Optimizing Electrospun PVA Fibers with MXene Integration for Biomedical Applications DOI Creative Commons
Nergis Zeynep Renkler, Zaheer Ud Din Babar, Mario Barra

et al.

Macromolecular Materials and Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Abstract MXene‐based materials have gained attention in the biomedical field due to their promising biocompatibility, improved mechanical strength, and conductivity. In this study, focus is on optimizing MXene‐incorporated electrospun fibers subsequent characterizations assess potential for applications. Polyvinyl alcohol (PVA) used as appropriate matrix material process parameters are finetuned ensure effective incorporation of MXene. XRD spectroscopic analysis confirm successful synthesis integration MXenes into nanofibers. Morphological shows that MXene led formation sub‐micrometer with smooth surfaces reduced fiber diameter (587 ± 191 nm) compared pure PVA (696 ±160 nm). Investigations electrical characteristics demonstrate a fourfold increase conductivity nanofibers (σ = 1.90 0.45 × 10 −8 S cm −1 ) after addition (compared σ 0.46 0.05 PVA‐only fibers). Furthermore, MXene‐PVA system demonstrates nearly twofold stiffness, E 136.87 19.63 MPa than 71.42 16.56 PVA. Moreover, initial vitro experiments indicate L929 cell viability. These findings position composites highly versatile platform advanced devices, such electroactive tissue scaffolds wearable sensors.

Language: Английский

Advances in conducting nanocomposite hydrogels for wearable biomonitoring DOI
Arpita Roy, Ronak Afshari, Saumya Jain

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Recent advancements in wearable biosensors and bioelectronics highlight biocompatible conducting nanocomposite hydrogels as key components for personalized health devices soft electronics.

Language: Английский

Citations

0
MoS2 Nanozyme–Chlorella Hydrogels: Pioneering a Hepatocellular Carcinoma Integrative Therapy DOI Open Access
Mengya Zhang, Jingsheng Zhou,

Xianghe Jiang

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 9, 2025

Abstract Hepatocellular carcinoma (HCC) poses a formidable challenge to global health, and surgical resection is the predominant therapeutic strategy. However, efficacy of postoperative adjuvant treatments often compromised by need preserve liver function. The authors’ meta‐analysis reveals significant correlation between impaired function decreased survival rates in HCC patients, highlighting critical for interventions protect To address this, an innovative injectable composite hydrogel system engineered, designated MC@PHDA, which encapsulates Molybdenum disulfide MoS 2 nanozymes Chlorella photosensitizers within hyaluronic acid‐dopamine/2‐aminoethyl methacrylate (HA‐DA/AMA) matrix. This offers comprehensive approach HCC, combining photodynamic photothermal therapies selectively target eradicate cancer cells; while, inducing immunogenic cell death (ICD) stimulate antitumor immune response. MC@PHDA leverages ROS‐scavenging properties mitigate oxidative injury promote hepatocyte regeneration. Thus, multifaceted design represents paradigm‐shifting strategy treatment that targets tumor concurrently promoting repair study introduces groundbreaking integrative management with potential significantly enhance patient quality life.

Language: Английский

Citations

0
Development and characterization of nano-hydroxyapatite/gelatin/PVA/alginate-based multifunctional active scaffolds for bone regeneration: An in vitro and in vivo study DOI
Nadia R El-Bahrawy, Ahmed Hafez, Ahmed Elmekawy

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141160 - 141160

Published: Feb. 1, 2025

Language: Английский

Citations

0
Fertile Ground for Homeostatic Reformation: Engineered Release Platforms for Enhanced Regenerative Outcomes DOI
Pei Wang, Yan Gong,

Xiansong Wang

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: 106, P. 106740 - 106740

Published: Feb. 21, 2025

Language: Английский

Citations

0
Optimizing Electrospun PVA Fibers with MXene Integration for Biomedical Applications DOI Creative Commons
Nergis Zeynep Renkler, Zaheer Ud Din Babar, Mario Barra

et al.

Macromolecular Materials and Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Abstract MXene‐based materials have gained attention in the biomedical field due to their promising biocompatibility, improved mechanical strength, and conductivity. In this study, focus is on optimizing MXene‐incorporated electrospun fibers subsequent characterizations assess potential for applications. Polyvinyl alcohol (PVA) used as appropriate matrix material process parameters are finetuned ensure effective incorporation of MXene. XRD spectroscopic analysis confirm successful synthesis integration MXenes into nanofibers. Morphological shows that MXene led formation sub‐micrometer with smooth surfaces reduced fiber diameter (587 ± 191 nm) compared pure PVA (696 ±160 nm). Investigations electrical characteristics demonstrate a fourfold increase conductivity nanofibers (σ = 1.90 0.45 × 10 −8 S cm −1 ) after addition (compared σ 0.46 0.05 PVA‐only fibers). Furthermore, MXene‐PVA system demonstrates nearly twofold stiffness, E 136.87 19.63 MPa than 71.42 16.56 PVA. Moreover, initial vitro experiments indicate L929 cell viability. These findings position composites highly versatile platform advanced devices, such electroactive tissue scaffolds wearable sensors.

Language: Английский

Citations

0