RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(32), P. 23147 - 23151
Published: Jan. 1, 2024
Zn(OTf)2-catalyzed
intra-
and
intermolecular
selenofunctionalization
of
alkenes
was
achieved
with
electrophilic
N-phenylselenophthalimide.
This
method
provides
straightforward
efficient
access
to
various
seleno-substituted
heterocycles
vicinal
Se
heteroatom-disubstituted
molecules
under
mild
conditions.
reaction
is
compatible
substrates/functional
groups,
preliminary
studies
on
the
mechanistic
were
also
conducted.
Organic Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
10(19), P. 4972 - 5027
Published: Jan. 1, 2023
This
review
comprehensively
summarizes
the
dichalcogenative
functionalization
of
unsaturated
compounds
over
past
decade.
The
scopes,
limitations
and
detailed
reaction
mechanisms
are
also
discussed.
The Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
88(11), P. 7431 - 7447
Published: May 23, 2023
Three-component
selenofunctionalization
processes
of
olefins,
diselenides
and
sulfonamides,
water,
alcohols,
or
acids
utilizing
1-fluoropyridinium
triflate
(FP-OTf)
as
a
reaction
promoter
are
reported.
Under
the
optimal
conditions,
broad
range
vicinally
functionalized
selenide
derivatives
was
accessible
with
high
yields
excellent
functional
group
compatibilities.
Mechanistic
studies
revealed
that
FP-OTf
played
key
role
in
this
process.
SynOpen,
Journal Year:
2023,
Volume and Issue:
07(04), P. 511 - 520
Published: Oct. 1, 2023
Abstract
Electrochemical
synthesis,
due
to
its
environmentally
benign,
sustainable,
and
practical
nature,
has
become
an
appealing
powerful
substitute
for
traditional
methods
oxidizing
reducing
organic
compounds.
Thus,
numerous
valuable
changes
have
been
established
in
the
field
of
synthesis
through
utilization
electrochemistry.
Among
these
electrochemical
transformations,
formation
C–Se
bonds
stands
out
as
exceptionally
noteworthy
reaction
type.
In
this
graphical
review,
we
present
a
succinct
summary
progress
utilizing
strategies
synthesizing
organoselenium
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(21), P. 3916 - 3921
Published: May 22, 2023
We
report
a
copper
metallaphotocatalytic
1,2-difunctionalization
of
terminal
alkynes
with
N-hydroxyphthalimide
(NHP)
esters
and
readily
available
silyl
reagents
(TMSCN
TMSNCS)
to
access
stereodefined
trisubstituted
alkenes,
including
(E)-alkenyl
nitriles
thiocyanates.
The
reaction
proceeds
excellent
anti-stereoselectivity
demonstrates
broad
compatibility
wide
range
NHP
as
alkyl
radical
precursors.
Experimental
computational
studies
have
been
performed
gain
insight
into
the
mechanism.
The Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
88(23), P. 16122 - 16131
Published: Nov. 14, 2023
We
have
developed
the
synthesis
of
α-substituted
ketone
compounds
with
enol
acetates
in
an
electrochemical
way.
By
using
cheap
NH4SCN
and
MeOH
as
radical
sources,
a
series
valuable
α-thiocyanates/methoxy
ketones
were
synthesized
under
mild
electrolysis
conditions
acceptable
yields
diverse
functional
group
compatibility.
Additionally,
scale-up
experiment
synthetic
transformations
reveal
potential
applications
organic
synthesis.
Chinese Journal of Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 17, 2025
Comprehensive
Summary
A
practical
photocatalytic
annulation‐biselenylation
strategy
has
been
developed
for
the
efficient
synthesis
of
biselenium‐substituted
1‐indanones
(38
examples
in
total)
with
generally
good
yields
(up
to
95%)
and
excellent
stereoselectivity
(>19
:
1
Z
/
E
ratio)
by
employing
enynones
diaryl
selenides
as
starting
materials
under
photosensitizer‐free
conditions.
The
reaction
mechanism
involves
a
cascade
process
comprising
homolytic
cleavage,
radical
addition,
5‐
exo
‐
dig
cyclization,
capture,
enabling
sequential
formation
multiple
bonds,
such
C(sp
3
)‐Se,
)‐C(sp
2
),
)‐Se
rapidly
construct
molecular
complexity.
Notably,
this
approach
demonstrates
wide
substrate
compatibility
tolerability
towards
various
functional
groups.
It
is
further
characterized
its
remarkable
efficiency
creating
chemical
bonds
achieving
high
atomic
utilization
100%.
