Synthesis of succinyldiamides containing all-quaternary carbon center by photo-induced amidation/smiles rearrangement of alkenes DOI
Yuyu Dai, Wei Niu, Jiapeng Huang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

A novel, mild, and environmentally friendly method was developed for the synthesis of quaternary-carbon-containing succinyldiamides. This found to be compatible with many substrates.

Language: Английский

Enantioselective Synthesis of Hydrindanes via Palladium-Catalyzed Asymmetric Desymmetrization of Cyclohexadiene Derivatives DOI

Shu Sen Wu,

Miaomiao Li,

Jiajun Lu

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

We herein disclose a strategy for the asymmetric desymmetrization of cyclohexadiene derivatives via palladium-catalyzed Heck and tandem Heck/Tsuji-Trost allylic alkoxylation reaction. By employing DCE as solvent, we obtained variety chiral hydrindanes containing an all-carbon quaternary carbon center tertiary in good yields with excellent enantioselectivities. With alcohols valuable one stereocenter two centers were constructed high level enantioinduction.

Language: Английский

Citations

0
Catalytic construction of P-stereogenic center via phosphorus-centered nucleophilic substitution DOI
Bingbing Dong, Junmin Zhang, Xiang-Yu Ye

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 111052 - 111052

Published: March 1, 2025

Language: Английский

Citations

0
Organocatalytic Enantioselective Arylation to Access Densely Aryl-Substituted P-Stereogenic Centers DOI
Huilin Hu,

Siqiang Fang,

Xingjie Luo

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

Although methods for synthesizing chiral phosphorus scaffolds are available, the potential of this molecular chirality remains largely unexplored. Herein, we present a remote desymmetrization prochiral biaryl phosphine oxides through an organocatalytic asymmetric arylation. This metal-free approach enables efficient synthesis wide range densely functionalized P(V)-stereogenic compounds with good to excellent yields and satisfactory enantioselectivities. Mechanistic studies reveal that hydrogen bonding ion-pairing interactions crucial achieving precise stereocontrol in transformation.

Language: Английский

Citations

2
A Catalytic Enantioselective Suzuki Coupling for the Modular Construction of Axially Chiral BODIPYs with Bright Solid-State Emission DOI
Jingjing Cao, Jinping Zhang, Fan Zhang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

The development of chiral BODIPYs attracts remarkable interest due to their unique properties, structural diversity, and good photochemical stability, whereas achieving the construction maintains scarce. Herein, we present an enantioselective synthesis axially through Suzuki-Miyaura coupling. newly synthesized coassembly showed desirable photophysical including high fluorescence quantum yields intense CPL, both in solution solid state.

Language: Английский

Citations

2
Synthesis of succinyldiamides containing all-quaternary carbon center by photo-induced amidation/smiles rearrangement of alkenes DOI
Yuyu Dai, Wei Niu, Jiapeng Huang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

A novel, mild, and environmentally friendly method was developed for the synthesis of quaternary-carbon-containing succinyldiamides. This found to be compatible with many substrates.

Language: Английский

Citations

0