Cobaltaelectro-Catalyzed Oxidative C–H/N–H Activation with 1,3-Diynes by Electro-Removable Hydrazides DOI
Ruhuai Mei, Wenbo Ma,

Yin Zhang

et al.

Organic Letters, Journal Year: 2019, Volume and Issue: 21(16), P. 6534 - 6538

Published: July 31, 2019

An efficient electro-oxidative C–H/N–H activation with 1,3-diynes has been achieved a robust earth-abundant cobalt catalyst. The electrochemical C–H functionalization was accomplished ample scope and remarkable functional group compatibility in simple undivided cell. This protocol avoids the utilization of stoichiometric cost-intensive chemical oxidants activation, thus forming hydrogen as only byproduct.

Language: Английский

Cupraelectro-Catalyzed Alkyne Annulation: Evidence for Distinct C–H Alkynylation and Decarboxylative C–H/C–C Manifolds DOI
Cong Tian, Uttam Dhawa, Alexej Scheremetjew

et al.

ACS Catalysis, Journal Year: 2019, Volume and Issue: 9(9), P. 7690 - 7696

Published: July 12, 2019

Synthetically meaningful isoindolones were accessed by cupraelectro-catalyzed C–H activation with electricity as terminal oxidant. Thus, a versatile, inexpensive, and nontoxic Cu(OAc)2 catalyst enabled broadly applicable C–H/N–H functionalizations on electron-rich electron-deficient benzamides distinct functional group tolerance resource-economy. Detailed mechanistic studies provided strong support for alkynylation mechanism through fast metalation, which likewise set the stage C–H/C–C in decarboxylative fashion.

Language: Английский

Citations

88
Cobaltaelectro‐Catalyzed C−H Activation with Carbon Monoxide or Isocyanides DOI
Samaresh Sau, Ruhuai Mei, Julia Struwe

et al.

ChemSusChem, Journal Year: 2019, Volume and Issue: 12(13), P. 3023 - 3027

Published: March 21, 2019

Abstract Electrochemical oxidative C−H/N−H activations with isocyanides have been realized a versatile cobalt catalyst. The widely applicable catalysis manifold further enabled electrooxidative carbonylations carbon monoxide under ambient conditions. C−H functionalizations were efficiently ample scope and outstanding functional group tolerance in user‐friendly undivided cell setup.

Language: Английский

Citations

84
Intermolecular Anodic Oxidative Cross-Dehydrogenative C(sp3)–N Bond-Coupling Reactions of Xanthenes with Azoles DOI

Yong‐Zheng Yang,

Ren‐Jie Song,

Jin‐Heng Li

et al.

Organic Letters, Journal Year: 2019, Volume and Issue: 21(9), P. 3228 - 3231

Published: April 18, 2019

A new anode strategy for accessing xanthen-9-azoles via an electrochemical C(sp3)-H/N-H cross-coupling of xanthenes with azoles is described. This reaction proceeds efficiently a broad scope both and N-H-free under metal- additional oxidant-free conditions represents access to direct incorporation important N-heterocycle units into the resulting xanthenes.

Language: Английский

Citations

84
Renewable resources for sustainable metallaelectro-catalysed C–H activation DOI Creative Commons
Ramesh C. Samanta, Tjark H. Meyer, Inke Siewert

et al.

Chemical Science, Journal Year: 2020, Volume and Issue: 11(33), P. 8657 - 8670

Published: Jan. 1, 2020

The merger of C–H activation with electrosynthesis, powered by renewable energies and resources, will guide towards a sustainable future.

Language: Английский

Citations

84
Cobaltaelectro-Catalyzed Oxidative C–H/N–H Activation with 1,3-Diynes by Electro-Removable Hydrazides DOI
Ruhuai Mei, Wenbo Ma,

Yin Zhang

et al.

Organic Letters, Journal Year: 2019, Volume and Issue: 21(16), P. 6534 - 6538

Published: July 31, 2019

An efficient electro-oxidative C–H/N–H activation with 1,3-diynes has been achieved a robust earth-abundant cobalt catalyst. The electrochemical C–H functionalization was accomplished ample scope and remarkable functional group compatibility in simple undivided cell. This protocol avoids the utilization of stoichiometric cost-intensive chemical oxidants activation, thus forming hydrogen as only byproduct.

Language: Английский

Citations

83