Ligand-Enabled “Two-in-One” Metallaphotocatalytic Cross Couplings

ACS Catalysis, Journal Year: 2025, Volume and Issue: 15(3), P. 1635 - 1654

Published: Jan. 15, 2025

Metallaphotoredox cross coupling (MCC) is ranking among the most advanced synthetic methodology as it can access chemical space that difficult to attain under conventional conditions. Earlier developed MCC mandates an independent transition metal catalyst and respective photocatalyst, thus constituting a dual catalytic manifold. Complementarily, paradigm-shifting metallaphotoredox strategy capitalizes on single photoreactive complex emerging, which brings not only operational simplification but also unexpected mechanistic insights. This perspective compiled recent advances in monocatalytic couplings categorized them based ligands confer distinct photoreactivities various mechanisms. To this end, ligand-enabled oxidative addition, transmetalation, reductive elimination other radical-involving pathways were summarized with notable examples. In way, we wish provide handy guideline for readers who are interested emerging field inspire more future endeavors MCCs beyond.

Language: Английский

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Confining polyoxometalates in porphyrin-based porous cationic polymer toward boosting visible-light-driven synthesis of sulfoxides and detoxification of mustard gas simulants

Journal of Catalysis, Journal Year: 2024, Volume and Issue: 436, P. 115627 - 115627

Published: July 1, 2024

Language: Английский

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Gold‐Catalyzed Alkyne‐Amine Cascade Annulations: A Modern Strategy for Azaheterocycle Construction

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Abstract Gold catalysis has experienced remarkable progress over the past two decades, particularly in transformations involving alkynes. While numerous aspects of gold‐catalyzed reactions have been extensively reviewed, specific area cascade annulations between functionalized amines and alkynes represents a distinct rapidly developing direction that warrants focused attention. This survey collects systematically analyzes these transformations, which emerged as convenient synthetic strategies to diverse nitrogen heterocycles. The relevant are classified firstly by chemical nature amine functional substituent, secondly size formed ring. field under consideration bridges several fundamental practical branches chemistry, including catalysis, organic synthesis, medicinal materials science.

Language: Английский

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A Halide-Induced Redox-Switchable Catalyst for the Hydroboration of Terminal Alkenes

Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

We describe the synthesis of two rhodium and iridium complexes featuring a di-NHC macrocyclic ligand, which incorporates both diphenylene moiety naphthalenediimide (NDI) unit. observed that addition fluoride or chloride resulted in substantial alterations to steric electronic properties complexes. Specifically, led reduction NDI unit through formation an (OH-) intermediate, while produced (Cl-)···NDI adduct. Both adducts were confirmed by mass spectrometry. The impact on NDI-containing was examined using spectroscopic computational methods. presence either halide significantly enhanced catalytic activity hydroboration terminal alkenes. Finally, we demonstrated this enhancement is reversible, with process being activated deactivated sequential introduction excess NOBF4. This observation reveals rare example halide-induced redox-switchable (HIRSC) system.

Language: Английский

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Azide as a photolabile ligand in gold(I) therapeutics

Journal of Organometallic Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 123724 - 123724

Published: May 1, 2025

Language: Английский

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Gold(i) complexes as powerful photosensitizers – a visionary frontier perspective

Dalton Transactions, Journal Year: 2024, Volume and Issue: 53(33), P. 13716 - 13725

Published: Jan. 1, 2024

Singlet oxygen production and its reactivity have significant implications in fields ranging from polymer science to photodynamic therapy. Extensive research has focused on the development of organic-based materials heavy metal complexes, including Ru(II), Rh(III), Ir(III) Pt(II). However, complexes containing Au(I) been scarcely explored warrant further investigation. This review provides a comprehensive analysis reported compounds, classified based ligands coordinated gold(I) centre. Additionally, future directions photosensitizer singlet applications are discussed.

Language: Английский

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Photooxidative Reaction of β-Oxoamides with Amines for the Synthesis of Pyrrolin-4-ones under External Photocatalyst-Free Conditions

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(14), P. 9972 - 9978

Published: July 2, 2024

The incorporation of oxygen atoms from air under aerobic conditions plays an important role in organic synthesis. Herein, Brønsted acids are found to be a two-in-one strategic catalyst transform enamines β-oxoamides and amines pyrrolin-4-ones without external photocatalyst visible-light conditions. acid can inhibit the C-C bond fragmentation [2 + 2] adduct enamine

Language: Английский

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