Highly Efficient One-Pot Synthesis of 2,4,5-Trisubstituted 3(2H)-Furanones Utilizing a Au(I)-Catalyzed Oxidation/Pinacol Rearrangement/anti-Michael Cascade DOI

Yanbin Wu,

Shuang Zang,

Hang Ren

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(36), P. 7656 - 7660

Published: Sept. 3, 2024

A highly efficient Au(I)-catalyzed cascade reaction between bispropargylic alcohols and pyridine-

Language: Английский

Enantioselective Cascade Annulation of 1,2,3-Triazoles and Enals Enabled by Sequential Rhodium and Oxidative NHC Catalysis Involving Cleavage, Migration, and Cyclization DOI

Xiaoyi Yu,

Hao An, Wenbin Wu

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 28, 2025

The in situ-generated pyrrolin-3-ones serve as novel and versatile synthons, being employed intermediates for the efficient production of pyrrole-fused lactones with high yield excellent enantioselectivity. Herein, we introduce emerging rhodium oxidative N-heterocyclic carbene relay catalysis that enables a highly enantioselective cascade annulation between easily available 1,2,3-triazoles enals. In this proof-of-concept study, engage α,β-unsaturated acylazolium generated from enals via catalysis.

Language: Английский

Citations

1
Highly Efficient One-Pot Synthesis of 2,4,5-Trisubstituted 3(2H)-Furanones Utilizing a Au(I)-Catalyzed Oxidation/Pinacol Rearrangement/anti-Michael Cascade DOI

Yanbin Wu,

Shuang Zang,

Hang Ren

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(36), P. 7656 - 7660

Published: Sept. 3, 2024

A highly efficient Au(I)-catalyzed cascade reaction between bispropargylic alcohols and pyridine-

Language: Английский

Citations

0