

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Visible Light-Mediated Co(II) Catalyzed Synthesis of α,β-Epoxy Ketones by Oxidative Coupling of Alkenes and Aldehydes in Water

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

A one-step, two-component visible light-mediated CoCl

Language: Английский

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Recent Advances in Nonprecious Metal Catalysis

Organic Process Research & Development, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 7, 2024

As the field of nonprecious metal catalysis continues to expand, we pursue a review series covering selected transformations in this area over short time interval highlight practical advancements. We seek raise awareness both current art and need continue development toward broader applications earth-abundant metals chemical pharmaceutical industries.

Language: Английский

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Nonheme Fe Based Enzyme Mimics for Fine Organic Synthesis: Catalytic C−H and C=C Oxygenations

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(40)

Published: July 8, 2024

Abstract Since the milestone contribution by Chen and White in 2007, bioinspired non‐heme bis ‐amino‐ ‐pyridylmethyl Fe complexes have been at forefront of studies related to designing catalytic approaches for direct oxidative functionalization aliphatic C−H bonds. This, however, has not developed into large‐scale synthetic applications date. The present concept is aimed briefly discussing state‐of‐the‐art catalyzed oxidations organic molecules with H 2 O , current oxidant choice oxidation catalysis, mostly focusing on oxidations, analyzing peculiarities their reactivity through prism potential fine synthesis.

Language: Английский

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Three-membered ring systems

Progress in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 41 - 58

Published: Jan. 1, 2024

Language: Английский

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