The impact of air pollution on neurodegenerative diseases: a narrative review of current evidence
The Egyptian Journal of Internal Medicine,
Journal Year:
2025,
Volume and Issue:
37(1)
Published: Jan. 24, 2025
Abstract
This
narrative
review
explores
the
relationship
between
air
pollution
and
neurodegenerative
diseases
(NDs).
Historically,
has
been
linked
primarily
to
respiratory
cardiovascular
issues,
but
recent
evidence
suggests
that
it
may
also
impact
neurological
health.
With
global
increase
in
diseases,
understanding
environmental
risk
factors
become
crucial.
The
synthesizes
findings
from
studies,
highlighting
potential
role
of
pollutants—particularly
fine
particulate
matter
(PM2.5),
ozone,
nitrogen
dioxide
(NO2),
heavy
metals—in
onset
progression
NDs.
Key
mechanisms
under
investigation
include
brain
inflammation
microglial
activation,
which
are
believed
contribute
processes.
Animal
human
studies
have
shown
correlations
exposure
increased
cognitive
decline
disorders.
Research
indicates
exacerbate
neuroinflammation
cause
white
abnormalities,
disrupt
neural
communication
function.
Additionally,
emerging
like
residential
greenness
climate
action
could
mitigate
some
these
adverse
effects.
Despite
advancements,
significant
knowledge
gaps
remain,
particularly
regarding
long-term
chronic
specific
molecular
pathways
involved.
shows
need
for
further
research
clarify
develop
targeted
interventions.
Addressing
pollution’s
on
requires
comprehensive
public
health
strategies,
including
stricter
regulations
awareness,
alongside
continued
into
preventive
therapeutic
measures.
Language: Английский
Alzheimer’s Disease Dementia Prevalence in the United States: A County-Level Spatial Machine Learning Analysis
American Journal of Alzheimer s Disease & Other Dementias®,
Journal Year:
2025,
Volume and Issue:
40
Published: April 1, 2025
A
growing
body
of
literature
has
examined
the
impact
neighborhood
characteristics
on
Alzheimer’s
disease
(AD)
dementia,
yet
spatial
variability
and
relative
importance
most
influential
factors
remain
underexplored.
We
compiled
various
widely
recognized
to
examine
heterogeneity
associations
with
AD
dementia
prevalence
via
geographically
weighted
random
forest
(GWRF)
approach.
The
GWRF
outperformed
conventional
models
an
out-of-bag
R
2
74.8%
in
predicting
lowest
error
(MAE
=
0.34,
RMSE
0.45).
Key
findings
showed
that
mobile
homes
were
factor
19.9%
U.S.
counties,
followed
by
NDVI
(17.4%),
physical
inactivity
(12.9%),
households
no
vehicle
(11.3%),
particulate
matter
(10.4%),
while
other
primary
affecting
<10%
counties.
Findings
highlight
need
for
county-specific
interventions
tailored
local
risk
factors.
Policies
should
prioritize
increasing
affordable
housing
stability,
expanding
green
spaces,
improving
transportation
access,
promoting
activity,
reducing
air
pollution
exposure.
Language: Английский
ViTBayesianNet: An adaptive deep bayesian network-aided alzheimer disease detection framework with vision transformer-based residual densenet for feature extraction using MRI images
Network Computation in Neural Systems,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 41
Published: Dec. 11, 2024
One
of
the
most
familiar
types
disease
is
Alzheimer's
(AD)
and
it
mainly
impacts
people
over
age
limit
60.
AD
causes
irreversible
brain
damage
in
humans.
It
difficult
to
recognize
various
stages
AD,
hence
advanced
deep
learning
methods
are
suggested
for
recognizing
its
initial
stages.
In
this
experiment,
an
effective
model-based
detection
approach
introduced
provide
treatment
patient.
Initially,
essential
MRI
collected
from
benchmark
resources.
After
that,
gathered
MRIs
provided
as
input
feature
extraction
phase.
Also,
important
features
image
extracted
by
Vision
Transformer-based
Residual
DenseNet
(ViT-ResDenseNet).
Later,
retrieved
applied
stage.
phase,
detected
using
Adaptive
Deep
Bayesian
Network
(Ada-DBN).
Additionally,
attributes
Ada-DBN
optimized
with
help
Enhanced
Golf
Optimization
Algorithm
(EGOA).
So,
implemented
model
accomplishes
relatively
higher
reliability
than
existing
techniques.
The
numerical
results
framework
obtained
accuracy
value
96.35
which
greater
91.08,
91.95,
93.95
attained
EfficientNet-B2,
TF-
CNN,
ViT-GRU,
respectively.
Language: Английский