Recent nanoengineered therapeutic advancements in sepsis management DOI Creative Commons
Li Liu, Li Li, Ting Wang

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 5, 2024

Sepsis (defined as sepsis 3.0) is a life-threatening organ dysfunction caused by dysregulated host response to variety of pathogenic microorganisms. Characterized high morbidity and mortality, has become global public health problem. However, there lack appropriate diagnostic therapeutic strategies for current management rely on the limited treatment strategies. Recently, nanomedicines targeting controlling release bio-active agents have shown excellent potency in management, with improved efficacy reduced adverse effects. In this review, we summarized advantages nanomaterials. Also, preparation main categories anti-sepsis applied are described detail, including antibiotic-coated nanomaterials, antimicrobial peptides-coated biomimetic nanomaterials macrophages natural products loaded These advances establish huge potential nanomaterials-based especially pharmaceutical pharmacological properties, enhanced efficacy, controllable drug-targeting side To further facilitate clinical translation nanomedicines, propose that issues involving safety, regulatory laws cost-effectiveness should receive much more attention future.

Language: Английский

Minimizing Buried Interface Energy Losses with Post‐Assembled Chelating Molecular Bridges for High‐Performance and Stable Inverted Perovskite Solar Cells DOI Open Access
Bo Yu, Kai Wang, Yapeng Sun

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Abstract Self‐assembled monolayers (SAMs) as hole‐collecting materials have made remarkable progress in inverted perovskite solar cells (PSCs). However, the incomplete coverage of SAMs and non‐intimate interface contact between perovskite/SAMs usually cause inferior characteristics significant energy losses at heterojunction interface. Herein, a post‐assembled chelating molecular bridge strategy using 5‐(9H‐carbazol‐9‐yl)isophthalicacid (CB‐PA) is developed to modify buried It found that CB‐PA can be chemically coupled with MeO‐2PACz through π–π stacking carbazole groups, chelate by forming double C═O···Pb bonds, thus constructing bridge‐connected promote carrier extraction. Simultaneously, fill voids form dense hybrid SAMs, resulting uniform surface potential improved contact. Moreover, treatment also tends induce oriented crystallization films, passivate defects, release lattice stress Consequently, CB‐PA‐based PSCs achieve champion efficiency 25.27% superior operational stability, retaining ≈94% their initial after maximum power point (MPP) tracking (65 °C) for 1000 h ISOS‐L‐2I protocol. This work provides an innovative address challenges high‐performance PSCs.

Language: Английский

Citations

4
"Suspended" Single Rhenium Atoms on Nickel Oxide for Efficient Electrochemical Oxidation of Glucose DOI

Xunzhu Jiang,

Xianhong Wu, Mingyue Lv

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Well-defined single-atom catalysts (SACs) serve as ideal model systems for directly comparing experimental results with theoretical calculations, offering profound insights into heterogeneous catalytic processes. However, precisely designing and controllably synthesizing SACs remain challenging due to the unpredictable structure evolution of active sites generation embedded sites, which may bring about steric hindrance during chemical reactions. Herein, we present precious nonpyrolysis synthesis Re a well-defined phenanthroline coordination supported by NiO (Re1-phen/NiO). Multiple characterizations together calculations unravel idea that isolated atoms are suspended on surface, connected ligands standing perpendicular surface. This unique provides Re1-phen/NiO SAC strong capability activate glucose molecules, enabling fully exposed Re=O double bonds in an open-ended reaction environment simultaneously react hydroxyl aldehyde groups at both ends molecule, rapidly forming glucaric acid.

Language: Английский

Citations

1
Boosting a high-performance desalination in flow-electrode capacitive deionization (FCDI): Unraveling the role of dynamic π − π stacking between a current collector and flow-electrode on enhancing charge transfer DOI
Jianfeng Zhu, Jiani Li, Abing Duan

et al.

Desalination, Journal Year: 2025, Volume and Issue: unknown, P. 118568 - 118568

Published: Jan. 1, 2025

Language: Английский

Citations

1
Humic acid promotes pathway of chloronitrobenzene cathodic reduction shunting from atomic H* to direct electron transfer DOI
Caiqin Wang,

Hangzhe Chen,

Yunjie Zhou

et al.

Water Research, Journal Year: 2024, Volume and Issue: 272, P. 122918 - 122918

Published: Dec. 5, 2024

Language: Английский

Citations

1
Recent nanoengineered therapeutic advancements in sepsis management DOI Creative Commons
Li Liu, Li Li, Ting Wang

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 5, 2024

Sepsis (defined as sepsis 3.0) is a life-threatening organ dysfunction caused by dysregulated host response to variety of pathogenic microorganisms. Characterized high morbidity and mortality, has become global public health problem. However, there lack appropriate diagnostic therapeutic strategies for current management rely on the limited treatment strategies. Recently, nanomedicines targeting controlling release bio-active agents have shown excellent potency in management, with improved efficacy reduced adverse effects. In this review, we summarized advantages nanomaterials. Also, preparation main categories anti-sepsis applied are described detail, including antibiotic-coated nanomaterials, antimicrobial peptides-coated biomimetic nanomaterials macrophages natural products loaded These advances establish huge potential nanomaterials-based especially pharmaceutical pharmacological properties, enhanced efficacy, controllable drug-targeting side To further facilitate clinical translation nanomedicines, propose that issues involving safety, regulatory laws cost-effectiveness should receive much more attention future.

Language: Английский

Citations

0