High Performance and Multi-UV Curable Materials Adaptable Photothermal Nanoparticles for Near-Infrared-Responsive Digital Light Processing Based 4D Printing DOI
Shiwei Feng,

Jingjing Cui,

Yunlong Guo

et al.

Composites Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 110984 - 110984

Published: Nov. 1, 2024

Language: Английский

Vascularized human brain organoids: current possibilities and prospects DOI Creative Commons
Lois Kistemaker, Emma J. van Bodegraven, Helga E. de Vries

et al.

Trends in biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Human brain organoids (hBOs) are in vitro, 3D, self-organizing tissue structures increasingly used for modeling development and disease. Although they traditionally lack vasculature, recent bioengineering developments enable their vascularization, which partly recapitulates neurodevelopmental processes such as neural tube angiogenesis, formation of neurovascular unit (NVU)-like structures, early barriergenesis. vascularized hBOs (vhBOs) already to model (defects in) development, vascularization efficiency other outcomes differ substantially between protocols overall shortcomings should be considered. For instance, vessel-like vhBOs do not contain blood-like flow nor form a functional blood-brain barrier (BBB). Extended characterization, standardization, the new techniques may broader applications drug transport studies.

Language: Английский

Citations

8
Modeling forebrain regional development and connectivity by human brain organoids DOI

Mu Seog Choe,

Cynthia Lo,

In‐Hyun Park

et al.

Current Opinion in Genetics & Development, Journal Year: 2025, Volume and Issue: 91, P. 102324 - 102324

Published: Feb. 20, 2025

Language: Английский

Citations

0
Vascularization of Organoid Microenvironments: Perfusable Networks for Organoid Growth and Maturation DOI Creative Commons
Marc Vila Cuenca, Merve Bulut, Christine L. Mummery

et al.

Current Opinion in Biomedical Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 100586 - 100586

Published: March 1, 2025

Language: Английский

Citations

0
Nanocomposite Hydrogels and Micro/Nanostructures for Printing Organoids DOI

Daixi Xie,

Bingda Chen,

Wenqing Wang

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

Organoids are 3D artificial miniature organs composed of a cluster self-renewing and self-organizing cells in vitro, which mimic the functions real organs. Nanotechnologies, including preparation nanomaterials fabrication micro/nanostructures, have been proven to promote cell proliferation, guide differentiation, regulate self-organization, showing great promise engineering organoids. In this Perspective, different types nanocomposite hydrogels for organoid culture summarized, effects micro/nanostructures on growth development discussed, bioprinting technologies constructing models introduced.

Language: Английский

Citations

0
High Performance and Multi-UV Curable Materials Adaptable Photothermal Nanoparticles for Near-Infrared-Responsive Digital Light Processing Based 4D Printing DOI
Shiwei Feng,

Jingjing Cui,

Yunlong Guo

et al.

Composites Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 110984 - 110984

Published: Nov. 1, 2024

Language: Английский

Citations

1