A Universal Method for the Simultaneous Determination of Environmental Pollutants in Marine Biological Samples: Per- and Polyfluoroalkyl Substances and Antibiotics as a Case Study DOI
Di Fang, Yang Ge, Bentuo Xu

et al.

ACS ES&T Water, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Conventional detection technologies for environmental contaminants have primarily focused on providing accurate qualitative and quantitative evaluations single pollutant types, leading to increased costs an inability satisfy the growing demand detecting a broader spectrum of pollutants. Here, we introduced novel analytical method simultaneously measure concentration levels diverse pollutants, characterized by their distinct properties, across complex biological samples. Per- polyfluoroalkyl substances (PFAS) antibiotics were used as case study due frequency in environment known impacts Our harnesses salting-out effect sodium chloride proteins within muscle tissues 178 marine species, which significantly reduces addition extraneous substances, mitigates matrix interference, avoids reliance solid-phase extraction or dispersive agents. The provides simultaneous pretreatment several compounds, with limits from 0.002 0.41 ng/g dry weight, are substantially lower than conventional methods. Overall, this streamlines efficiency, decreases costs, lessens effects, sets solid groundwork future applications concurrent environmentally pertinent pollutants varied characteristics.

Language: Английский

In Situ Ag-Seeded Lamellar Ti3C2 Nanosheets: An Electroactive Interface for Noninvasive Diagnosis of Oral Carcinoma via Salivary TNF-α Sensing DOI

Sunil Vasu,

Damini Verma,

Omal Surya Souraph S

et al.

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

In the fast-paced quest for early cancer detection, noninvasive screening techniques have emerged as game-changers, offering simple and accessible avenues precession diagnostics. line with this, our study highlights potential of silver nanoparticle-decorated titanium carbide MXene nanosheets (Ti3C2_AgNPs) an electroactive interface diagnosis oral carcinoma based on prevalence salivary biomarker, tumor necrosis factor-α (TNF-α). An in situ reduction was utilized to synthesize Ti3C2_AgNPs nanohybrid, wherein Ti3C2 acts reducing agent, resulting nanohybrid subjected various characterization examine optical, structural, morphological attributes. The results revealed that spherical AgNPs formed surface by virtue low-valent Ti species present Ti3C2, which facilitated AgNO3 AgNPs. Furthermore, electrochemical nanohybrid-modified screen-printed electrode (Ti3C2_AgNPs/SPE) indicated enhanced heterogeneous electron transfer kinetics. With these encouraging results, employed immobilization matrix TNF-α antibodies applied sensing. Analytical studies fabricated immunosensor, conducted differential pulse voltammetry (DPV), exhibited a broader linear range (1 180 pg mL–1), low limit detection (0.97 high sensitivity (1.214 μA mL pg–1 cm–2) specificity, even artificial saliva, indicating its reliability diagnosis. Therefore, Ti3C2_AgNP seems promising candidate effective sensing could also be explored other biomarkers.

Language: Английский

Citations

2
Perylene Diimide Based Fluorescent Sensors for Aqueous Detection of Perfluorooctane Sulfonate (PFOS) DOI
Rana Dalapati, Saravanakumar Manickam, Jiangfan Shi

et al.

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1341, P. 343670 - 343670

Published: Jan. 15, 2025

Language: Английский

Citations

1
2D MXene nanosheets latest advances in electrochemical applications including energy storage and supercapacitors DOI

Farnaz Solaimany,

Ali Dashan,

Houra Pezeshk‐Fallah

et al.

Journal of Energy Storage, Journal Year: 2025, Volume and Issue: 111, P. 115341 - 115341

Published: Jan. 24, 2025

Language: Английский

Citations

1
Electrochemical Sensing of Perfluorooctanoic Acid via a Rationally Designed Fluorine-Functionalized Cu-MOF and In-Depth Analysis of Sensing Mechanism DOI
Xuan Zheng,

Cun Li,

Nairong Yang

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Perfluorooctanoic acid (PFOA), a prominent member of the per- and polyfluoroalkyl substance (PFAS) family, has emerged as new perpetual pollutant posing significant environmental health risks, necessitating developing highly selective materials for its sensitive detection in water. In this work, we developed an electroactive fluorine-functionalized Cu-MOF (F-Cu-NH2BDC) through postmodification copper-2-amino-terephthalic (Cu-NH2BDC) MOF with 2,3,5,6-tetrafluoroterephthalaldehyde (TFTA). Experimental computational results suggested that F-F interactions between decorated tetrafluorobenzaldehyde groups PFOA, well among PFOA molecules themselves, would induce self-aggregation on surfaces or pores F-Cu-NH2BDC. This specific aggregation inhibited contact electron transfer F-Cu-NH2BDC electrolyte, resulting decrease inherent electrochemical Cu2+/Cu+ redox signal from Based this, F-Cu-NH2BDC-based label- probe-free sensor was exploited excellent linear range 5 pM to 500 μM extremely low limit 3.54 pM, surpassing most currently reported nonelectrochemical PFAS sensors. also exhibited good stability, reproducibility, anti-interference performance, enabling accurate measurement concentrations actual commercial drinking These findings shed light design sensors utilizing interaction working mechanism.

Language: Английский

Citations

1
Electrochemical Detection of Per- and Polyfluoroalkyl Substances: A Review DOI

Aashutosh Dube,

Shweta J. Malode, Hanan Akhdar

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114653 - 114653

Published: March 1, 2025

Language: Английский

Citations

1
Rapid Single-Step Detection of Polyfluoroalkyl Substances (PFAS) Using Electropolymerized Phenoxazine Dyes DOI
Abd Ur Rehman, Daniel Andreescu, Swapnil Tiwari

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(44), P. 17506 - 17516

Published: Oct. 15, 2024

Per- and polyfluoroalkyl substances (PFAS) are highly stable ubiquitous contaminants that have been recently added to the list of regulated chemicals. While methods for PFAS detection exist, analysis is difficult, involving a tedious protocol expensive instrumentation. Here, we demonstrate first implementation phenoxazine dye as sensing probe facilitates rapid inexpensive representative PFAS, e.g., perfluorooctanesulfonic acid (PFOS) perfluorooctanoic (PFOA), at sensitivity levels covering established Environmental Protection Agency (EPA) limits. The method comprises an electrode modified with redox film Meldola blue (MB) in its electropolymerized form (

Language: Английский

Citations

4
Dual-mode electrochemical and SERS detection of PFAS using functional porous substrate DOI Creative Commons

Karolina Kukrálová,

Elena Miliutina, Olga Guselnikova

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 364, P. 143149 - 143149

Published: Aug. 24, 2024

Human activity is the cause of continuous and gradual grooving environmental contaminants, where some released toxic dangerous compounds cannot be degraded under natural conditions, resulting in a serious safety issue. Among them are widely occurring water-soluble perfluoroalkyl polyfluoroalkyl substances (PFAS), sometimes called "forever chemicals" because impossibility their degradation. Hence, reliable, expressive, simple method should developed to monitor eliminate risks associated with these compounds. In this study, we propose simple, express, portable detection for fluoro-alkyl (PFOA GenX) using mutually complementary methods: electrochemical impedance spectroscopy (EIS) surface-enhanced Raman (SERS). To implement our method, special substrates based on porous silicon top-deposited plasmon-active Au layer by subsequently grafting -C

Language: Английский

Citations

3
Advanced laser-induced graphene-based electrochemical immunosensor for the detection of C-reactive protein DOI
Sri Ramulu Torati,

Gymama Slaughter

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 161, P. 108842 - 108842

Published: Oct. 30, 2024

Language: Английский

Citations

3
Rapid and Ultrasensitive Sensor for Point-of-Use Detection of Perfluorooctanoic Acid Based on Molecular Imprinted Polymer and AC Electrothermal Effect DOI Creative Commons
Niloufar Amin, Jiangang Chen, Nhat Thien Nguyen

et al.

Micromachines, Journal Year: 2025, Volume and Issue: 16(3), P. 283 - 283

Published: Feb. 28, 2025

Perfluorooctanoic acid (PFOA) is one of the most persistent and bioaccumulative water contaminants. Sensitive, rapid, in-field analysis needed to ensure safe supplies. Here, we present a single step (one shot) rapid sensor capable measuring PFOA at sub-quadrillion (ppq) level, 4.5 × 10−4 ppq, within 10 s. This innovative employs synergistic combination molecularly imprinted polymer (MIP)-modified gold interdigitated microelectrode chip AC electrothermal effects (ACETs), which enhance detection sensitivity by facilitating accelerated movement molecules towards specific recognition sites on sensing surface. The application predetermined signal induces microfluidic enrichment results in concentration-dependent changes interfacial capacitance during binding process. enables real-time, quantification with exceptional sensitivity. We achieved linear dynamic range spanning from 0.4 40 fg/L (4 10−7–4 10−5 ppt) demonstrated good selectivity (~1:100) against other PFAS compounds, including perfluorooctanoic (PFOS), PBS buffer. sensor’s straightforward operation, cost-effectiveness, elimination need for external redox probes, compact design, functionality relatively resistant environmental matrices position it as an outstanding candidate deployment practical applications.

Language: Английский

Citations

0
Fluorescent Sodium Alginate Hydrogel–Carbon Dots Sensor for Detecting Perfluorooctanoic Acid in Potable Water DOI
Somayeh Mohammadi, Christian Sandoval‐Pauker,

Zayra N. Dorado

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 3, 2025

Per- and polyfluoroalkyl substances (PFASs), especially perfluorooctanoic acid (PFOA), are emerging environmental health concerns due to their persistence, resistance degradation, bioaccumulation. In this study, we developed a sensitive selective detection platform based on sodium alginate (SA) hydrogel modified with nitrogen fluorinated carbon dots (N,F-CDs) enhance the of PFOA in natural engineered water systems. The SA hydrogel-N,F-CD composite exhibited strong fluorescence at 480 nm after optimization, achieving limit as low 0.001 ppt. sensor was characterized by using Scanning Electron Microscopy (SEM), Fourier-Transform Infrared Spectroscopy (FT-IR), Powder X-ray Diffraction (PXRD), Photoelectron (XPS), zeta potential spectroscopy, revealing its structural integrity, functional groups, surface charge hydrogel-N,F-CDs network. Sensitivity assessments demonstrated linear response concentrations ranging from 1 66 ppq. Selectivity tests confirmed sensor's ability distinguish other perfluorinated compounds, minimal interference substances. practical applicability validated spiked recovery experiments tap samples various locations, rates between 94% 106.6%. This offers reliable, efficient, highly for PFAS, demonstrating real-world PFAS-monitoring applications.

Language: Английский

Citations

0