Kobunshi, Journal Year: 2024, Volume and Issue: 73(11), P. 567 - 570
Published: Jan. 1, 2024
Language: Английский
Device, Journal Year: 2024, Volume and Issue: 2(10), P. 100499 - 100499
Published: Aug. 7, 2024
Fast, affordable, and reliable access to complex glycans is essential meet the demand for custom-made research tools glycosciences. Automated glycan assembly (AGA), based on solid-phase synthesis paradigm allows quickly producing a range of biologically relevant oligosaccharides. The instrument sets limits as types chemistries that can be executed. new, smaller, more economical device quick temperature adjustments between −40°C +90°C an energy-efficient local-temperature-controlled (LTC) reactor. power new illustrated in context several AGA syntheses
Language: Английский
Citations
4
Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 336, P. 103361 - 103361
Published: Nov. 29, 2024
Language: Английский
Citations
3
Nature Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 26, 2025
Language: Английский
Citations
0
Nachrichten aus der Chemie, Journal Year: 2025, Volume and Issue: 73(3), P. 40 - 70
Published: Feb. 28, 2025
Abstract Highlights von November 2023 bis 2024: die erste Einelektron‐C–C‐σ‐Bindung und Anti‐Bredt‐Verbindung; gesättigte Heterocyclen elektrochemisch funktionalisieren; Ausrichten diskotischer Flüssigkristalle; enantioselektive Wagner‐Meerwein‐Umlagerung reiner Aliphaten; photokatalytisch Furanen zu Pyrrolen; mit Ammoniak primären Arylaminen; Metallschrott recyceln ionischen Flüssigkeiten; terminale Alkene Ni‐Katalysatoren zum (Z)‐ oder (E)‐Alken isomerisieren;neue Fungizide, Medikamente Alkaloide.
Citations
0
Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown
Published: April 24, 2025
Glycans are intrinsically flexible molecules that can adopt many conformations. These often carry ionic functional groups influence glycan's conformational preferences, dynamics, and aggregation tendencies. Inspired by these mechanisms, we have engineered a glycan sequence whose secondary structure be precisely manipulated using groups. We strategically incorporated substituents into adopting hairpin conformation. Complementary stabilized the closed conformers, while repulsions shifted populations toward open forms. External stimuli, such as pH variations or enzyme addition, enabled us to dynamically control hairpin's opening closing. Additionally, changes in protonation states led aggregation, suggesting opportunities for creation of responsive glycan-based materials.
Language: Английский
Citations
0
Organic Letters, Journal Year: 2024, Volume and Issue: 26(10), P. 2034 - 2038
Published: March 4, 2024
Tuberculosis (TB) is one of the most dreadful diseases, killing more than 3 million humans annually. M. tuberculosis (MTb) causative agent for TB and has a thick waxy cell wall, making it an attractive target immunological studies. In this study, heptamannopyranoside containing 1 → 2 6 α-mannopyranosidic linkages been explored evaluations. The conjugation-ready was synthesized by exploiting salient features recently discovered [Au]/[Ag]-glycosidation ethynylcyclohexyl glycosyl carbonate donors. glycan conjugated to ESAT6, early secreted protein MTb further characterization as potential subunit vaccine candidate.
Language: Английский
Citations
2
Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(35), P. 7133 - 7137
Published: Jan. 1, 2024
An on resin approach for the synthesis of phosphoethanoamine (pEtN) cellulose, a chemically modified cellulose present in some bacterial biofilms.
Language: Английский
Citations
1
Kobunshi, Journal Year: 2024, Volume and Issue: 73(11), P. 567 - 570
Published: Jan. 1, 2024
Language: Английский
Citations
0