Novel β-Benzyloxy-Substituted Copolymers of Seven-Membered Cyclic Carbonate: Ring-Opening Polymerization with L-Lactide, ε-Caprolactone and Trimethylenecarbonate DOI Open Access
Valeriia A. Serova, Badma N. Mankaev,

Milana U. Agaeva

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3364 - 3364

Published: Nov. 29, 2024

To prepare novel biodegradable copolymers with functional substituents that are distributed statistically or randomly over the macromolecule chain and have improved characteristics compared to homopolymers, we conducted a series of synthetic experiments cyclic monomer, 5-(benzyloxy)-1,3-dioxepan-2-one (

Language: Английский

Synthesis and Ring-Opening Polymerization of Bisubstituted ε-Caprolactones Bearing Aryl and Cyano Groups DOI
Pengfei Gao,

Hong-Ran Wang,

Xiang-Xi Xiao

et al.

Polymer, Journal Year: 2025, Volume and Issue: unknown, P. 128034 - 128034

Published: Jan. 1, 2025

Language: Английский

Citations

0
Kinetic investigation and scale-up of bulk ring-opening copolymerization of L-lactide and ɛ-caprolactone in the presence of liquid tin(II) n-butoxide DOI
Montira Sriyai,

Tawan Chaiwon,

Puttinan Meepowpan

et al.

Polymer Bulletin, Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

Language: Английский

Citations

0
Exploration of a Novel Catalytic Approach for Synthesizing Glycolide and ε-Caprolactone Copolymers and Their Application as Carriers for Paclitaxel DOI Creative Commons
Rafał Wyrębiak, Ramona Figat, Ewa Olędzka

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(11), P. 2318 - 2318

Published: May 25, 2025

Biodegradable polyesters serve as matrices in pharmaceutical applications for the controlled release of therapeutic agents. These polymers are essential advancement drug delivery systems (DDSs) that facilitate gradual over a predetermined duration. Therefore, this study introduces novel use diethyl zinc/propyl gallate catalytic system to synthesize glycolide/ε-caprolactone copolymers (PGCL) subsequent biomedical applications. A total twenty-four biodegradable copolymeric matrices, characterized by highly random microstructure and an average molecular weight (Mn) ranging from approximately 27 62 kDa, were synthesized analyzed. The resulting copolymer samples underwent Neutral Red Uptake (NRU) Umu tests, revealing no signs cyto- or genotoxicity. Furthermore, hemolysis assay was conducted on selected samples, indicating their suitability intravenous administration. Finally, paclitaxel (PACL) one demonstrated sustained profile, following first-order kinetics Fickian diffusion mechanism.

Language: Английский

Citations

0
Polycaprolactone (PCL): the biodegradable polyester shaping the future of materials – a review on synthesis, properties, biodegradation, applications and future perspectives DOI Creative Commons

Maria Angeliki G. Ntrivala,

A. Pitsavas,

Kyriaki Lazaridou

et al.

European Polymer Journal, Journal Year: 2025, Volume and Issue: unknown, P. 114033 - 114033

Published: May 1, 2025

Language: Английский

Citations

0
Triazine Mg-Based Phosphonate Metal–Organic Framework for ε-Caprolactone Polymerization DOI
Rubén Serrano-Nieto, Christian Rentero, Pablo Salcedo‐Abraira

et al.

Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: June 4, 2025

A novel three-dimensional metal-organic framework (MOF) based on magnesium and the triazine triphosphonate ligand has been successfully synthesized via solvothermal method fully characterized. Denoted as IEF-31 (IEF stands for IMDEA energy framework), its crystal structure was unveiled by single-crystal X-ray diffraction, exhibiting free P-OH groups in two coordination modes (-PO3H2 -PO3H) an open with 1D channels (8 × 7 Å). This robust shows high thermal chemical stability (in several catalytic-relevant organic solvents water, pH = 2 to 10). Further, this study presents proof of concept using Mg-based P-MOF a catalyst ring-opening polymerization ε-caprolactone (ε-CL) relevance challenging bioplastic formation. Specifically, IEF-31(Mg) achieved notable monomer conversions polymer molecular weights low dispersity values (Đ ≈ 1.1), paving way further design optimization robust, efficient, sustainable Mg P-MOFs clean processes.

Language: Английский

Citations

0
A Theoretical Exploration of Monomer Activation Mechanisms in Bis-Lithium N-Heterocyclic Carbenes Complexes for Enhanced Understanding of Charge Distribution in Ring-Opening Polymerization of ε-Caprolactone DOI
Nathaporn Cheechana, Natthapol Akkravijitkul, Nopawit Khamto

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 140113 - 140113

Published: Sept. 1, 2024

Language: Английский

Citations

0
Novel β-Benzyloxy-Substituted Copolymers of Seven-Membered Cyclic Carbonate: Ring-Opening Polymerization with L-Lactide, ε-Caprolactone and Trimethylenecarbonate DOI Open Access
Valeriia A. Serova, Badma N. Mankaev,

Milana U. Agaeva

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3364 - 3364

Published: Nov. 29, 2024

To prepare novel biodegradable copolymers with functional substituents that are distributed statistically or randomly over the macromolecule chain and have improved characteristics compared to homopolymers, we conducted a series of synthetic experiments cyclic monomer, 5-(benzyloxy)-1,3-dioxepan-2-one (

Language: Английский

Citations

0