ACS ES&T Water,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 26, 2024
Conventional
detection
technologies
for
environmental
contaminants
have
primarily
focused
on
providing
accurate
qualitative
and
quantitative
evaluations
single
pollutant
types,
leading
to
increased
costs
an
inability
satisfy
the
growing
demand
detecting
a
broader
spectrum
of
pollutants.
Here,
we
introduced
novel
analytical
method
simultaneously
measure
concentration
levels
diverse
pollutants,
characterized
by
their
distinct
properties,
across
complex
biological
samples.
Per-
polyfluoroalkyl
substances
(PFAS)
antibiotics
were
used
as
case
study
due
frequency
in
environment
known
impacts
Our
harnesses
salting-out
effect
sodium
chloride
proteins
within
muscle
tissues
178
marine
species,
which
significantly
reduces
addition
extraneous
substances,
mitigates
matrix
interference,
avoids
reliance
solid-phase
extraction
or
dispersive
agents.
The
provides
simultaneous
pretreatment
several
compounds,
with
limits
from
0.002
0.41
ng/g
dry
weight,
are
substantially
lower
than
conventional
methods.
Overall,
this
streamlines
efficiency,
decreases
costs,
lessens
effects,
sets
solid
groundwork
future
applications
concurrent
environmentally
pertinent
pollutants
varied
characteristics.
ACS Applied Bio Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 9, 2025
In
the
fast-paced
quest
for
early
cancer
detection,
noninvasive
screening
techniques
have
emerged
as
game-changers,
offering
simple
and
accessible
avenues
precession
diagnostics.
line
with
this,
our
study
highlights
potential
of
silver
nanoparticle-decorated
titanium
carbide
MXene
nanosheets
(Ti3C2_AgNPs)
an
electroactive
interface
diagnosis
oral
carcinoma
based
on
prevalence
salivary
biomarker,
tumor
necrosis
factor-α
(TNF-α).
An
in
situ
reduction
was
utilized
to
synthesize
Ti3C2_AgNPs
nanohybrid,
wherein
Ti3C2
acts
reducing
agent,
resulting
nanohybrid
subjected
various
characterization
examine
optical,
structural,
morphological
attributes.
The
results
revealed
that
spherical
AgNPs
formed
surface
by
virtue
low-valent
Ti
species
present
Ti3C2,
which
facilitated
AgNO3
AgNPs.
Furthermore,
electrochemical
nanohybrid-modified
screen-printed
electrode
(Ti3C2_AgNPs/SPE)
indicated
enhanced
heterogeneous
electron
transfer
kinetics.
With
these
encouraging
results,
employed
immobilization
matrix
TNF-α
antibodies
applied
sensing.
Analytical
studies
fabricated
immunosensor,
conducted
differential
pulse
voltammetry
(DPV),
exhibited
a
broader
linear
range
(1
180
pg
mL–1),
low
limit
detection
(0.97
high
sensitivity
(1.214
μA
mL
pg–1
cm–2)
specificity,
even
artificial
saliva,
indicating
its
reliability
diagnosis.
Therefore,
Ti3C2_AgNP
seems
promising
candidate
effective
sensing
could
also
be
explored
other
biomarkers.
Analytical Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 10, 2025
Perfluorooctanoic
acid
(PFOA),
a
prominent
member
of
the
per-
and
polyfluoroalkyl
substance
(PFAS)
family,
has
emerged
as
new
perpetual
pollutant
posing
significant
environmental
health
risks,
necessitating
developing
highly
selective
materials
for
its
sensitive
detection
in
water.
In
this
work,
we
developed
an
electroactive
fluorine-functionalized
Cu-MOF
(F-Cu-NH2BDC)
through
postmodification
copper-2-amino-terephthalic
(Cu-NH2BDC)
MOF
with
2,3,5,6-tetrafluoroterephthalaldehyde
(TFTA).
Experimental
computational
results
suggested
that
F-F
interactions
between
decorated
tetrafluorobenzaldehyde
groups
PFOA,
well
among
PFOA
molecules
themselves,
would
induce
self-aggregation
on
surfaces
or
pores
F-Cu-NH2BDC.
This
specific
aggregation
inhibited
contact
electron
transfer
F-Cu-NH2BDC
electrolyte,
resulting
decrease
inherent
electrochemical
Cu2+/Cu+
redox
signal
from
Based
this,
F-Cu-NH2BDC-based
label-
probe-free
sensor
was
exploited
excellent
linear
range
5
pM
to
500
μM
extremely
low
limit
3.54
pM,
surpassing
most
currently
reported
nonelectrochemical
PFAS
sensors.
also
exhibited
good
stability,
reproducibility,
anti-interference
performance,
enabling
accurate
measurement
concentrations
actual
commercial
drinking
These
findings
shed
light
design
sensors
utilizing
interaction
working
mechanism.
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(44), P. 17506 - 17516
Published: Oct. 15, 2024
Per-
and
polyfluoroalkyl
substances
(PFAS)
are
highly
stable
ubiquitous
contaminants
that
have
been
recently
added
to
the
list
of
regulated
chemicals.
While
methods
for
PFAS
detection
exist,
analysis
is
difficult,
involving
a
tedious
protocol
expensive
instrumentation.
Here,
we
demonstrate
first
implementation
phenoxazine
dye
as
sensing
probe
facilitates
rapid
inexpensive
representative
PFAS,
e.g.,
perfluorooctanesulfonic
acid
(PFOS)
perfluorooctanoic
(PFOA),
at
sensitivity
levels
covering
established
Environmental
Protection
Agency
(EPA)
limits.
The
method
comprises
an
electrode
modified
with
redox
film
Meldola
blue
(MB)
in
its
electropolymerized
form
(
Chemosphere,
Journal Year:
2024,
Volume and Issue:
364, P. 143149 - 143149
Published: Aug. 24, 2024
Human
activity
is
the
cause
of
continuous
and
gradual
grooving
environmental
contaminants,
where
some
released
toxic
dangerous
compounds
cannot
be
degraded
under
natural
conditions,
resulting
in
a
serious
safety
issue.
Among
them
are
widely
occurring
water-soluble
perfluoroalkyl
polyfluoroalkyl
substances
(PFAS),
sometimes
called
"forever
chemicals"
because
impossibility
their
degradation.
Hence,
reliable,
expressive,
simple
method
should
developed
to
monitor
eliminate
risks
associated
with
these
compounds.
In
this
study,
we
propose
simple,
express,
portable
detection
for
fluoro-alkyl
(PFOA
GenX)
using
mutually
complementary
methods:
electrochemical
impedance
spectroscopy
(EIS)
surface-enhanced
Raman
(SERS).
To
implement
our
method,
special
substrates
based
on
porous
silicon
top-deposited
plasmon-active
Au
layer
by
subsequently
grafting
-C
Micromachines,
Journal Year:
2025,
Volume and Issue:
16(3), P. 283 - 283
Published: Feb. 28, 2025
Perfluorooctanoic
acid
(PFOA)
is
one
of
the
most
persistent
and
bioaccumulative
water
contaminants.
Sensitive,
rapid,
in-field
analysis
needed
to
ensure
safe
supplies.
Here,
we
present
a
single
step
(one
shot)
rapid
sensor
capable
measuring
PFOA
at
sub-quadrillion
(ppq)
level,
4.5
×
10−4
ppq,
within
10
s.
This
innovative
employs
synergistic
combination
molecularly
imprinted
polymer
(MIP)-modified
gold
interdigitated
microelectrode
chip
AC
electrothermal
effects
(ACETs),
which
enhance
detection
sensitivity
by
facilitating
accelerated
movement
molecules
towards
specific
recognition
sites
on
sensing
surface.
The
application
predetermined
signal
induces
microfluidic
enrichment
results
in
concentration-dependent
changes
interfacial
capacitance
during
binding
process.
enables
real-time,
quantification
with
exceptional
sensitivity.
We
achieved
linear
dynamic
range
spanning
from
0.4
40
fg/L
(4
10−7–4
10−5
ppt)
demonstrated
good
selectivity
(~1:100)
against
other
PFAS
compounds,
including
perfluorooctanoic
(PFOS),
PBS
buffer.
sensor’s
straightforward
operation,
cost-effectiveness,
elimination
need
for
external
redox
probes,
compact
design,
functionality
relatively
resistant
environmental
matrices
position
it
as
an
outstanding
candidate
deployment
practical
applications.
Analytical Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 3, 2025
Per-
and
polyfluoroalkyl
substances
(PFASs),
especially
perfluorooctanoic
acid
(PFOA),
are
emerging
environmental
health
concerns
due
to
their
persistence,
resistance
degradation,
bioaccumulation.
In
this
study,
we
developed
a
sensitive
selective
detection
platform
based
on
sodium
alginate
(SA)
hydrogel
modified
with
nitrogen
fluorinated
carbon
dots
(N,F-CDs)
enhance
the
of
PFOA
in
natural
engineered
water
systems.
The
SA
hydrogel-N,F-CD
composite
exhibited
strong
fluorescence
at
480
nm
after
optimization,
achieving
limit
as
low
0.001
ppt.
sensor
was
characterized
by
using
Scanning
Electron
Microscopy
(SEM),
Fourier-Transform
Infrared
Spectroscopy
(FT-IR),
Powder
X-ray
Diffraction
(PXRD),
Photoelectron
(XPS),
zeta
potential
spectroscopy,
revealing
its
structural
integrity,
functional
groups,
surface
charge
hydrogel-N,F-CDs
network.
Sensitivity
assessments
demonstrated
linear
response
concentrations
ranging
from
1
66
ppq.
Selectivity
tests
confirmed
sensor's
ability
distinguish
other
perfluorinated
compounds,
minimal
interference
substances.
practical
applicability
validated
spiked
recovery
experiments
tap
samples
various
locations,
rates
between
94%
106.6%.
This
offers
reliable,
efficient,
highly
for
PFAS,
demonstrating
real-world
PFAS-monitoring
applications.