Tetrahedron Chem, Journal Year: 2024, Volume and Issue: unknown, P. 100104 - 100104
Published: Oct. 1, 2024
Language: Английский
ACS Organic & Inorganic Au, Journal Year: 2024, Volume and Issue: 4(5), P. 471 - 484
Published: June 21, 2024
The electrochemical oxidation of amines to nitriles and imines represents a critical frontier in organic electrochemistry, offering sustainable pathway these valuable compounds. Nitriles are pivotal various industrial applications, including pharmaceuticals, agrochemicals, materials science. This review encapsulates the recent advancements electrooxidation process, emphasizing mechanistic understanding, electrode material innovations, optimization reaction conditions, exploration solvent electrolyte systems. Additionally, addresses operational parameters that significantly affect such as current density, temperature, surface, insights into their for enhanced performance. By providing comprehensive view state prospects amine imines, this aims inspire further development, innovation, research promising area green chemistry.
Language: Английский
Citations
9
Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(14), P. 3050 - 3084
Published: May 22, 2024
Abstract Tetrahydro‐ β ‐carbolines (TH Cs) also known as tryptolines serve important structural elements in natural products and pharmaceutical compounds, they are utilized drug discovery. They display diverse bioactivities, including anticancer, antifungal, antiparasitic, anti‐ischemic, anti‐inflammatory, other activities. Besides their pharmacological biological significance, these motifs extensively used the production of bioactive compounds. This review is intended to summarize recent advancements chemistry this compound class, synthesis applications organic synthetic intermediates molecules.
Language: Английский
Citations
5
BMC Chemistry, Journal Year: 2024, Volume and Issue: 18(1)
Published: July 27, 2024
Abstract In this study, a new green method was developed for the synthesis of bis(indolyl)methane derivatives using electrochemical bisarylation reaction in deep eutectic solvents as alternative to traditional and electrolytes. The effects varying time, current, type solvent material electrodes were all studied. optimum conditions involved use ethylene glycol/choline chloride with ratio 2:1 at 80 °C 45 min. Graphite platinum used cathode anode, respectively. newly offered many advantages such mild conditions, short time affording high product yields wide range substituted aromatic aldehydes bearing electron donating or withdrawing substituents. addition, proved be more effective than heating afforded higher products shorter time. mechanism proposed confirmed cyclic voltammetry study.
Language: Английский
Citations
1
Beilstein Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 20, P. 2217 - 2224
Published: Sept. 2, 2024
Electrosynthesis is a technique that attracting increased attention and has many appealing features, particularly its potential greenness. At the same time, electrosynthesis requires solvent supporting electrolyte in order for current to pass through reaction. These are effectively consumable reagents unless convenient means of recycling can be developed. As part our interest unusual solvents electrochemistry, we explored application simple, inexpensive, recyclable deep eutectic allylation carbonyls. While several sets conditions were developed, goal avoiding stoichiometric amounts metal proven elusive. Still, used plate out thus recover used, offering an interesting new option electrochemical allylations.
Language: Английский
Citations
0
Tetrahedron Chem, Journal Year: 2024, Volume and Issue: unknown, P. 100104 - 100104
Published: Oct. 1, 2024
Language: Английский
Citations
0