Construction of Phosphonyl and Sulfonyl 3‐Methylene‐Oxindoles via Nucleophilic Vinylic Substitution DOI Open Access
Zhen Chen,

Xiao-Li Zhu,

Mengyuan Wu

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(11)

Published: March 1, 2025

Abstract 3‐Methylene‐substituted oxindoles play crucial roles as pharmaceutically important reagents well valuable synthons in medicinal and organic synthesis. In this study, a uniform nucleophilic vinylic substitution (S N V) reaction for the construction of phosphonyl sulfonyl substituted 3‐methylene‐oxindole was developed with application ( E )‐3‐(nitromethylene) oxindole powerful precursor. addition, preliminary study revealed that these have potential applications both constructing intriguing molecules serving antibacterial agents.

Language: Английский

A review on recent progress in synthesis and biological activities of spiropyrrolidine and its derivatives DOI
A. F. M. Motiur Rahman,

Md. Zafer Alam,

A.H.M.M. Jahan

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141377 - 141377

Published: Jan. 1, 2025

Language: Английский

Citations

3
Construction of Phosphonyl and Sulfonyl 3‐Methylene‐Oxindoles via Nucleophilic Vinylic Substitution DOI Open Access
Zhen Chen,

Xiao-Li Zhu,

Mengyuan Wu

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(11)

Published: March 1, 2025

Abstract 3‐Methylene‐substituted oxindoles play crucial roles as pharmaceutically important reagents well valuable synthons in medicinal and organic synthesis. In this study, a uniform nucleophilic vinylic substitution (S N V) reaction for the construction of phosphonyl sulfonyl substituted 3‐methylene‐oxindole was developed with application ( E )‐3‐(nitromethylene) oxindole powerful precursor. addition, preliminary study revealed that these have potential applications both constructing intriguing molecules serving antibacterial agents.

Language: Английский

Citations

0