Silver Nanoparticle-Infused Bone Cement: Innovations in Orthopedic Biomaterials DOI Open Access
Sudip Mandal

International Journal of Scientific Research in Science and Technology, Journal Year: 2024, Volume and Issue: 11(6), P. 826 - 840

Published: Dec. 27, 2024

The integration of silver nanoparticles (AgNPs) into bone cement has emerged as a cutting-edge approach to enhance the functional properties orthopedic biomaterials. Silver nanoparticles, known for their broad-spectrum antimicrobial properties, provide an innovative solution combat implant-associated infections. This review delves synthesis methods, including in situ formation and physical blending, examines performance AgNP-infused terms efficacy, mechanical strength, biocompatibility. By addressing challenges such cytotoxicity regulatory considerations, this analysis highlights its transformative potential reducing infection rates, enhancing implant longevity, ultimately improving patient outcomes surgeries.

Language: Английский

Eco-friendly additives for biodegradable polyesters: Recent progress in performance optimization and environmental impact reduction DOI Creative Commons
Ahmad Fayyazbakhsh, Nima Hajinajaf, Hamed Bakhtiari

et al.

Sustainable materials and technologies, Journal Year: 2025, Volume and Issue: unknown, P. e01395 - e01395

Published: April 1, 2025

Language: Английский

Citations

0

Advances in Wearable Biosensors for Wound Healing and Infection Monitoring DOI Creative Commons
Dang-Khoa Vo, Kieu The Loan Trinh

Biosensors, Journal Year: 2025, Volume and Issue: 15(3), P. 139 - 139

Published: Feb. 23, 2025

Wound healing is a complicated biological process that important for restoring tissue integrity and function after injury. Infection, usually due to bacterial colonization, significantly complicates this by hindering the course of enhancing chances systemic complications. Recent advances in wearable biosensors have transformed wound care making real-time monitoring biomarkers such as pH, temperature, moisture, infection-related metabolites like trimethylamine uric acid. This review focuses on recent biosensor technologies designed management. Novel sensor architectures, flexible stretchable electronics, colorimetric patches, electrochemical platforms, enable non-invasive detection changes associated with wounds high specificity sensitivity. These are increasingly combined AI analytics based smartphones can timely personalized interventions. Examples PETAL patch applies multiple sensing mechanisms wide-ranging views status closed-loop systems connect therapeutic devices automate infection control. Additionally, self-powered tap into body heat or energy from biofluids themselves avoid any external batteries thus more effective field use limited resources. Internet Things connectivity allows further support remote sharing data, supporting telemedicine applications. Although developed relatively rapidly their prospects continue expand, regular clinical application stalled significant challenges regulatory, cost, patient compliance, technical problems related accuracy, biofouling, power, among others, need be addressed innovative solutions. The goal synthesize current trends, challenges, future directions monitoring, emphasis potential improve outcomes reduce healthcare burdens. innovations leading way toward next-generation bridging advanced materials science, biotechnology, digital health.

Language: Английский

Citations

0

Pharmaceutical 3D Printing Technology Integrating Nanomaterials and Nanodevices for Precision Neurological Therapies DOI Creative Commons
Jurga Bernatonienė,

Mindaugas Plieskis,

Kęstutis Petrikonis

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 352 - 352

Published: March 9, 2025

Pharmaceutical 3D printing, combined with nanomaterials and nanodevices, presents a transformative approach to precision medicine for treating neurological diseases. This technology enables the creation of tailored dosage forms controlled release profiles, enhancing drug delivery across blood−brain barrier (BBB). The integration nanoparticles, such as poly lactic-co-glycolic acid (PLGA), chitosan, metallic nanomaterials, into 3D-printed scaffolds improves treatment efficacy by providing targeted prolonged release. Recent advances have demonstrated potential these systems in conditions like Parkinson’s disease, epilepsy, brain tumors. Moreover, printing allows multi-drug combinations personalized formulations that adapt individual patient needs. Novel approaches, including stimuli-responsive systems, on-demand dosing, theragnostics, provide new possibilities real-time monitoring disorders. Despite innovations, challenges remain terms scalability, regulatory approval, long-term safety. future perspectives this suggest its revolutionize treatments offering patient-specific therapies, improved penetration, enhanced outcomes. review discusses current state, applications, nanotechnology treatment, highlighting need further research overcome existing challenges.

Language: Английский

Citations

0

Antimicrobial Effect of Silver Nanoparticles as a Potential Healing Treatment for Wounds Contaminated with Staphylococcus aureus in Wistar Rats DOI
Franciele Garcia Baveloni, Andréía Bagliotti Meneguin, Rafael Miguel Sábio

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 106445 - 106445

Published: Nov. 1, 2024

Language: Английский

Citations

1

3D Printing in Wound Healing: Innovations, Applications, and Future Directions DOI Open Access
Rahul Ashok Sachdeo, Chitra Khanwelkar, Amol Shete

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 8, 2024

The field of wound healing faces significant challenges, particularly in the treatment chronic wounds, which often result prolonged times and complications. Recent advancements 3D printing technology have provided innovative solutions to these offering tailored precise approaches care. This review highlights role enhancing healing, focusing on its application creating biocompatible scaffolds, custom dressings, drug delivery systems. By mimicking extracellular matrix (ECM) facilitating cell proliferation, 3D-printed biomaterials potential significantly accelerate process. In addition, bioprinting enables production functional skin substitutes that can be customized for individual patients. Despite promise technologies, several challenges remain, including need improved vascularization, cost concerns, regulatory hurdles. future lies continued integration with emerging technologies such as 4D bioelectronics, providing opportunities personalized on-demand therapies. explores current state care, technologies.

Language: Английский

Citations

1

Silver Nanoparticle-Infused Bone Cement: Innovations in Orthopedic Biomaterials DOI Open Access
Sudip Mandal

International Journal of Scientific Research in Science and Technology, Journal Year: 2024, Volume and Issue: 11(6), P. 826 - 840

Published: Dec. 27, 2024

The integration of silver nanoparticles (AgNPs) into bone cement has emerged as a cutting-edge approach to enhance the functional properties orthopedic biomaterials. Silver nanoparticles, known for their broad-spectrum antimicrobial properties, provide an innovative solution combat implant-associated infections. This review delves synthesis methods, including in situ formation and physical blending, examines performance AgNP-infused terms efficacy, mechanical strength, biocompatibility. By addressing challenges such cytotoxicity regulatory considerations, this analysis highlights its transformative potential reducing infection rates, enhancing implant longevity, ultimately improving patient outcomes surgeries.

Language: Английский

Citations

0