Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: April 6, 2025
Abstract
Lignin,
the
most
abundant
natural
aromatic
macromolecule,
holds
significant
potential
for
high-value
applications.
However,
its
complex
and
irregular
structure,
along
with
challenges
in
efficient
processing,
has
limited
widespread
use.
In
this
study,
we
propose
an
ecofriendly
continuous
process
utilizing
deep
eutectic
solvents
(DESs)
lignin
depolymerization
subsequent
production
of
nanoparticles.
DESs,
composed
choline
chloride
lactic
acid,
effectively
break
down
into
low-molecular-weight
homogeneous
fragments
while
also
serving
as
a
solvent
nanoparticle
formation.
The
depolymerized
nanoparticles
(DLNPs)
exhibited
uniform
particle
size
distribution
enhanced
surface
charge
due
to
interactions
DES,
resulting
excellent
long-term
dispersion
stability.
Chemical
analyses
indicated
that
primarily
involved
cleavage
β-O-4
linkages
retaining
structure
forming
condensation
products
such
pinoresinol
phenylcoumaran.
Thermal
analysis
revealed
DLNP
produced
through
displayed
improved
thermal
stability
compared
kraft
lignin,
suggesting
applications
high-temperature
environments,
flame
retardants.
This
study
demonstrates
DES-based
is
promising
alternative
conventional
organic
methods,
providing
sustainable
pathway
valorization.
As
the
second
most
important
fungal
pathogen,
Botrytis
cinerea
(B.
cinerea)
poses
a
serious
threat
to
crop
yields
and
agricultural
safety.
Pyraclostrobin
(PYR),
broad-spectrum
QoI
fungicide,
has
been
widely
utilized
since
its
launch
in
2003.
However,
inhibitory
effects
of
both
PYR
technical
formulations
on
B.
are
not
outstanding.
Even
at
concentration
50
μg/mL,
inhibition
rates
by
remain
below
85%.
In
this
work,
we
prepared
an
acid-responsive
Pickering
emulsion
encapsulating
(PYR@BTIB-PE),
which
completely
inhibited
low
concentrations
(25
μg/mL)
for
first
time.
The
PYR@BTIB-PE
achieved
fragmentation
release
within
4
min
pH
5,
was
consistent
with
around
cinerea.
can
rapidly
when
infected
increased
cinerea,
thereby
enhancing
efficacy
PYR.
addition,
released
organic
solvent
from
enhanced
passing
property
membrane,
facilitating
more
enter
body
improvement
membrane
rapid
response
worked
together
achieve
complete
Furthermore,
flexible
amphiphilic
structures
interaction
leaf
surface,
suppressed
droplet
splashing,
promoted
spreading,
reducing
pesticide
loss
improving
utilization
rate
pesticide.
This
study
presents
efficient
strategy
inhibiting
is
also
expected
be
extended
other
antifungal
preparations.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: April 6, 2025
Abstract
Lignin,
the
most
abundant
natural
aromatic
macromolecule,
holds
significant
potential
for
high-value
applications.
However,
its
complex
and
irregular
structure,
along
with
challenges
in
efficient
processing,
has
limited
widespread
use.
In
this
study,
we
propose
an
ecofriendly
continuous
process
utilizing
deep
eutectic
solvents
(DESs)
lignin
depolymerization
subsequent
production
of
nanoparticles.
DESs,
composed
choline
chloride
lactic
acid,
effectively
break
down
into
low-molecular-weight
homogeneous
fragments
while
also
serving
as
a
solvent
nanoparticle
formation.
The
depolymerized
nanoparticles
(DLNPs)
exhibited
uniform
particle
size
distribution
enhanced
surface
charge
due
to
interactions
DES,
resulting
excellent
long-term
dispersion
stability.
Chemical
analyses
indicated
that
primarily
involved
cleavage
β-O-4
linkages
retaining
structure
forming
condensation
products
such
pinoresinol
phenylcoumaran.
Thermal
analysis
revealed
DLNP
produced
through
displayed
improved
thermal
stability
compared
kraft
lignin,
suggesting
applications
high-temperature
environments,
flame
retardants.
This
study
demonstrates
DES-based
is
promising
alternative
conventional
organic
methods,
providing
sustainable
pathway
valorization.
