Exploring the effects of counterions and solvents on binuclear and tetranuclear Cu(II) oligo(N,O-donor) salamo-based complexes

Journal of Molecular Structure, Journal Year: 2023, Volume and Issue: 1295, P. 136729 - 136729

Published: Sept. 25, 2023

Language: Английский

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Coordination-Driven Salamo-Salen-Salamo-Type Multinuclear Transition Metal(II) Complexes: Synthesis, Structure, Luminescence, Transformation of Configuration, and Nuclearity Induced by the Acetylacetone Anion

Inorganic Chemistry, Journal Year: 2023, Volume and Issue: 62(25), P. 9945 - 9963

Published: June 13, 2023

A flexible polydentate Salamo-Salen-Salamo hybrid ligand H4L was designed and synthesized, which has rich pockets (salamo salen pockets) so that it may have fascinating coordination patterns with transition metal(II) ions. Four multinuclear complexes, novel butterfly-shaped homotetranuclear [Ni4(L)(μ1-OAc)2(μ1,3-OAc)2(H2O)0.5(CH3CH2OH)3.5]·4CH3CH2OH (1), helical homotrinuclear [Zn3(L)(μ1-OAc)2]·2CH3CH2OH (2), double-helical [Cu2(H2L)2]·2CH3CN (3), mononuclear [Ni(H2L)]·1.5CH3COCH3 (4), been synthesized characterized by single-crystal X-ray diffraction. The effects of different anions [OAc- (O2C5H7)2-] on the complexation behavior ions were studied UV-vis spectrophotometry. fluorescent properties four complexes zebrafish, are expected to be a potential light-emitting material. Ultimately, interaction region indicator (IRI) valuations, Hirshfeld surface analyses, density functional theory (DFT & TD-DFT), electrostatic analyses (ESP), simulations carried out further demonstrate weak interactions electronic free its complexes.

Language: Английский

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In vitro anti-microbial, DNA-binding, In silico pharmacokinetics and molecular docking studies of Schiff-based Cu(II), Zn(II) and Pd(II) complexes

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1315, P. 138695 - 138695

Published: May 25, 2024

Language: Английский

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Antioxidant activity of Schiff base ligands using the DPPH scavenging assay: an updated review

RSC Advances, Journal Year: 2024, Volume and Issue: 14(45), P. 33094 - 33123

Published: Jan. 1, 2024

This review highlights the antioxidant potential of Schiff base ligands via DPPH assay, focusing on structure, solvent effects, and how electron-donating groups enhance radical stabilization, suggesting their role as eco-friendly antioxidants.

Language: Английский

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Solvent-assisted control of the oxidation state in a dinuclear cobalt(II) complex with slow relaxation of the magnetization

Polyhedron, Journal Year: 2025, Volume and Issue: unknown, P. 117425 - 117425

Published: Jan. 1, 2025

Language: Английский

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Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields

Results in Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 102166 - 102166

Published: March 1, 2025

Language: Английский

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Exploring Anticancer Activity and DNA Binding of Metal (II) Salicylaldehyde Schiff Base Complexes: A Convergence of Experimental and Computational Perspectives

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(5)

Published: April 9, 2025

ABSTRACT Metal complexes derived from salicylaldehyde‐based Schiff bases are among the frontrunners in pursuit of precise and potent cancer treatments due to their remarkable prowess. In this study, base ( HL ) was prepared via a reaction between 2‐amino‐5‐benzonitrile salicylaldehyde. Subsequently, further reacted with Ni (II), Co Cu (II) Pd ions using respective metal salts obtain homoleptic mononuclear C1 – C4 ). The composition were determined 1 H 13 C NMR, UV–Vis, FTIR, CHN, SEM–EDX HRMS analyses. addition, structural geometries , C3 solid state single crystal X‐ray diffraction analysis corroborate mentioned characterization techniques employed. stability compounds assessed through time‐dependent UV–vis spectroscopy, revealing that C2 exhibited highest under experimental conditions. anticancer effects tested on breast cell lines (MCF‐7) MTT, LDH ATP assays. Both displayed potential cytotoxicity MCF‐7 line, which better inhibition effect than standard chemotherapeutic agent, doxorubicin (DOX), IC 50 43.08 μM. We postulate mechanism by may function is binding DNA = 0.114 (± 0.02) × 10 4 intercalation (shown UV‐CD UV‐LD spectroscopy) at AT rich sites. These data corroborated silico extra precision (XP) docking molecular dynamic (MD) simulations.

Language: Английский

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Salicylaldehyde-Derived Hydrazones: Synthesis, Characterization, Antibacterial Activity, Antioxidant and Anti-Inflammatory Effects on LPS-Induced RAW264.7 Macrophage Cells, Drug-Likeness Properties, and Molecular Docking Analysis

Biochemical and Biophysical Research Communications, Journal Year: 2025, Volume and Issue: unknown, P. 151872 - 151872

Published: April 1, 2025

Language: Английский

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A new 1D Mn(II) coordination polymer: Synthesis, crystal structure, hirshfeld surface analysis and molecular docking studies

Heliyon, Journal Year: 2024, Volume and Issue: 10(8), P. e29565 - e29565

Published: April 1, 2024

The synthesis of novel metal-organic coordination polymers (MOCP) with the chemical formula [Mn

Language: Английский

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Novel Zn(II) heterobimetallic complexes: synthesis, characterization, density functional theory calculations, in vitro antimicrobial, anti-inflammatory and anticancer activities

Research on Chemical Intermediates, Journal Year: 2024, Volume and Issue: 50(5), P. 2325 - 2355

Published: March 18, 2024

Language: Английский

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