Recent process of using nanoparticles in the T cell-based immunometabolic therapy DOI Creative Commons

Bingxin Chen,

Yang Yang Li, Hui Wang

et al.

Nanotechnology Reviews, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Immunotherapy is currently the main treatment for malignant tumors by activating immune cell. Metabolic reprogramming in tumor microenvironment can greatly affect function of cell, and T cell anti-tumor effector Therefore, cell-based immunometabolic therapy improve clinical efficacy. In therapy, regular agents conventional forms are difficult to achieve intended efficacy due poor permeability low cellular uptake. Nanoparticle-based strategy serve as optimal targeted drug delivery system co-encapsulation multiple therapeutic stable loading. Here, we intend summarize examples nanoparticles provide a comprehensive helpful review covering notable vital applications nanotechnology-based strategies therapy.

Language: Английский

Recent process of using nanoparticles in the T cell-based immunometabolic therapy DOI Creative Commons

Bingxin Chen,

Yang Yang Li, Hui Wang

et al.

Nanotechnology Reviews, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Immunotherapy is currently the main treatment for malignant tumors by activating immune cell. Metabolic reprogramming in tumor microenvironment can greatly affect function of cell, and T cell anti-tumor effector Therefore, cell-based immunometabolic therapy improve clinical efficacy. In therapy, regular agents conventional forms are difficult to achieve intended efficacy due poor permeability low cellular uptake. Nanoparticle-based strategy serve as optimal targeted drug delivery system co-encapsulation multiple therapeutic stable loading. Here, we intend summarize examples nanoparticles provide a comprehensive helpful review covering notable vital applications nanotechnology-based strategies therapy.

Language: Английский

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