Biosensors,
Journal Year:
2023,
Volume and Issue:
13(8), P. 823 - 823
Published: Aug. 15, 2023
Hydrogel-based
wearable
electrochemical
biosensors
(HWEBs)
are
emerging
biomedical
devices
that
have
recently
received
immense
interest.
The
exceptional
properties
of
HWEBs
include
excellent
biocompatibility
with
hydrophilic
nature,
high
porosity,
tailorable
permeability,
the
capability
reliable
and
accurate
detection
disease
biomarkers,
suitable
device–human
interface,
facile
adjustability,
stimuli
responsive
to
nanofiller
materials.
Although
biomimetic
three-dimensional
hydrogels
can
immobilize
bioreceptors,
such
as
enzymes
aptamers,
without
any
loss
in
their
activities.
However,
most
suffer
from
low
mechanical
strength
electrical
conductivity.
Many
studies
been
performed
on
electroactive
nanofillers,
including
biomacromolecules,
carbon-based
materials,
inorganic
organic
nanomaterials,
tackle
these
issues.
Non-conductive
even
conductive
may
be
modified
by
well
redox
species.
All
modifications
led
design
development
efficient
nanocomposites
biosensors.
In
this
review,
both
conductive-based
non-conductive-based
derived
natural
synthetic
polymers
systematically
reviewed.
main
synthesis
methods
characterization
techniques
addressed.
behavior
discussed
detail.
Finally,
prospects
potential
applications
biosensing,
healthcare
monitoring,
clinical
diagnostics
highlighted.
Advanced Materials Technologies,
Journal Year:
2023,
Volume and Issue:
8(15)
Published: May 19, 2023
Abstract
Recent
progress
in
flexible
sensors
and
piezoelectric
materials
has
enabled
the
development
of
continuous
monitoring
systems
for
human
physiological
signals
as
wearable
implantable
medical
devices.
However,
their
non‐degradable
characteristics
also
lead
to
generation
a
significant
amount
non‐decomposable
electronic
waste
(e‐waste)
necessitate
secondary
surgery
implant
removal.
Herein,
biodegradable
material
devices
that
addresses
problem
e‐waste
while
providing
high‐performance
platform
seamless
tactile
stimuli
is
provided.
The
novel
composition
bioresorbable
poly(
l
‐lactide)
glycine
leads
non‐invasive
measurement
artery
pulse
near‐surface
arteries
slight
movement
muscle,
including
trachea,
esophagus,
movements
joints.
complete
degradability
film
phosphate‐buffered
saline
at
37
°C
shown.
developed
pressure
sensor
exhibits
high
sensitivity
13.2
mV
kPa
−1
with
response
time
10
ms
shows
good
mechanical
stability.
This
comparable
performance
commonly
used
measuring
signals.
It
can
be
temporary
due
its
degradable
nature.
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(8), P. 823 - 823
Published: Aug. 15, 2023
Hydrogel-based
wearable
electrochemical
biosensors
(HWEBs)
are
emerging
biomedical
devices
that
have
recently
received
immense
interest.
The
exceptional
properties
of
HWEBs
include
excellent
biocompatibility
with
hydrophilic
nature,
high
porosity,
tailorable
permeability,
the
capability
reliable
and
accurate
detection
disease
biomarkers,
suitable
device–human
interface,
facile
adjustability,
stimuli
responsive
to
nanofiller
materials.
Although
biomimetic
three-dimensional
hydrogels
can
immobilize
bioreceptors,
such
as
enzymes
aptamers,
without
any
loss
in
their
activities.
However,
most
suffer
from
low
mechanical
strength
electrical
conductivity.
Many
studies
been
performed
on
electroactive
nanofillers,
including
biomacromolecules,
carbon-based
materials,
inorganic
organic
nanomaterials,
tackle
these
issues.
Non-conductive
even
conductive
may
be
modified
by
well
redox
species.
All
modifications
led
design
development
efficient
nanocomposites
biosensors.
In
this
review,
both
conductive-based
non-conductive-based
derived
natural
synthetic
polymers
systematically
reviewed.
main
synthesis
methods
characterization
techniques
addressed.
behavior
discussed
detail.
Finally,
prospects
potential
applications
biosensing,
healthcare
monitoring,
clinical
diagnostics
highlighted.
