Scandium Triflate Catalyzed Cycloadditions of Vinyl Diazo Compounds and In Situ Formed Naphthoquinone Methides

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Vinyl diazo carbonyl compounds have received great attention and are widely employed in the cycloadditions of situ formed reactive intermediates. Metal carbenes predominantly involved cycloadditions, transformations vinyl that do not proceed via metal carbene pathway been seldom reported. Herein, scandium-catalyzed 2-naphthoquinone-8-methides achieved, naphthalene-fused polycyclic products were obtained up to 88% yield. In transformation, nucleophilic conjugate addition generates diazonium intermediates, which undergo an intramolecular Friedel-Crafts reaction transesterification yield final product.

Language: Английский

Recent Advances in Catalytic Asymmetric Transformations of Bicyclobutane: A Versatile Building Block for Enantiopure Bioisosteric Molecules

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 8078 - 8093

Published: April 30, 2025

Language: Английский

Catalyst-Controlled Divergent Synthesis of Bicyclo[2.1.1]hexanes and Cyclobutenes: The Unique Effect of Au(I)

JACS Au, Journal Year: 2025, Volume and Issue: unknown

Published: May 22, 2025

Language: Английский