Acute subdural hematomas in nonagenarians and centenarians DOI
Richard Cook, Laura Zima,

Ryan S. Kitagawa

et al.

Journal of Clinical Neuroscience, Journal Year: 2024, Volume and Issue: 132, P. 110997 - 110997

Published: Dec. 26, 2024

Language: Английский

Carrier-free nanoparticles—new strategy of improving druggability of natural products DOI Creative Commons

Youyun Yao,

Zhenghu Xu, Hang Ding

et al.

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 14, 2025

There are abundant natural products resources and extensive clinical use experience in China. However, the active components of generally have problems such as poor water solubility low bioavailability, which limit their druggability. Carrier-free nanoparticles, nanocrystals, self-assembled extracellular vesicles derived from both animal plant sources, great application potential improving safety efficacy drugs due to simple flexible preparation methods, high drug loading capacity delivery efficiency, well long half-life blood circulation. It has been widely used biomedical fields anti-tumor, anti-bacterial, anti-inflammatory anti-oxidation. Therefore, based on that clinic, this review focuses advantages carrier-free nanoparticles delivering compounds, order improve process vivo draggability.

Language: Английский

Citations

1
Recent Advances and Challenges in Metal Halide Perovskite Quantum Dot-Embedded Hydrogels for Biomedical Application DOI Creative Commons

Junyi Yu,

Chengran Zhang,

Lijun Kong

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(3), P. 643 - 643

Published: Jan. 31, 2025

Metal halide perovskite quantum dots (MHP QDs), as a kind of fluorescent material, have attracted much attention due to their excellent photoluminescence (PL) yield (QY), narrow full width at half maximum (FWHM), broad absorption, and tunable emission wavelength. However, the instability biological incompatibility MHP QDs greatly hinder application in field biomedicine. Hydrogels are three-dimensional polymer networks that widely used biomedicine because high transparency biocompatibility. This review not only introduces latest research progress improving mechanical optical properties hydrogels/MHP but also combines it with existing methods for enhancing stability hydrogels, aiming provide new ideas researchers material selection constructing QD-embedded hydrogels. Finally, prospects future challenges introduced.

Language: Английский

Citations

0
ROS-Triggered Biomimetic Hydrogel Soft Scaffold for Ischemic Stroke Repair DOI
Wen Zhang, Yang Liu,

Yu Wu

et al.

Biomaterials, Journal Year: 2025, Volume and Issue: 319, P. 123217 - 123217

Published: Feb. 25, 2025

Language: Английский

Citations

0
Nanomaterial Technologies for Precision Diagnosis and Treatment of Brain Hemorrhage DOI
Peisen Zhang,

Y. Ran,

Lei Han

et al.

Biomaterials, Journal Year: 2025, Volume and Issue: unknown, P. 123269 - 123269

Published: March 1, 2025

Language: Английский

Citations

0
Injectable glycyrrhizic acid-based hydrogel with Immunoregulatory and angiogenic properties for diabetic wound healing DOI Creative Commons
Haisheng Wu,

Zichao Xue,

Zhigang Wang

et al.

Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113928 - 113928

Published: April 1, 2025

Language: Английский

Citations

0
Injectable dual-network hydrogel for phototherapy and immunomodulation in the treatment of MRSA-infected and diabetic wound DOI

Shengfei Bao,

Aodi Jiang,

Peng Li

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163026 - 163026

Published: April 1, 2025

Language: Английский

Citations

0
Tendon injury repair strategy driven by supramolecular hydrogen bonding and dynamic covalent bond self-assembly microspheres DOI

T. Liu,

Xiaoxuan Ma,

Chenhui Zhu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162726 - 162726

Published: April 1, 2025

Language: Английский

Citations

0
Accessible and Effective Nanomedicines: Self‐Assembly Products From Chinese Herbal Medicines (CHMs) DOI Open Access

Ya‐Lei Wang,

Yan Mu,

Yali Zhang

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Abstract The emergence of nanotechnology has significantly promoted the development medical field, and nanomedicines broadened application potential existing drugs. However, at present, many new types suffer from poor stability, uncertain safety, complex preparation processes, high costs. nano‐ Chinese herbal medicines (CHMs) provided ideas for nanomedicines. Nano‐CHMs are simple to prepare, easily accessible, possess stable reliable safety. This review highlighted nanoparticles with pharmacological activities important material basis CHM formula decoctions. Given composition formulas, article further presented nanoaggregates exosome‐like vesicle nanostructures in single herbs, self‐assembly effect natural compounds. For first time, this systematically introduced characteristics formulas herbs then compounds, nano‐aggregates unclear components structures self‐assembled supramolecular materials. It also summarized problems be solved research CHMs applications, aiming provide guidance modernization ‐related nanoparticles.

Language: Английский

Citations

0
Acute subdural hematomas in nonagenarians and centenarians DOI
Richard Cook, Laura Zima,

Ryan S. Kitagawa

et al.

Journal of Clinical Neuroscience, Journal Year: 2024, Volume and Issue: 132, P. 110997 - 110997

Published: Dec. 26, 2024

Language: Английский

Citations

0