Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
The first manganese-catalyzed three-component coupling between secondary alcohol, allylic and phosphine via borrowing hydrogen is described. This four-stage, one-pot reaction afforded ε-hydroxy phosphines in a step-economical fashion.
Language: Английский
Organic Letters, Journal Year: 2024, Volume and Issue: 26(27), P. 5788 - 5793
Published: June 27, 2024
Stereocontrolled oxa-Michael additions are challenging, given the high reversibility of process, which ultimately leads to racemization newly formed stereocenters. When iron-catalyzed borrowing hydrogen from allylic alcohols was combined with a stereocontrolled organocatalytic addition, wide array chiral tetrahydropyrans were efficiently prepared. The reaction could be performed in diastereoselective manner pre-existing stereocenters or enantioselectively achiral substrates. key success reactivity iron complex, selective for alcohol dehydrogenation and irreversibly led final product.
Language: Английский
Citations
6
ChemCatChem, Journal Year: 2024, Volume and Issue: unknown
Published: July 2, 2024
Abstract In the quest for more rapid and eco‐compatible preparation of complex molecules from widely available ones, borrowing hydrogen is one most elegant manners to directly functionalize alcohols. Such catalytic cycles reduce synthetic cost, avoid waste additional steps associated with adjusting redox state functionalization carbon chains. this field, last ten years have seen development general strategies control absolute stereochemistry created molecules. This enantiocontrol can arise three distinct cycle, namely initial dehydrogenation, carbonyl or final back‐transfer. review presents different enantioselective approaches developed according these principles highlights great potential transformations, current limitations future challenges.
Language: Английский
Citations
4
ACS Omega, Journal Year: 2025, Volume and Issue: 10(9), P. 9649 - 9660
Published: Feb. 24, 2025
Construction of a C-C bond via alkylation ketones with alcohol as the alkylating source by employing hydrogen-borrowing strategy is attracting significant attention and highly appealing due to its simplicity, cost-effectiveness, environmental benefits, fact that water only byproduct. The development heterogeneous catalysts based on nonprecious base metals progressing rapidly. Our newly disclosed manganese-doped cerium oxide nanocomposite (10 wt % Mn@CeO2) stands out cost-efficient air-stable catalyst, synthesized through straightforward coprecipitation method employed for α-alkylation primary alcohols strategy. X-ray diffraction (XRD) analysis confirms high crystallinity CeO2, while field emission scanning electron microscopy (FE-SEM) high-resolution transmission (HR-TEM) images reveal MnO2 nanoparticles, measuring 19 nm in size, uniformly decorated rod-shaped CeO2 which have size 33 nm. photoelectron spectroscopy (XPS) uncovers presence Mn4+ species embedded nanorods. Electron paramagnetic resonance (EPR) further indicates surface defects contribute impressive catalytic yield, ranges from 70 98% α-alkylated ketones. Thermogravimetric (TGA) demonstrates remarkable thermal stability maintaining up 800 °C. Additionally, inductively coupled plasma mass spectrometry (ICP-MS) no leaching Mn ions, emphasizing heterogeneity catalyst. Remarkably, 10 Mn@CeO2 recycled six cycles loss activity. This study underscores synergistic effect between metal redox pair key exceptional activity reactions, making promising catalyst sustainable efficient formation.
Language: Английский
Citations
0
Trends in Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 1, 2025
Language: Английский
Citations
0
Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
The first manganese-catalyzed three-component coupling between secondary alcohol, allylic and phosphine via borrowing hydrogen is described. This four-stage, one-pot reaction afforded ε-hydroxy phosphines in a step-economical fashion.
Language: Английский
Citations
1