Critical Reviews in Food Science and Nutrition,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 19
Published: Dec. 30, 2024
Multi-target
detection
technology
in
food
plays
a
key
role
the
field
of
analysis,
which
can
comprehensively
and
accurately
assess
levels
multiple
residues
food,
thus
ensuring
safety
quality.
In
recent
years,
smart
nanostructured
molecular
logic
technologies
(SNMLT)
have
been
widely
employed
multiplex
detection.
Of
these,
component
materials-based
SNMLT
attracted
much
attention
owing
to
their
rapid
response,
multifunctionality,
programmability,
high
sensitivity.
Nevertheless,
there
is
no
review
focusing
on
sensing
platform
for
multi-target
current
review,
principles
operation
classification
were
first
described,
followed
by
summary
materials
signal
output
strategies
SNMLT.
Besides,
applications
assay,
including
physical,
biological,
chemical
hazard
factors
quality
also
highlighted.
Finally,
future
challenges
summarized
discussed.
The
indicates
that
has
advantages
wide
range,
strong
anti-interference
ability,
ability
analyze
target
analytes
simultaneously
research
focus
combining
with
artificial
intelligence
develop
inexpensive
easy-to-use
devices.
Journal of Materials Chemistry B,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
DNA
computing
is
a
key
molecular
method
in
biological
analysis.
This
review
highlights
advancements
logic
systems,
material
innovations,
and
applications
imaging,
diagnosis,
treatment,
addressing
challenges
future
directions.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(76), P. 10536 - 10539
Published: Jan. 1, 2024
DNA
circuits
are
important
fundamental
tools
for
performing
temporal
logic
operations
with
complex
structures,
but
they
lack
sequence
orthogonality.
Here,
we
developed
a
simple
and
orthogonal
hairpin
exonuclease
assistance
signal
(H-EAST)
architecture
to
construct
domino
time-delay
characteristics
operations,
which
has
potential
applications
in
biomolecular
computing.
New Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
48(42), P. 18320 - 18328
Published: Jan. 1, 2024
Based
on
the
enzyme-resistant
properties
of
G-quadruplexes,
combined
with
Exo
III
and
λ
,
a
G-quadruplex-regulated
exonuclease
cooperative
hydrolysis
signal
transduction
strategy
is
proposed
applied
to
processing
molecular
temporal
information.
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(42), P. 16735 - 16742
Published: Oct. 14, 2024
A
key
challenge
for
achieving
high-efficient
DNA
strand
displacement
reaction
(SDR)
with
existing
technologies
is
the
inferior
kinetic
performance
due
to
alternately
cumbersome
conjunction
and
dissociation
of
dsDNA.
In
this
work,
a
novel
multidriven
SDR
collaborated
by
toehold
initiator,
towing,
click
chemistry
engineered.
The
invasion
(O)
endows
hybridization
basal
(M)
in
dsDNA
releasing
(P),
which
can
be
significantly
boosted
towing
helper
impetus
from
reaction.
Accordingly,
rate
extent
P
largely
improved
showed
desiring
close
6-fold
compared
traditional
method,
providing
newly
strategy
potential
application
biosensing,
clinical
diagnostics,
nanotechnology.
view
this,
practical
biosensing
platform
combining
(MSDR)
waste-free
multi-cycle
amplification
constructed
rapid
ultrasensitive
electrochemical
detection
cancer-related
miRNA-21.
substantial
output
as
an
target-triggered
multicycle
high-efficiently
release
signal
probe
(Fc)-labeled
(P)
on
electrode
using
proposed
MSDR,
obtaining
low
limit
below
106.8
aM.
Nanoscale,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
The
discovery
for
the
first
time
that
phosphorothioate
modifications
can
enhance
rate
of
TMSD
in
short
toehold
region.
Furthermore,
we
applied
our
findings
to
CHA
circuits
and
DNA
probabilistic
circuits.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 19
Published: Dec. 30, 2024
Multi-target
detection
technology
in
food
plays
a
key
role
the
field
of
analysis,
which
can
comprehensively
and
accurately
assess
levels
multiple
residues
food,
thus
ensuring
safety
quality.
In
recent
years,
smart
nanostructured
molecular
logic
technologies
(SNMLT)
have
been
widely
employed
multiplex
detection.
Of
these,
component
materials-based
SNMLT
attracted
much
attention
owing
to
their
rapid
response,
multifunctionality,
programmability,
high
sensitivity.
Nevertheless,
there
is
no
review
focusing
on
sensing
platform
for
multi-target
current
review,
principles
operation
classification
were
first
described,
followed
by
summary
materials
signal
output
strategies
SNMLT.
Besides,
applications
assay,
including
physical,
biological,
chemical
hazard
factors
quality
also
highlighted.
Finally,
future
challenges
summarized
discussed.
The
indicates
that
has
advantages
wide
range,
strong
anti-interference
ability,
ability
analyze
target
analytes
simultaneously
research
focus
combining
with
artificial
intelligence
develop
inexpensive
easy-to-use
devices.
