Materials,
Journal Year:
2023,
Volume and Issue:
16(18), P. 6143 - 6143
Published: Sept. 9, 2023
This
review
article
explores
the
multiple
applications
and
potential
of
metal-organic
frameworks
(MOFs)
in
biomedical
field.
With
their
highly
versatile
tunable
properties,
MOFs
present
many
possibilities,
including
drug
delivery,
biomolecule
recognition,
biosensors,
immunotherapy.
Their
crystal
structure
allows
precise
tuning,
with
ligand
typology
metal
geometry
playing
critical
roles.
MOFs’
ability
to
encapsulate
drugs
exhibit
pH-triggered
release
makes
them
ideal
candidates
for
precision
medicine,
cancer
treatment.
They
are
also
gene
carriers
genetic
disorders
have
been
used
biosensors
as
contrast
agents
magnetic
resonance
imaging.
Despite
complexities
encountered
modulating
properties
interactions
biological
systems,
further
research
on
is
imperative.
The
primary
focus
this
provide
a
comprehensive
examination
these
applications,
highlighting
current
achievements
encountered.
Such
efforts
will
uncover
untapped
creating
innovative
tools
emphasizing
need
invest
continued
exploration
promising
Bioconjugate Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 7, 2025
Radiotherapy
(RT)
continues
to
encounter
significant
obstacles
such
as
formidable
resistance,
potential
harm
adjacent
healthy
cells,
and
restricted
effectiveness
against
tumors,
resulting
in
a
notable
recurrence
rate.
Therefore,
combining
imaging,
other
treatments,
suitable
enzyme
activity
one
nanoplatform
can
enhance
the
RT
effect
reduce
damage
normal
tissue.
In
this
study,
integrating
hafnium
Prussian
blue
(PB)
nanoparticles
(PB
NPs)
provided
innovative
hafnium-doped
PB
(HPB)
NPs
multifunctional
radiosensitizers.
The
HPB
were
enveloped
by
cancer
cell
membrane,
membrane-camouflaged
(CMHPB)
that
specifically
target
homologous
tumors.
Moreover,
owing
inherent
ability
of
photothermal
therapy
(PTT),
magnetic
resonance
imaging
(MRI),
catalase
(CAT)-like
NPs,
CMHPB
effectively
overcome
tumor
hypoxia
realize
MRI-guided
combined
PTT.
prepared
possessed
uniform
cubic
morphology
with
monodisperse
size
approximately
80
nm
T1
MRI
capability
(r1
=
0.9309
mM-1
S-1).
showed
reliable
PTT
efficiency
CAT-like
vitro
vivo.
Guided
MRI,
be
precisely
delivered
region
for
targeted
destruction
significantly
inhibiting
growth.
used
PTT,
which
address
key
challenges
provide
viable
strategy
enhancing
treatment.
Inorganic Chemistry Frontiers,
Journal Year:
2022,
Volume and Issue:
9(20), P. 5210 - 5216
Published: Jan. 1, 2022
RT
formation
of
Hf
and
Ce
UiO-66
derivatives
is
investigated
using
a
one-step
method
where
the
linker
metal
salt
are
simply
combined,
two-step
inorganic
component
pre-heated
to
form
clusters.
Materials,
Journal Year:
2023,
Volume and Issue:
16(18), P. 6143 - 6143
Published: Sept. 9, 2023
This
review
article
explores
the
multiple
applications
and
potential
of
metal-organic
frameworks
(MOFs)
in
biomedical
field.
With
their
highly
versatile
tunable
properties,
MOFs
present
many
possibilities,
including
drug
delivery,
biomolecule
recognition,
biosensors,
immunotherapy.
Their
crystal
structure
allows
precise
tuning,
with
ligand
typology
metal
geometry
playing
critical
roles.
MOFs’
ability
to
encapsulate
drugs
exhibit
pH-triggered
release
makes
them
ideal
candidates
for
precision
medicine,
cancer
treatment.
They
are
also
gene
carriers
genetic
disorders
have
been
used
biosensors
as
contrast
agents
magnetic
resonance
imaging.
Despite
complexities
encountered
modulating
properties
interactions
biological
systems,
further
research
on
is
imperative.
The
primary
focus
this
provide
a
comprehensive
examination
these
applications,
highlighting
current
achievements
encountered.
Such
efforts
will
uncover
untapped
creating
innovative
tools
emphasizing
need
invest
continued
exploration
promising
