ACS Omega,
Journal Year:
2022,
Volume and Issue:
7(47), P. 42809 - 42818
Published: Nov. 14, 2022
A
Schiff
base
bearing
two
methyl
substituents,
namely,
6,6'-((1E,1'E)-((2,2-dimethylpropane-1,3-diyl)
bis(azanylylidene))
bis(methanylylidene))
bis(2-methylphenol)
[H2AD1Me]
was
synthesized
and
characterized
through
physicochemical
spectroscopic
analyses.
Then,
the
complexed
with
Pd(II)
Ni(II)
to
form
[Pd(AD1Me)]
[Ni(AD1Me)],
respectively.
Both
metal
complexes
were
successfully
obtained
several
analyses,
viz.,
melting
point,
elemental
analysis,
molar
conductivity,
magnetic
susceptibility,
FTIR,
1H
NMR,
UV-vis,
single
crystal
X-ray
diffraction.
quantitative
analysis
of
intermolecular
interactions
in
structures
has
been
performed
using
Hirshfeld
surface
analysis.
crystallized
a
monoclinic
system
space
group
P21/c.
Additionally,
deprotonated
phenolic
oxygen
atom
(O1/O2)
azomethine
nitrogen
(N1/N2)
ligand
chelate
ions,
forming
slightly
distorted
square-planar
complex
containing
three
six-membered
rings
encircling
core
dsp2
hybridization.
The
shift
ν(C=N)
higher
frequency
FTIR
by
26-28
cm-1
indicated
that
complexation
N
established.
It
further
supported
shifting
proton
signal
or
lower
chemical
shifts
Δδ
=
0.43-1.15
ppm
NMR.
In
addition,
n-π*(C=N)
band
UV-vis
spectra
Δλ
24-40
nm
involvement
complexation.
All
compounds
showed
no
significant
antibacterial
activity
against
bacterial
strains,
Staphylococcus
aureus
subsp.
Rosenbach
(ATCC
6538),
Streptococcus
mutans
Clarke
700,610),
Proteus
vulgaris
6380),
as
percent
growth
inhibition
calculated
less
than
90%.
Inorganics,
Journal Year:
2025,
Volume and Issue:
13(4), P. 109 - 109
Published: April 1, 2025
In
order
to
design
antimicrobial
species,
a
series
of
methacrylate
(Macr)
complexes,
[Cu(HBzIm)2(Macr)2]
(1),
[Cu2(HBzIm)2(Macr)4]
(2),
[Cu(2-MeBzIm)2(Macr)2]
(3),
[Cu2(2-MeBzIm)2(Macr)4]
(4),
and
[Cu(5,6-Me2BzIm)2(Macr)2]
(5)
(HBzIm
=
benzimidazole,
2-MeBzIm
2-methylbenzimidazole,
5,6-Me2BzIm
5,6-dimethylbenzimidazole)
were
synthesized
characterized
by
several
spectral
techniques,
as
well
single
crystal
X-ray
diffraction.
The
mononuclear
species
exhibit
distorted
octahedral
stereochemistry,
while
the
binuclear
types,
with
paddle-wheel
structure,
adopt
square
pyramidal
surrounding.
acts
either
chelate
or
bridge,
all
benzimidazole
derivatives
are
coordinated
unidentate.
supramolecular
networks
developed
both
intermolecular
π–π
stacking
interactions
hydrogen
bonds.
assays
provided
complexes
ability
inhibit
planktonic
strain
proliferation,
adhere
on
inert
substratum.
All
moderate
activity,
in
regards
standard
clinical
isolate
strains,
most
active
being
compound
5
against
Candida
albicans,
minimum
inhibitory
concentration
(MIC)
0.156
mg/mL.
It
is
worth
mentioning
that
complex
1
inhibited
microbial
adhesion
Escherichia
coli
2
constrained
C.
albicans
strain.
ACS Omega,
Journal Year:
2022,
Volume and Issue:
7(47), P. 42809 - 42818
Published: Nov. 14, 2022
A
Schiff
base
bearing
two
methyl
substituents,
namely,
6,6'-((1E,1'E)-((2,2-dimethylpropane-1,3-diyl)
bis(azanylylidene))
bis(methanylylidene))
bis(2-methylphenol)
[H2AD1Me]
was
synthesized
and
characterized
through
physicochemical
spectroscopic
analyses.
Then,
the
complexed
with
Pd(II)
Ni(II)
to
form
[Pd(AD1Me)]
[Ni(AD1Me)],
respectively.
Both
metal
complexes
were
successfully
obtained
several
analyses,
viz.,
melting
point,
elemental
analysis,
molar
conductivity,
magnetic
susceptibility,
FTIR,
1H
NMR,
UV-vis,
single
crystal
X-ray
diffraction.
quantitative
analysis
of
intermolecular
interactions
in
structures
has
been
performed
using
Hirshfeld
surface
analysis.
crystallized
a
monoclinic
system
space
group
P21/c.
Additionally,
deprotonated
phenolic
oxygen
atom
(O1/O2)
azomethine
nitrogen
(N1/N2)
ligand
chelate
ions,
forming
slightly
distorted
square-planar
complex
containing
three
six-membered
rings
encircling
core
dsp2
hybridization.
The
shift
ν(C=N)
higher
frequency
FTIR
by
26-28
cm-1
indicated
that
complexation
N
established.
It
further
supported
shifting
proton
signal
or
lower
chemical
shifts
Δδ
=
0.43-1.15
ppm
NMR.
In
addition,
n-π*(C=N)
band
UV-vis
spectra
Δλ
24-40
nm
involvement
complexation.
All
compounds
showed
no
significant
antibacterial
activity
against
bacterial
strains,
Staphylococcus
aureus
subsp.
Rosenbach
(ATCC
6538),
Streptococcus
mutans
Clarke
700,610),
Proteus
vulgaris
6380),
as
percent
growth
inhibition
calculated
less
than
90%.
