A Lewis Acid‐Base Pair Catalyzed Dearomative Transformation of Unprotected Indoles via B−H Bond Activation DOI Open Access
Pinaki Nad, Arup Mukherjee

Chemistry - An Asian Journal, Journal Year: 2023, Volume and Issue: 18(23)

Published: Oct. 9, 2023

A sustainable and metal-free protocol has been described for the reduction of unprotected indoles. The catalytic system consists B(C6 F5 )3 THF as a Lewis acid-base pair that can activate B-H bond pincolborane (HBpin). encompasses broad substrate scope. Control experiments were conducted to understand possible intermediates involved during present protocol.

Language: Английский

Base-free palladium-catalyzed borylation of enol carboxylates and further reactivity toward deboronation and cross-coupling DOI

Gregory Gaube,

Douglas L. Miller, R. W. McCallum

et al.

Tetrahedron, Journal Year: 2025, Volume and Issue: unknown, P. 134682 - 134682

Published: May 1, 2025

Language: Английский

Citations

0
Boron-Catalyzed Formylation of Indoles Using Trimethyl Orthoformate as Carbonyl Source DOI Creative Commons

Kiratipong Charoensawas,

Jirapat Yimyaem,

Uthaiwan Sirion

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

Language: Английский

Citations

0
Recent Advances on Regioselective C−H Borylation of Indoles DOI

Yanyan Guo,

Meiyu Wang, Guodu Liu

et al.

Asian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 9, 2024

Abstract Borylated indoles are versatile building blocks for functional molecules, such as pharmaceutical and natural products. However, the C−H borylation regioselectivity of unprotected with seven distinct sites has been a problem long time. Among various synthetic approaches to borylated indoles, transition‐metal‐catalyzed, electrophilic chelation effect directed attractive methods because their powerful ability rapidly construct indoles. In this review, we highlight developments in indole using these over last 20 years. With focus on mechanism indole, further studies field would be inspired future.

Language: Английский

Citations

1
Five-membered ring systems: Pyrroles and benzo analogs DOI
Chuan Shan, Justin M. Lopchuk

Progress in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 123 - 173

Published: Jan. 1, 2024

Language: Английский

Citations

0
A Lewis Acid‐Base Pair Catalyzed Dearomative Transformation of Unprotected Indoles via B−H Bond Activation DOI Open Access
Pinaki Nad, Arup Mukherjee

Chemistry - An Asian Journal, Journal Year: 2023, Volume and Issue: 18(23)

Published: Oct. 9, 2023

A sustainable and metal-free protocol has been described for the reduction of unprotected indoles. The catalytic system consists B(C6 F5 )3 THF as a Lewis acid-base pair that can activate B-H bond pincolborane (HBpin). encompasses broad substrate scope. Control experiments were conducted to understand possible intermediates involved during present protocol.

Language: Английский

Citations

0