AbstractGreen
synthesis
of
ZnO
nanoparticles
(NPs)
was
performed
from
Salvia
heldreichiana
extract
for
the
first
time.
Synthesized
were
characterized
with
spectroscopic,
microscopic
and
electrochemical
techniques.
Characterization
results
showed
particle
sizes
at
35.98
nm
(±4.29
nm).
Produced
NPs
used
to
modify
3D-printed
electrodes
(3DPE)
without
diallyldimethylammonium
chloride
(DDA).
Modified
determine
dopamine
electrochemically.
Synergistic
effect
between
DDA
observed
resulted
a
high
sensitivity,
broad
linear
range
fit
limit
detection,
respectively,
456.84
µA/mM.cm2,
10-8000
µM
8.56
via
cyclic
voltammetry
method.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Feb. 20, 2024
Abstract
The
current
study
aimed
to
find
an
effective,
simple,
ecological,
and
nontoxic
method
for
bacterial
green
synthesis
of
zinc
oxide
nanoparticles
(ZnONPs)
using
the
strain
Priestia
megaterium
BASMA
2022
(OP572246).
biosynthesis
was
confirmed
by
change
in
color
cell-free
supernatant
added
nitrate
from
yellow
pale
brown.
(Pm/ZnONPs)
were
characterized
UV–Vis
spectroscopy,
high-resolution
transmission
electron
microscopy
(HR-TEM),
energy-dispersive
X-ray
spectroscopy
(EDX),
Fourier
transform
infrared
(FTIR),
zeta
potential.
Pm/ZnONPs
characterization
showed
that
they
have
a
size
ranging
between
5.77
13.9
nm
with
semi-sphere
shape
is
coated
protein-carbohydrate
complex.
An
EDX
analysis
revealed
presence
shield
matrix,
which
composed
carbon,
nitrogen,
oxygen,
chlorine,
potassium,
sodium,
aluminum,
sulfur,
zinc.
results
FTIR
reduction
stabilization
salt
solution
caused
O–H
alcohols
phenols,
O=C=O
stretching
carbon
dioxide,
N=C=S
isothiocyanate,
N–H
bending
amine
functional
groups.
produced
ZnONPs
had
good
stability
charge
−
16.2
mV,
as
evidenced
potential
analysis.
MTT
assay
IC
50
values
8.42%
200%,
respectively,
human
A375
skin
melanoma
bone
marrow
2M-302
cell
lines.
These
findings
obtained
biocompatibility
be
applied
pharmaceutical
biomedical
sectors.
Frontiers in Microbiology,
Journal Year:
2025,
Volume and Issue:
15
Published: Jan. 9, 2025
A
significant
global
health
crisis
is
predicted
to
emerge
due
antimicrobial
resistance
by
2050,
with
an
estimated
10
million
deaths
annually.
Increasing
antibiotic
necessitates
continuous
therapeutic
innovation
as
conventional
treatments
become
increasingly
ineffective.
The
naturally
occurring
antibacterial,
antifungal,
and
antiviral
compounds
offer
a
viable
alternative
synthetic
antibiotics.
This
review
presents
bacterial
mechanisms,
nanocarriers
for
drug
delivery,
plant-based
nanoformulations,
particularly
nanoantibiotics
(nAbts).
Green
synthesis
of
nanoparticles
has
emerged
revolutionary
approach,
it
enhances
the
effectiveness,
specificity,
transport
encapsulated
antimicrobials.
In
addition
minimizing
systemic
side
effects,
these
can
maximize
impact
delivering
antimicrobials
directly
infection
site.
Furthermore,
combining
two
or
more
antibiotics
within
often
exhibits
synergistic
enhancing
effectiveness
against
drug-resistant
bacteria.
Antimicrobial
agents
are
routinely
obtained
from
secondary
metabolites
plants,
including
essential
oils,
phenols,
polyphenols,
alkaloids,
others.
Integrating
antibacterial
antibiotics,
assisted
suitable
codelivery,
potential
solution
addressing
resistance.
increasing
their
boosting
immune
system,
this
approach
provides
safer
effective
method
tackling
future
infections.
Beilstein Journal of Nanotechnology,
Journal Year:
2025,
Volume and Issue:
16, P. 78 - 89
Published: Jan. 30, 2025
The
fundamental
goal
of
our
investigation
is
to
employ
a
sustainable
synthesis
method
for
zinc
oxide
nanoparticles
(ZnO
NPs),
utilizing
lactic
acid
bacteria
isolated
from
curd
as
the
key
biological
agent.
Bacteria
function
agents
both
reduction
and
capping
processes,
which
aids
ZnO
NPs.
Various
characterization
techniques
including
XRD,
FTIR,
UV–vis,
TEM,
SEM-EDX,
zeta
potential
measurements
were
employed
analyze
morphology,
dimensions,
elemental
composition
generated
nanoparticles.
experimental
outcomes
confirmed
presence
hexagonal
wurtzite-structured
NPs
with
an
average
size
10
nm.
colloidal
system
demonstrated
excellent
stability
−60
mV.
Furthermore,
synthesized
displayed
significant
antibacterial
activity
against
selected
human
pathogens,
biggest
inhibition
zone
observed
Staphylococcus
aureus
(22
±
0.57
mm)
smallest
Salmonella
enterica
serovar
typhi
(3
1
mm).
MTT
assay
revealed
promising
antiproliferative
NPs,
IC
50
value
98.53
µg/mL.
Additionally,
photocatalytically
electrochemically
analyzed,
indicating
their
use
in
cancer
research
well
coating
drug
delivery
applications.
Results in Chemistry,
Journal Year:
2024,
Volume and Issue:
7, P. 101417 - 101417
Published: Jan. 1, 2024
Green
synthetic
methods
are
currently
preferred
in
industry
over
other
physicochemical
methods.
Herein,
we
present
a
facile,
environmentally
friendly,
non-toxic
approach
for
the
fabrication
of
MgO
using
jamun
fruit
extract.
The
phytochemicals
extract,
such
as
kaemferol,
glucoside,
anthocyanins,
ellagic
acid,
myricetin,
and
isoquercetin,
facilitate
bio-reduction
Mg(NO3)2.
Pure
Sm3+
(1–7
mol
%)
doped
nanomaterials
were
synthesized
this
bio-mediated
method.
structural
morphological
properties
studied
Powder
X-ray
diffraction
(PXRD),
Field
Emission
Scanning
Electron
Microscopy
(FE-SEM),
Energy
Dispersive
Spectroscopy
(EDS),
Diffused
Reflectance
(DRS)
techniques.
effect
ions
on
host
matrix
photo-catalytic
oxidation
Fast
Orange-Red
(FOR)
dye
was
investigated
under
UV
light
irradiation.
MgO:
Sm3+(3
exhibited
superior
(94
degradation
compared
to
pristine
catalysts,
attributed
maximum
migration
charge
carriers
at
catalyst's
surface.
Additionally,
3
%
electrode
demonstrated
smaller
transfer
resistance,
indicating
capacitive
electrodes.
materials
also
effective
bactericidal
activity
against
pathogens.
This
research
demonstrates
potential
environmental
pollution
purification,
well
their
utility
supercapacitors,
batteries,
sensors,
antibacterial
applications.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Aug. 24, 2024
Abstract
In
this
study,
Ziziphus
spina
christi
leaves
was
used
to
synthesize
a
trimetallic
CuO/Ag/ZnO
nanocomposite
by
simple
and
green
method.
Many
characterizations
e.g.
FTIR,
UV–vis
DRS,
SEM–EDX,
TEM,
XRD,
zeta-size
analysis,
DLS,
were
confirm
green-synthesized
nanocomposite.
The
green,
synthesized
exhibited
spherical
dot-like
structure,
with
an
average
particle
size
of
around
7.11
±
0.67
nm
zeta
potential
21.5
mV.
An
extremely
homogeneous
distribution
signals,
including
O
(79.25%),
Cu
(13.78%),
Zn
(4.42%),
Ag
(2.55%),
is
evident
on
the
surface
green-synthetic
nanocomposite,
according
EDX
data.
To
best
our
knowledge,
first
study
effectively
use
industrially
produced
as
potent
antimicrobial
agent
employing
different
statistically
experimental
designs.
highest
yield
synthetic
(1.65
mg/mL),
which
enhanced
1.85
5.7
times;
respectively,
using
Taguchi
approach
in
comparison
Plackett–Burman
strategy
basal
condition.
A
variety
assays
techniques
utilized
evaluate
capabilities
at
200
µg/mL
concentration
against
multidrug-resistant
human
pathogens.
After
36-h
period,
tested
reduced
planktonic
viable
counts
studied
bacteria,
Escherichia
coli
Staphylococcus
aureus
,
showed
percentage
biofilm
reduction
(98.06
0.93
97.47
0.65%;
respectively).
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(17), P. 9500 - 9500
Published: Aug. 31, 2024
Nanotechnology
has
gained
popularity
in
recent
years
due
to
its
wide-ranging
applications
within
the
scientific
community.
The
three
main
methods
for
synthesizing
nanoparticles
are
physical,
chemical,
and
biological.
However,
adverse
effects
associated
with
physical
chemical
have
led
a
growing
interest
biological
methods.
Interestingly,
green
synthesis
using
plants
prominence
developing
new
treatments
bacterial
infections.
Zinc
oxide
(ZnO
NPs)
produced
environmentally
friendly
more
biocompatible
potential
as
antibacterial
agents
biomedical
field.
As
result,
this
review
discusses
of
ZnO
NPs,
factors
influencing
optimal
synthesis,
characterization
techniques,
activity
some
plant-mediated
NPs.
It
also
provides
comprehensive
analytical
exploration
NP
biosynthesis,
role
phytochemical
compounds
reducing
stabilizing
agents,
mechanism
action
their
properties
further
highlights
challenges
prospects
innovative
research
area.