Over
the
years,
oral
and
maxillofacial
injuries,
mainly
caries,
pulpitis,
bone
defects,
cancer,
often
involve
a
variety
of
organs
tissues,
resulting
in
structural
dysfunction,
adverse
effects
on
facial
appearance,
not
only
affecting
people's
chewing,
swallowing
other
physiological
functions,
but
also
to
physical
mental
health
burden.
As
type
carbon-based
nanomaterial,
carbon
dots
(CDs)
have
been
widely
used
diagnosis
treatment
diseases
due
its
excellent
optical
properties,
good
biocompatibility
low
toxicity.
In
addition,
surface
functionalization
or
passivation
CDs
can
change
properties
CDs,
such
as
water
solubility
chemiluminescence,
broaden
biomedical
potential
CDs.
this
review,
latest
research
progress
modified
hard
tissue
regeneration,
tumor
treatment,
antibacterial
activity,
dentin
pulp
complex
teeth
whitening,
wound
healing,
drug
release,
fluorescence
tracer
bioimaging
were
reviewed.
we
discussed
problems
future
direction
development.
Achieving
antitumor
immunotherapy
based
on
hybridization
of
multiple
types
inactivated
cells
has
attracted
a
lot
attention.
However,
the
hybridized
disordered
structure
could
result
in
shedding
antigens
and
their
transfer
to
immune
cells,
which
suppresses
tumor
immunity
through
trogocytosis.
Here,
we
report
strategy
for
situ
solidification
whole
cell
by
biomineralization
sustained
stimulation
immunity.
The
near-infrared
light
was
used
accelerate
breaking
Au=P
bonds
auranofin,
exposed
Au
atoms
biomineralize
at
secondary
(β-corner)
protein
form
nanocrystals
with
coronas
cells.
are
anchored
coronas,
fixes
morphology
rendering
them
physiologically
inactive.
Interestingly,
this
solidified
prevents
from
undergoing
trogocytosis,
inhibits
proximal
distal
growth.
Thus,
study
presents
its
potential
application
immunotherapy.
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 13, 2025
Abstract
Carbon
quantum
dots
(CQDs)
with
photoluminescence
properties
have
been
widely
recognized,
however,
their
inherent
surface-enhanced
Raman
scattering
(SERS)
activity
is
rare
reported.
Herein,
we
propose
a
type
of
band-gap-tunable
CQDs
derived
from
metal-phenolic
network
(MPN)
that
exhibits
excellent
SERS
performance.
MPN-CQDs
may
be
the
ideal
nonmetallic
substrates
to
accurately
elucidate
chemical
mechanism
(CM)
due
simply
controllable
bandgap
structure.
By
screening
doped
metal
elements
MPN,
can
realize
optimal
effect
maximum
enhancement
factor
5.5×104,
also
exhibit
outstanding
reproducibility
and
stability.
We
then
systematically
disclose
interfacial
photo-induced
charge
transfer
process
corresponding
migration
pathways
between
analyte.
This
class
finally
applied
for
detection
hemoglobin
high
sensitivity;
further
combined
machine
learning
algorithm,
successfully
achieved
precise
identification
heterogeneity
hemoglobin.
first
evidence
tunable
performance
in
CQDs,
which
offers
facile
avenue
in-depth
understanding
CM
materials.
Exploration,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 6, 2025
ABSTRACT
Inorganic
protein
hybrid
materials
(IPHMs)
due
to
editable
structure
present
unrivalled
potential
at
the
intersection
of
synthetic
biology
and
science.
The
synthesis
IPHMs
with
a
high
degree
biosafety
from
bioactive
units
represents
shift
in
material
design
synthesis.
This
paper
focuses
on
review
structural
basis
principles
proteins
for
specific
physical
chemical
functions.
It
also
provides
valuable
reference
emerging
through
conformational
relationship
IPHMs,
which
extends
applications
IPHMs.
In
addition,
construction
strategy
reaction
system
is
analyzed
perspective
biology.
possibility
engineering
batch
discussed.
Based
physicochemical
properties
different
applied‐oriented
research
biomedical
optical
imaging
multimodal
therapy,
idea
situ
proposed.
Ultimately,
trends
challenges
are
speculated
detail.
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(3), P. 110 - 110
Published: March 20, 2025
We
are
committed
to
writing
this
narrative
review
given
that
carbon-based
nanomaterials
revolutionizing
dental
medicine.
Since
the
groundbreaking
discovery
of
carbon
nanotubes
in
1991,
their
applications
have
skyrocketed.
The
numbers
speak
for
themselves:
2024,
global
market
hit
USD
1.3
billion
and
is
set
double
2.6
by
2029.
Over
past
few
decades,
various
forms
been
integrated
into
practices,
elevating
quality
effectiveness
treatments.
They
represent
a
transformative
advancement
dentistry,
offering
numerous
benefits
such
as
augmented
mechanical
properties,
antimicrobial
activity,
potential
regenerative
applications.
Both
(CNTs)
dots
(CDs)
derived
from
integral
nanotechnology,
showcasing
versatility
nanostructures
delivering
cutting-edge
solutions
across
diverse
domains,
electronics,
materials
science,
biomedicine.
CNTs
ambitiously
examined
capability
reinforce
materials,
develop
biosensors
detecting
oral
diseases,
even
deliver
therapeutic
agents
directly
affected
tissues.
This
synthesizes
current
applications,
underscores
interdisciplinary
value
bridging
nanotechnology
identifies
key
barriers
clinical
adoption,
discusses
hybrid
strategies
warranting
further
research
advance
implementation.
Inorganic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 8, 2025
Organic
room-temperature
phosphorescence
(RTP)
materials
are
widely
used
in
optoelectronics,
biological
imaging,
and
chemical
sensing
because
of
their
long
luminous
lifetime
excellent
signal-to-noise
ratio.
Although
multicolor
RTP
systems
show
important
potential
for
information
encryption,
spin-orbit
coupling
(SOC)
weakening
exciton
quenching
caused
by
molecular
motion
environmental
factors
limit
stable
triplet
generation,
thereby
reducing
the
quantum
yield
brightness
materials.
In
this
study,
we
developed
a
novel
carbon
dot
(CD)
to
effectively
solve
these
problems
using
multiconfinement
system,
demonstrating
excitation-dependent
properties.
The
synthesized
CDs
varies
from
green
orange
under
different
excitation
wavelengths,
with
high
photoluminescent
(54.22%)
(39.53
cd/m2).
Through
detailed
experimental
theoretical
studies,
found
that
photoluminescence
phenomena
arise
existence
multiple
luminescence
centers,
which
form
complex
network
structures
through
hydrogen,
covalent,
ionic
bonds,
thus
stabilizing
excitons
enhancing
optical
addition,
synthetic
material
shows
application
field
encryption
anticounterfeiting,
achieving
dynamic
light
display
functions,
improving
security
anticounterfeiting
capabilities.
ACS Materials Letters,
Journal Year:
2024,
Volume and Issue:
6(9), P. 4302 - 4311
Published: Aug. 20, 2024
Sonosensitization-mediated
reactive
oxygen
species
generation
associated
with
energy
and
electron
transfer
is
an
essential
process
of
sonodynamic
therapy.
However,
the
development
sonosensitizers
both
high
intersystem
crossing
(ISC)
rates
efficient
carrier
separation
remains
greatly
challenging.
Herein,
we
present
a
new
scheme
to
construct
class
heterojunctions
(MC-R,
R
=
−H,
−OCH3,
−Br)
by
Zr-based
metal–organic
framework
(NU-901)
porphyrin-based
covalent
organic
polymers
(COPs)
different
substituents.
In
this
sonocatalytic
system,
type-II
heterojunction
based
on
NU-901
COPs
can
effectively
promote
electron–hole
pairs,
increasing
superoxide
anions,
while
introduction
substituents
(−OCH3,
extend
conjugation
p-π
binding
enhance
spin–orbit
coupling
through
heavy
atom
effects,
which
could
regulate
ISC
improve
quantum
yield
singlet
oxygen.
Remarkably,
MC-Br
as
representative
MC-R
exhibits
best
tumor
inhibition
efficiency
in
vivo.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 23, 2024
Abstract
Carbon
dots
(CDs)
with
intrinsic
bioactivities
are
candidates
for
bioimaging
and
disease
therapy
due
to
their
diverse
bioactivities,
high
biocompatibility,
multiple
functionalities
in
multimodal
theranostics.
It
is
a
multidisciplinary
research
hotspot
that
includes
biology,
physics,
materials
science,
chemistry.
This
progress
report
discusses
the
CDs
applications
The
relationship
between
synthesis
structure
of
summarized
analyzed
from
material
chemical
perspective.
including
anti‐tumor,
antibacterial,
anti‐inflammatory
etc.
discussed
biological
points
view.
Subsequently,
optical
electronic
properties
can
be
applied
biomedical
field
physical
Based
on
functional
review
CDs,
reviewed,
diagnosis
treatment,
activity,
Unlike
previous
reviews,
this
combines
disciplines
gain
more
comprehensive
understanding
mechanisms,
functions,
bioactivities.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 10899 - 10915
Published: Oct. 1, 2024
Recent
advances
in
tumor
immunotherapy
have
highlighted
the
pivotal
role
of
carbon
nanomaterials,
such
as
dots,
graphene
quantum
and
nanotubes.
This
review
examines
unique
benefits
these
materials
cancer
treatment,
focusing
on
their
mechanisms
action
within
immunotherapy.
These
include
applications
immunoregulation,
recognition,
enhancement.
We
explore
how
nanomaterials
when
combined
with
specific
biomolecules,
can
form
immunosensors.
sensors
are
engineered
for
highly
sensitive
detection
markers,
offering
crucial
support
early
diagnosis
timely
therapeutic
interventions.
also
addresses
significant
challenges
facing
clinical
settings,
issues
related
to
long-term
biocompatibility
hurdles
translation.
require
extensive
ongoing
research
discussion.
is
both
theoretical
practical
importance,
aiming
promote
using
immunotherapy,
potentially
transforming
outcomes
enhancing
patient
care.
