International Journal of Child Health and Nutrition,
Journal Year:
2025,
Volume and Issue:
14(2), P. 92 - 104
Published: May 16, 2025
Purpose:
The
article
aimed
to
study
modern
approaches
the
desensitization
of
pet
allergens,
focusing
on
advanced
therapeutic
and
diagnostic
methods
for
managing
preventing
allergic
reactions
in
children
adults.
Material
Methods:
used
a
theoretical
analysis
scientific
sources
covering
molecular
mechanisms
allergy,
methods,
strategies.
Results:
Global
trends
prevalence
allergies
were
examined,
role
diagnostics
latest
such
as
allergen-specific
immunotherapy
(ASIT),
was
assessed,
comparison
traditional
innovative
treatment
made.
findings
demonstrate
that
allergy
is
globally
widespread
problem
affecting
20-30%
population
developed
countries,
with
highest
rates
among
urban
populations.
It
has
been
established
mechanisms,
particular
Fel
d
1
Can
f
1,
are
key
developing
an
reaction,
which
opens
up
opportunities
new
approaches.
Modern
approaches,
including
component
analysis,
basophil
activation
test,
multiplex
tests,
accurately
detect
allergens
determine
severe
reaction
risk.
Numerous
clinical
researches
have
indicated
ASIT
utilizing
modified
reduces
symptoms
people
sensitization.
Conclusion:
These
results
highlight
importance
introducing
personalized
therapy
animal
allergies.
This
prospects
improving
patients’
lives
reducing
socioeconomic
burden
diseases.
Over
the
years,
oral
and
maxillofacial
injuries,
mainly
caries,
pulpitis,
bone
defects,
cancer,
often
involve
a
variety
of
organs
tissues,
resulting
in
structural
dysfunction,
adverse
effects
on
facial
appearance,
not
only
affecting
people's
chewing,
swallowing
other
physiological
functions,
but
also
to
physical
mental
health
burden.
As
type
carbon-based
nanomaterial,
carbon
dots
(CDs)
have
been
widely
used
diagnosis
treatment
diseases
due
its
excellent
optical
properties,
good
biocompatibility
low
toxicity.
In
addition,
surface
functionalization
or
passivation
CDs
can
change
properties
CDs,
such
as
water
solubility
chemiluminescence,
broaden
biomedical
potential
CDs.
this
review,
latest
research
progress
modified
hard
tissue
regeneration,
tumor
treatment,
antibacterial
activity,
dentin
pulp
complex
teeth
whitening,
wound
healing,
drug
release,
fluorescence
tracer
bioimaging
were
reviewed.
we
discussed
problems
future
direction
development.
Abstract
Water-soluble
fluorescent
N-doped
carbon
quantum
dots
(N-CQDs)
were
hydrothermally
prepared
through
a
green
synthesis
route
using
castor
seeds
as
single
precursor
and
hydrothermal
method.
Several
experimental
techniques
have
been
used
to
characterize
synthesized
N-CQDs
confirm
their
structure
verify
applicability
in
cell
imaging
pH
sensing.
The
found
are
characterized
by
amorphous
nature
with
spherical
shape
an
average
particle
size
of
6.57
nm
revealed
from
XRD
TEM
measurements.
FTIR
results
reveal
the
presence
carboxylic
hydroxyl
functional
groups
on
surface
CQDs,
which
was
also
confirmed
XPS
analysis.
fluorescence
characterization
showed
blue
emission
excitation
dependence.
It
that
optimal
wavelengths
360
432
nm,
respectively.
Moreover,
intensity
good
linear
dependence
values
ranges
3.5
−
7.5
sand
8
12
well
high
sensitivity
for
slight
changes
values.
According
these
results,
two
sensors
created
based
acidic
basic
media.
obtained
zeta
potential
-21.86
mV
thus
excellent
stability
water.
derived
antimicrobial
activity
exhibits
low
cytotoxicity
WI-13
cells
IC50
=
394.4
±
13.8
µg/mL.
this
study
demonstrated
can
be
sensing
materials.
On
other
hand,
they
promising
applications
imaging,
thermo-sensing
optoelectronics.
