Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: May 29, 2025
Simultaneous construction of two new C-C bonds in the alkene substrates regioselectively is significantly challenging. Herein, we report an unprecedented regioselective arylcarboxylation strategy activated alkenes with readily available aryl halides and tetrabutylammonium oxalate as reductant C1 source under visible-light-induced conditions. The reaction proceeds smoothly to access various carboxylic acids absence any catalysts, additives, metal promoters, or pre-established CO2 atmosphere. electron donor-acceptor (EDA) complex formed between stoichiometric amounts trigger single-electron reduction relay process after irradiation visible light. situ generated oxalic radical anion species undergoes homolysis bond releases potent source, respectively, facilitate reductive carboxylation.
Language: Английский