Three-component cascade carbopalladation/Heck cyclization/borylation: facile access to boryl-functionalized indenes

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(62), P. 8075 - 8078

Published: Jan. 1, 2024

A mild Pd-catalyzed three-component cascade cyclization functionalization of

Language: Английский

Zinc‐Mediated Carbamoyl Amination of Alkylidenecyclopropane‐Tethered Carbamoyl Chlorides: Synthesis of Functionalized 2‐Quinolones

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(22), P. 4644 - 4648

Published: Aug. 20, 2024

Abstract The transition metal catalyzed cyclization of alkene‐tethered carbamoyl chloride has emerged as a tool to construct oxindoles bearing quaternary centers. Most these reactions proceed via carbometalation‐initiated 5‐ exo ‐trig followed by nucleophilic trapping the resulting σ alkyl‐metal species achieve diverse functionalized oxindoles. 6‐ endo type been rarely reported. Herein, zinc‐mediated amination alkylidenecyclopropane‐tethered chlorides with anilines for synthesis 2‐quinolones was developed. A range different substituted were prepared in 65–89% yield from and aniline derivatives using Zn/TMSCl system.

Language: Английский

CCC pincer Ru complex-catalyzed C–H vinylation/6π-E-cyclization of aldimines for constructing 4H-pyrido[1,2-a]pyrimidines

Chemical Science, Journal Year: 2024, Volume and Issue: 15(39), P. 16216 - 16221

Published: Jan. 1, 2024

A convenient and efficient approach to construct a series of N -heteropolycycles using unique CCC pincer NHC–Ru( iii )-catalyzed cascade C–H vinylation/6π-electrocyclization pyridyl aldimines with unactivated vinyl bromides/triflates is reported.

Language: Английский